Probing the structural determinants for the function of intracellular loop 2 in structurally cognate G-protein-coupled receptors (Q34420977)

2 August 2017

Probing the structural determinants for the function of intracellular loop 2 in structurally cognate G-protein-coupled receptors (English)

1 reference

G protein-coupled receptor

2 August 2017

0 references

Harel Weinstein

2

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author name string

Jufang Shan

series ordinal

1

1 reference

PubMed ID

21062002

2 August 2017

Ernest L Mehler

series ordinal

3

1 reference

PubMed ID

21062002

2 August 2017

language of work or name

English

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publication date

24 November 2010

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2 August 2017

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2 August 2017

49

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2 August 2017

50

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2 August 2017

10691-10701

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All-atom empirical potential for molecular modeling and dynamics studies of proteins

2 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005261

Editing of serotonin 2C receptor mRNA in the prefrontal cortex characterizes high-novelty locomotor response behavioral trait.

6 July 2018

1 reference

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CHARMM: the biomolecular simulation program

6 July 2018

1 reference

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Identification of two distinct inactive conformations of the beta2-adrenergic receptor reconciles structural and biochemical observations

6 July 2018

1 reference

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The 2.6 angstrom crystal structure of a human A2A adenosine receptor bound to an antagonist

6 July 2018

1 reference

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PTPN11 analysis for the prenatal diagnosis of Noonan syndrome in fetuses with abnormal ultrasound findings

6 July 2018

1 reference

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Structure of a beta1-adrenergic G-protein-coupled receptor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005261

High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005261

Activation of G protein-coupled receptors: beyond two-state models and tertiary conformational changes.

6 July 2018

1 reference

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Conformational complexity of G-protein-coupled receptors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005261

Ab initio computational modeling of long loops in G-protein coupled receptors

6 July 2018

1 reference

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MultiSeq: unifying sequence and structure data for evolutionary analysis

6 July 2018

1 reference

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Ab initio computational modeling of loops in G-protein-coupled receptors: lessons from the crystal structure of rhodopsin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005261

Hallucinogen actions on 5-HT receptors reveal distinct mechanisms of activation and signaling by G protein-coupled receptors

6 July 2018

1 reference

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A beta-arrestin binding determinant common to the second intracellular loops of rhodopsin family G protein-coupled receptors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005261

Long dynamics simulations of proteins using atomistic force fields and a continuum representation of solvent effects: calculation of structural and dynamic properties

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005261

Essential role for the second extracellular loop in C5a receptor activation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005261

Molecular mechanisms of ligand binding, signaling, and regulation within the superfamily of G-protein-coupled receptors: molecular modeling and mutagenesis approaches to receptor structure and function

6 July 2018

1 reference

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The second extracellular loop of the dopamine D2 receptor lines the binding-site crevice

6 July 2018

1 reference

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A graph-theory algorithm for rapid protein side-chain prediction

6 July 2018

1 reference

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G protein selectivity is regulated by multiple intracellular regions of GPCRs

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005261

Molecular dynamics simulations of peptides and proteins with a continuum electrostatic model based on screened Coulomb potentials.

6 July 2018

1 reference

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NMR structure of the second intracellular loop of the alpha 2A adrenergic receptor: evidence for a novel cytoplasmic helix

6 July 2018

1 reference

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The binding site of aminergic G protein-coupled receptors: the transmembrane segments and second extracellular loop

6 July 2018

1 reference

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Mutations in PTPN11, encoding the protein tyrosine phosphatase SHP-2, cause Noonan syndrome

6 July 2018

1 reference

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RNA-editing of the 5-HT(2C) receptor alters agonist-receptor-effector coupling specificity

6 July 2018

1 reference

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Structural mimicry in G protein-coupled receptors: implications of the high-resolution structure of rhodopsin for structure-function analysis of rhodopsin-like receptors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005261

Crystal structure of rhodopsin: A G protein-coupled receptor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005261

Uncovering molecular mechanisms involved in activation of G protein-coupled receptors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005261

A self-consistent, microenvironment modulated screened coulomb potential approximation to calculate pH-dependent electrostatic effects in proteins

6 July 2018

1 reference

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Role of the second extracellular loop of human C3a receptor in agonist binding and receptor function

6 July 2018

1 reference

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The second intracellular loop of the m5 muscarinic receptor is the switch which enables G-protein coupling

6 July 2018

1 reference

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6 July 2018

1 reference

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Knowledge-based protein secondary structure assignment

6 July 2018

1 reference

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Comparative protein modelling by satisfaction of spatial restraints

6 July 2018

1 reference

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Hydrophobic amino acid in the i2 loop plays a key role in receptor-G protein coupling.

6 July 2018

1 reference

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Hypertelorism with Turner phenotype. A new syndrome with associated congenital heart disease

6 July 2018

1 reference

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Efficient Monte Carlo method for simulation of fluctuating conformations of native proteins.

6 July 2018

1 reference

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The retinal conformation and its environment in rhodopsin in light of a new 2.2 A crystal structure

6 July 2018

1 reference

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Key issues in the computational simulation of GPCR function: representation of loop domains.

27 October 2018

1 reference

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The interaction with the cytoplasmic loops of rhodopsin plays a crucial role in arrestin activation and binding.

27 October 2018

1 reference

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The role of hydrophobic microenvironments in modulating pKa shifts in proteins.

27 October 2018

1 reference

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Differences in conformational properties of the second intracellular loop (IL2) in 5HT(2C) receptors modified by RNA editing can account for G protein coupling efficiency

27 October 2018

1 reference

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Comparison of dielectric response models for simulating electrostatic effects in proteins

27 October 2018

1 reference

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Molecular basis of receptor/G-protein-coupling selectivity

27 October 2018

1 reference

12 December 2020

Comment on "a fast and simple method to calculate protonation states in proteins"

1 reference

12 December 2020

Three-dimensional representations of G protein-coupled receptor structures and mechanisms

1 reference

12 December 2020

An automated approach for clustering an ensemble of NMR-derived protein structures into conformationally related subfamilies

1 reference

12 December 2020

Identifiers

DOI

10.1021/BI100580S

1 reference

2 August 2017

1 reference

2 August 2017

1 reference

PubMed ID

21062002