Protecting the fetus against HIV infection: a systematic review of placental transfer of antiretrovirals (Q34429204)

2 August 2017

1 reference

title

Protecting the fetus against HIV infection: a systematic review of placental transfer of antiretrovirals (English)

1 reference

2 August 2017

anti-retroviral agent

0 references

1 reference

Shelley A McCormack

1

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PubMed ID

25223699

2 August 2017

Brookie M Best

series ordinal

2

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2 August 2017

1 November 2014

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Clinical Pharmacokinetics

2 August 2017

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2 August 2017

53

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2 August 2017

11

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2 August 2017

989-1004

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https://scigraph.springernature.com/pub.10.1007/s40262-014-0185-7

2 August 2017

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cites work

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Hair and plasma data show that lopinavir, ritonavir, and efavirenz all transfer from mother to infant in utero, but only efavirenz transfers via breastfeeding

6 July 2018

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6 July 2018

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6 July 2018

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Genotoxic signature in cord blood cells of newborns exposed in utero to a Zidovudine-based antiretroviral combination

6 July 2018

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Population pharmacokinetic analysis of a nevirapine-based HIV-1 prevention of mother-to-child transmission program in Uganda to assess the impact of different dosing regimens for newborns

6 July 2018

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Pharmacokinetics of an increased atazanavir dose with and without tenofovir during the third trimester of pregnancy

6 July 2018

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Steady-state pharmacokinetics, cord blood concentrations, and safety of ritonavir-boosted fosamprenavir in pregnancy

6 July 2018

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Reduced indinavir exposure during pregnancy

6 July 2018

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Placental transfer of maraviroc in an ex vivo human cotyledon perfusion model and influence of ABC transporter expression.

6 July 2018

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The pharmacokinetics, safety and efficacy of tenofovir and emtricitabine in HIV-1-infected pregnant women

6 July 2018

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Novel method to assess antiretroviral target trough concentrations using in vitro susceptibility data

6 July 2018

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Effect of pregnancy on emtricitabine pharmacokinetics

6 July 2018

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6 July 2018

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Improved oral bioavailability of lopinavir in melt-extruded tablet formulation reduces impact of third trimester on lopinavir plasma concentrations

6 July 2018

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Efavirenz pharmacokinetics during the third trimester of pregnancy and postpartum

6 July 2018

1 reference

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Pharmacokinetics and placental transfer of single-dose tenofovir 1% vaginal gel in term pregnancy.

6 July 2018

1 reference

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Safety and exposure of once-daily ritonavir-boosted atazanavir in HIV-infected pregnant women

6 July 2018

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Plasma and intracellular tenofovir pharmacokinetics in the neonate (ANRS 12109 trial, step 2)

6 July 2018

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Very high concentrations of active intracellular phosphorylated emtricitabine in neonates (ANRS 12109 trial, step 2).

6 July 2018

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Atazanavir pharmacokinetics with and without tenofovir during pregnancy

6 July 2018

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Population pharmacokinetics of nevirapine in HIV-1-infected pregnant women and their neonates

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214885

Lopinavir tablet pharmacokinetics with an increased dose during pregnancy

6 July 2018

1 reference

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The effect of probenecid and MK-571 on the feto-maternal transfer of saquinavir in dually perfused human term placenta

6 July 2018

1 reference

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Binding of lopinavir to human alpha1-acid glycoprotein and serum albumin

6 July 2018

1 reference

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Genital tract, cord blood, and amniotic fluid exposures of seven antiretroviral drugs during and after pregnancy in human immunodeficiency virus type 1-infected women

6 July 2018

1 reference

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Population pharmacokinetics of emtricitabine in human immunodeficiency virus type 1-infected pregnant women and their neonates

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214885

Lopinavir exposure with an increased dose during pregnancy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214885

Pharmacokinetics of new 625 mg nelfinavir formulation during pregnancy and postpartum.

6 July 2018

1 reference

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Enhancement of zidovudine uptake by dehydroepiandrosterone sulfate in rat syncytiotrophoblast cell line TR-TBT 18d-1.

6 July 2018

1 reference

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Pharmacokinetics and safety of nelfinavir when used in combination with zidovudine and lamivudine in HIV-infected pregnant women: Pediatric AIDS Clinical Trials Group (PACTG) Protocol 353.

6 July 2018

1 reference

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Chronic administration of nevirapine during pregnancy: impact of pregnancy on pharmacokinetics

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214885

Inhibition of placental P-glycoprotein: impact on indinavir transfer to the foetus.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214885

Pharmacokinetic modelling of the placental transfer of nelfinavir and its M8 metabolite: a population study using 75 maternal-cord plasma samples

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214885

Animal models of human placentation--a review

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214885

Differential protein binding of indinavir and saquinavir in matched maternal and umbilical cord plasma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214885

Pharmacokinetics of nelfinavir in HIV-1-infected pregnant and nonpregnant women

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214885

Differential bidirectional transfer of indinavir in the isolated perfused human placenta

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214885

Mother-to-child transmission of HIV infection in the era of highly active antiretroviral therapy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214885

Maternal-fetal transfer and amniotic fluid accumulation of nucleoside analogue reverse transcriptase inhibitors in human immunodeficiency virus-infected pregnant women

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214885

Natural variation of drug susceptibility in wild-type human immunodeficiency virus type 1

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214885

Pharmacokinetics of saquinavir plus low-dose ritonavir in human immunodeficiency virus-infected pregnant women

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214885

Predose infant nevirapine concentration with the two-dose intrapartum neonatal nevirapine regimen: association with timing of maternal intrapartum nevirapine dose

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214885

Safety and efficacy of saquinavir soft-gelatin capsules + zidovudine + optional lamivudine in pregnancy and prevention of vertical HIV transmission

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214885

Hollow-fiber unit evaluation of a new human immunodeficiency virus type 1 protease inhibitor, BMS-232632, for determination of the linked pharmacodynamic variable

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214885

Maternal-fetal transfer and amniotic fluid accumulation of lamivudine in human immunodeficiency virus-infected pregnant women

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214885

A phase I/II study of the safety and pharmacokinetics of nevirapine in HIV-1-infected pregnant Ugandan women and their neonates (HIVNET 006).

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214885

The ex vivo human placental transfer of the anti-HIV nucleoside inhibitor abacavir and the protease inhibitor amprenavir

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214885

Pharmacokinetics of nevirapine in human immunodeficiency virus type 1-infected pregnant women and their neonates. Pediatric AIDS Clinical Trials Group Protocol 250 Team

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214885

Transfer of dideoxyinosine across the human isolated placenta

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214885

The transfer of anti-human immunodeficiency virus nucleoside compounds by the term human placenta

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214885

Factors associated with mother-to-child transmission of HIV-1 despite a maternal viral load <500 copies/ml at delivery: a case-control study nested in the French perinatal cohort (EPF-ANRS CO1).

6 July 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-014-0185-7

Residual HIV-1 RNA and HIV-1 DNA production in the genital tract reservoir of women treated with HAART: the prospective ANRS EP24 GYNODYN study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-014-0185-7

Impact of pregnancy on abacavir pharmacokinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-014-0185-7

Pharmacokinetics of zidovudine and lamivudine in neonates following coadministration of oral doses every 12 hours

21 January 2018

1 reference

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Pharmacokinetics and safety of stavudine in HIV-infected pregnant women and their infants: Pediatric AIDS Clinical Trials Group protocol 332.

21 January 2018

1 reference

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The pharmacokinetics and safety of zidovudine in the third trimester of pregnancy for women infected with human immunodeficiency virus and their infants: phase I acquired immunodeficiency syndrome clinical trials group study (protocol 082). Zidovudi

21 January 2018

1 reference

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Pharmacokinetics and antiretroviral activity of lamivudine alone or when coadministered with zidovudine in human immunodeficiency virus type 1-infected pregnant women and their offspring

21 January 2018

1 reference

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Systemic pharmacokinetics and cellular pharmacology of zidovudine in human immunodeficiency virus type 1-infected women and newborn infants

21 January 2018

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Successful use of darunavir, etravirine, enfuvirtide and tenofovir/emtricitabine in pregnant woman with multiclass HIV resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-014-0185-7

Transplacental passage of protease inhibitors at delivery

21 January 2018

1 reference

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Transplacental transfer of antiretroviral drugs and newborn birth weight in HIV-infected pregnant women

21 January 2018

1 reference

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Pharmacokinetics, safety and transplacental passage of rilpivirine in pregnancy: two cases.

21 January 2018

1 reference

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Atazanavir plus low-dose ritonavir in pregnancy: pharmacokinetics and placental transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-014-0185-7

Human placental transfer of atazanavir: a case report.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-014-0185-7

Reduced lopinavir exposure during pregnancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-014-0185-7

Free and total plasma levels of lopinavir during pregnancy, at delivery and postpartum: implications for dosage adjustments in pregnant women

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-014-0185-7

Concentrations of protease inhibitors in cord blood after in utero exposure

21 January 2018

1 reference

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Maternal-fetal transfer and amniotic fluid accumulation of protease inhibitors in pregnant women who are infected with human immunodeficiency virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-014-0185-7

The pharmacokinetics of nelfinavir and M8 during pregnancy and post partum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-014-0185-7

Pharmacokinetics of saquinavir-SGC in HIV-infected pregnant women

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-014-0185-7

Transplacental passage of ritonavir-boosted darunavir in two pregnant women

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-014-0185-7

Use of darunavir/ritonavir once daily in treatment-naive pregnant woman: pharmacokinetics, compartmental exposure, efficacy and safety

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-014-0185-7

Decreased plasma levels of darunavir/ritonavir in a vertically infected pregnant woman carrying multiclass-resistant HIV type-1.

21 January 2018

1 reference

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Pharmacokinetic profile in late pregnancy and cord blood concentration of tipranavir and enfuvirtide

21 January 2018

1 reference

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Enfurvitide prevents vertical transmission of multidrug-resistant HIV-1 in pregnancy but does not cross the placenta.

21 January 2018

1 reference

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[Use of enfurvitide in pregnancy in HIV positive women in seven cases].

21 January 2018

1 reference

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High neonatal concentrations of raltegravir following transplacental transfer in HIV-1 positive pregnant women

21 January 2018

1 reference

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Population pharmacokinetics of tenofovir in HIV-1-infected pregnant women and their neonates (ANRS 12109).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-014-0185-7

Maternal-fetal transfer of saquinavir studied in the ex vivo placental perfusion model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-014-0185-7

Influence of adenosine triphosphate and ABCB1 (MDR1) genotype on the P-glycoprotein-dependent transfer of saquinavir in the dually perfused human placenta

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-014-0185-7

Functional role of P-glycoprotein in the human blood-placental barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-014-0185-7

Contribution and limit of the model of perfused cotyledon to the study of placental transfer of drugs. Example of a protease inhibitor of HIV: nelfinavir

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-014-0185-7

Placental transfer of enfuvirtide in the ex vivo human placenta perfusion model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-014-0185-7

Increased expression of MDR1 mRNAs and P-glycoprotein in placentas from HIV-1 infected women.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-014-0185-7

Pharmacokinetics of oral zidovudine administered during labour: a preliminary study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-014-0185-7

Placental transfer of Zidovudine in first trimester of pregnancy

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214885

Transplacental passage of etravirine and maraviroc in a multidrug-experienced HIV-infected woman failing on darunavir-based HAART in late pregnancy

27 October 2018

1 reference

12 December 2020

Placental transfer of lopinavir/ritonavir in the ex vivo human cotyledon perfusion model

1 reference

12 December 2020

Placental transfer and pharmacokinetics of lopinavir and other protease inhibitors in combination with nevirapine at delivery

1 reference

12 December 2020

Raltegravir in the prevention of mother-to-child transmission of HIV-1: effective transplacental transfer and delayed plasma clearance observed in preterm neonates

1 reference

12 December 2020

Transfer and metabolism of dideoxyinosine by the perfused human placenta

1 reference

12 December 2020

The ex vivo transfer of the anti-HIV nucleoside compound d4T in the human placenta

1 reference

12 December 2020

The maternal-fetal transfer of lamivudine in the ex vivo human placenta

1 reference

12 December 2020

Pharmacokinetic and toxicity studies of AZT (zidovudine) following perfusion of human term placenta for 14 hours

1 reference

12 December 2020

Human placenta does not Reduce AZT (zidovudine) to 3'-amino-3'-deoxythymidine

1 reference

12 December 2020

Safety and pharmacokinetics of etravirine in pregnant HIV-1-infected women

1 reference

12 December 2020

Atazanavir in pregnancy: impact on neonatal hyperbilirubinemia

1 reference

12 December 2020

Transplacental passage of nevirapine, nelfinavir and lopinavir

1 reference

12 December 2020

Pharmacokinetic and safety of raltegravir in pregnancy

1 reference

12 December 2020

Oral zidovudine during labor to prevent perinatal HIV transmission, Bangkok: tolerance and zidovudine concentration in cord blood. Bangkok Collaborative Perinatal HIV Transmission Study Group

1 reference

12 December 2020

Pharmacological implications of lengthened in-utero exposure to nevirapine

1 reference

12 December 2020

Incorporation of zidovudine into cord blood DNA of infants and peripheral blood DNA of their HIV-1-positive mothers

1 reference

12 December 2020

[Preliminary study on the transport of AZT (Retrovir-zidovudine) through the placenta]

1 reference

12 December 2020

Pharmacokinetic disposition of zidovudine during pregnancy

1 reference

12 December 2020

Placental passage of azathiothymidine (AZT) during the second trimester of pregnancy: study by direct fetal blood sampling under ultrasound

1 reference

12 December 2020

Zidovudine Pharmacokinetics During Pregnancy

1 reference

12 December 2020

Placental transfer of ritonavir with zidovudine in the ex vivo placental perfusion model

1 reference

12 December 2020

3'-azido-3'-deoxythymidine (AZT) transplacental perfusion kinetics and DNA incorporation in normal human placentas perfused with AZT

1 reference

12 December 2020

10.1007/S40262-014-0185-7

Identifiers

DOI

1 reference

PubMed ID

25223699

Dimensions Publication ID

2 August 2017

0 references

1 reference

2 August 2017

1 reference

PubMed ID

25223699