Epithelial interleukin-25 is a key mediator in Th2-high, corticosteroid-responsive asthma (Q34425901)

2 August 2017

Epithelial interleukin-25 is a key mediator in Th2-high, corticosteroid-responsive asthma (English)

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2 August 2017

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Guohua Zhen

11

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David J Erle

object named as

David J Erle

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author name string

Dan Cheng

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2 August 2017

Zheng Xue

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2 August 2017

Lingling Yi

3

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2 August 2017

Huimin Shi

4

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2 August 2017

Kan Zhang

5

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2 August 2017

Xiaorong Huo

6

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2 August 2017

Luke R Bonser

7

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2 August 2017

Jianping Zhao

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2 August 2017

Yongjian Xu

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2 August 2017

language of work or name

English

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publication date

1 September 2014

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American Journal of Respiratory and Critical Care Medicine

2 August 2017

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2 August 2017

190

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2 August 2017

639-648

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2 August 2017

6

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Muc5b is required for airway defence

2 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214109

Innate lymphoid cells in asthma: when innate immunity comes in a Th2 flavor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214109

Increased density of intraepithelial mast cells in patients with exercise-induced bronchoconstriction regulated through epithelially derived thymic stromal lymphopoietin and IL-33.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214109

Asthma: the importance of dysregulated barrier immunity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214109

Measures of gene expression in sputum cells can identify TH2-high and TH2-low subtypes of asthma.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214109

A qPCR-based metric of Th2 airway inflammation in asthma.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214109

TH2, allergy and group 2 innate lymphoid cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214109

IL-25 drives remodelling in allergic airways disease induced by house dust mite

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214109

Epithelial cell-derived IL-25, but not Th17 cell-derived IL-17 or IL-17F, is crucial for murine asthma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214109

Periostin is a systemic biomarker of eosinophilic airway inflammation in asthmatic patients

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214109

Lebrikizumab treatment in adults with asthma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214109

T-helper cell type 2 (Th2) memory T cell-potentiating cytokine IL-25 has the potential to promote angiogenesis in asthma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214109

Protease allergens induce the expression of IL-25 via Erk and p38 MAPK pathway

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214109

Disease-associated functions of IL-33: the new kid in the IL-1 family

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214109

Epithelium: the interplay between innate and Th2 immunity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214109

IL-33 amplifies the polarization of alternatively activated macrophages that contribute to airway inflammation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214109

T-helper type 2-driven inflammation defines major subphenotypes of asthma.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214109

Identification of an interleukin (IL)-25-dependent cell population that provides IL-4, IL-5, and IL-13 at the onset of helminth expulsion

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214109

IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214109

A role for TSLP in the development of inflammation in an asthma model

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214109

Thymic stromal lymphopoietin expression is increased in asthmatic airways and correlates with expression of Th2-attracting chemokines and disease severity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214109

Characterization of within-subject responses to fluticasone and montelukast in childhood asthma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214109

Analysis of induced sputum in adults with asthma: identification of subgroup with isolated sputum neutrophilia and poor response to inhaled corticosteroids

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214109

New IL-17 family members promote Th1 or Th2 responses in the lung: in vivo function of the novel cytokine IL-25

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214109

Human epithelial cells trigger dendritic cell mediated allergic inflammation by producing TSLP.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214109

IL-25 induces IL-4, IL-5, and IL-13 and Th2-associated pathologies in vivo

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214109

Interleukin-13: central mediator of allergic asthma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214109

Evidence that severe asthma can be divided pathologically into two inflammatory subtypes with distinct physiologic and clinical characteristics

6 July 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201403-0505OC

Requirement for IL-13 independently of IL-4 in experimental asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201403-0505OC

Gamma-secretase-mediated proteolysis in cell-surface-receptor signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201403-0505OC

Increased IL-33 expression by epithelial cells in bronchial asthma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201403-0505OC

Distinguishing severe asthma phenotypes: role of age at onset and eosinophilic inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201403-0505OC

Exhaled nitric oxide identifies the persistent eosinophilic phenotype in severe refractory asthma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201403-0505OC

Sputum cytokine mapping reveals an 'IL-5, IL-17A, IL-25-high' pattern associated with poorly controlled asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201403-0505OC

Dose-ranging study of lebrikizumab in asthmatic patients not receiving inhaled steroids

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201403-0505OC

Inflammatory subtypes in asthma: assessment and identification using induced sputum

21 January 2018

1 reference

12 December 2020

Transcriptional phenotypes of asthma defined by gene expression profiling of induced sputum samples

1 reference

12 December 2020

Blocking IL-25 prevents airway hyperresponsiveness in allergic asthma

1 reference

12 December 2020

Allergen-induced expression of IL-25 and IL-25 receptor in atopic asthmatic airways and late-phase cutaneous responses

1 reference

12 December 2020

10.1164/RCCM.201403-0505OC

Identifiers

DOI

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2 August 2017

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2 August 2017

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