Multidrug-resistant human sarcoma cells with a mutant P-glycoprotein, altered phenotype, and resistance to cyclosporins. (Q34416847)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9038218%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

title

Multidrug-resistant human sarcoma cells with a mutant P-glycoprotein, altered phenotype, and resistance to cyclosporins (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9038218%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

main subject

cell line

0 references

multiple drug resistance

1 reference

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9038218%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Charles Dumontet

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9038218%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

7

B I Sikic

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9038218%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

author name string

G E Durán

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9038218%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

K A Steger

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9038218%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

N J Lacayo

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9038218%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

J P Jaffrézou

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9038218%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

language of work or name

English

0 references

publication date

1 February 1997

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9038218%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

1 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9038218%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

volume

272

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9038218%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

issue

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9038218%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

page(s)

5974-5982

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9038218%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

1 November 2019

MES-SA/DxP5002

0 references

cites work

Charles F. Kettering Prize. P-glycoprotein and resistance to anticancer drugs

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.9.5974

Immunohistochemical detection of P-glycoprotein: prognostic correlation in soft tissue sarcoma of childhood

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.9.5974

Clinical correlates of MDR1 (P-glycoprotein) gene expression in ovarian and small-cell lung carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.9.5974

Drug-resistance in multiple myeloma and non-Hodgkin's lymphoma: detection of P-glycoprotein and potential circumvention by addition of verapamil to chemotherapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.9.5974

Reversal of drug-resistance by cyclosporin-A in a patient with acute myelocytic leukaemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.9.5974

Restoration of daunomycin retention in multidrug-resistant P388 cells by submicromolar concentrations of SDZ PSC 833, a nonimmunosuppressive cyclosporin derivative

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.9.5974

Phase I trial of etoposide with cyclosporine as a modulator of multidrug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.9.5974

DNA topoisomerase poisons as antitumor drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.9.5974

Mechanisms of multidrug resistance in human tumor cells. The roles of P-glycoprotein, DNA topoisomerase II, and other factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.9.5974

Determinants of Response to the DNA Topoisomerase II Inhibitors Doxorubicin and Etoposide in Human Lung Cancer Cell Lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.9.5974

Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.9.5974

Decreased mutation rate for cellular resistance to doxorubicin and suppression of mdr1 gene activation by the cyclosporin PSC 833.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.9.5974

Inhibition of lysosomal acid sphingomyelinase by agents which reverse multidrug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.9.5974

A single amino acid substitution strongly modulates the activity and substrate specificity of the mouse mdr1 and mdr3 drug efflux pumps

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.9.5974

Amino acid substitutions in the sixth transmembrane domain of P-glycoprotein alter multidrug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.9.5974

Molecular basis of preferential resistance to colchicine in multidrug-resistant human cells conferred by Gly-185----Val-185 substitution in P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.9.5974

Structurally distinct MDR modulators show specific patterns of reversal against P-glycoproteins bearing unique mutations at serine939/941.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.9.5974

Expression of a multidrug resistance gene in human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.9.5974

Modulation of multidrug resistance: at the threshold

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.9.5974

In vitro models of multiple drug resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.9.5974

An altered pattern of cross-resistance in multidrug-resistant human cells results from spontaneous mutations in the mdr1 (P-glycoprotein) gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.9.5974