BRCA1/2 mutations appear embryo-lethal unless rescued by low (CGG n<26) FMR1 sub-genotypes: explanation for the "BRCA paradox"? (Q34416088)

2 August 2017

title

BRCA1/2 mutations appear embryo-lethal unless rescued by low (CGG n<26) FMR1 sub-genotypes: explanation for the "BRCA paradox"? (English)

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2 August 2017

Andrea Weghofer

1

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2 August 2017

Muy-Kheng Tea

2

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2 August 2017

David H Barad

3

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2 August 2017

Ann Kim

4

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2 August 2017

Christian F Singer

5

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2 August 2017

Klaus Wagner

6

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2 August 2017

Norbert Gleicher

7

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2 August 2017

language of work or name

English

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publication date

12 September 2012

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2 August 2017

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2 August 2017

volume

7

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2 August 2017

issue

9

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2 August 2017

page(s)

e44753

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Creative Commons Attribution 4.0 International

2 August 2017

copyright license

start time

12 September 2012

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Cutting edge assessment of the impact of autoimmunity on female reproductive success

6 July 2018

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CGG repeat in the FMR1 gene: size matters

6 July 2018

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Association of FMR1 genotypes with in vitro fertilization (IVF) outcomes based on ethnicity/race

6 July 2018

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FMR1 genotype with autoimmunity-associated polycystic ovary-like phenotype and decreased pregnancy chance

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Breast cancer racial disparities: unanswered questions

6 July 2018

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Association of BRCA1 mutations with occult primary ovarian insufficiency: a possible explanation for the link between infertility and breast/ovarian cancer risks

6 July 2018

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Hereditary breast cancer: new genetic developments, new therapeutic avenues

6 July 2018

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Gender as risk factor for autoimmune diseases

6 July 2018

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The FMR1 premutation and reproduction

6 July 2018

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Mouse models of BRCA1 and BRCA2 deficiency: past lessons, current understanding and future prospects

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The (CGG)n repeat element within the 5' untranslated region of the FMR1 message provides both positive and negative cis effects on in vivo translation of a downstream reporter

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Senescence, aging, and malignant transformation mediated by p53 in mice lacking the Brca1 full-length isoform

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Cancer Incidence in BRCA1 mutation carriers

6 July 2018

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Cancer risks in BRCA2 mutation carriers

6 July 2018

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Partial rescue of Brca1 (5-6) early embryonic lethality by p53 or p21 null mutation.

6 July 2018

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Targeted mutations of breast cancer susceptibility gene homologs in mice: lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos

6 July 2018

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Common denominators of pregnancy and malignancy

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DNA sequencing with chain-terminating inhibitors

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Shorter androgen receptor CAG repeat lengths associated with cryptorchidism risk among Hispanic white boys.

6 July 2018

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Ovarian reserve determinations suggest new function of FMR1 (fragile X gene) in regulating ovarian ageing

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Effects of race/ethnicity on triple CGG counts in the FMR1 gene in infertile women and egg donors

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27 October 2018

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Genetics of type 1 diabetes in Asian and Caucasian populations

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Cancer risks in carriers of the BRCA1/2 Ashkenazi founder mutations

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Mosaicism in a fragile X male including a de novo deletion in the FMR1 gene.

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An Encore for the Repeats: New Insights into an Old Genetic Variant

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Prevalence and Predictors ofBRCA1andBRCA2Mutations in a Population-Based Study of Breast Cancer in White and Black American Women Ages 35 to 64 Years

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Denaturing high-performance liquid chromatography detects reliably BRCA1 and BRCA2 mutations

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12 December 2020

Evidence for further breast cancer susceptibility genes in addition to BRCA1 and BRCA2 in a population-based study

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Common denominators of pregnancy and malignancy

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12 December 2020

Mutations and alternative splicing of the BRCA1 gene in UK breast/ovarian cancer families

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p53 mutations in BRCA1-associated familial breast cancer

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BRCA1 and BRCA2 genetic testing in Hispanic patients: mutation prevalence and evaluation of the BRCAPRO risk assessment model

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12 December 2020

10.1371/JOURNAL.PONE.0044753

Identifiers

DOI

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2 August 2017

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2 August 2017

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