Ciliary neurotrophic factor (CNTF) for human retinal degeneration: phase I trial of CNTF delivered by encapsulated cell intraocular implants (Q34410761)

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scholarly article

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English	Ciliary neurotrophic factor (CNTF) for human retinal degeneration: phase I trial of CNTF delivered by encapsulated cell intraocular implants	scholarly article

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scholarly article

1 reference

Europe PubMed Central

2 August 2017

Ciliary neurotrophic factor (CNTF) for human retinal degeneration: phase I trial of CNTF delivered by encapsulated cell intraocular implants (English)

1 reference

Europe PubMed Central

2 August 2017

phase I clinical trial

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retinal degeneration

1 reference

based on heuristic

inferred from title

author name string

Paul A Sieving

1

1 reference

Europe PubMed Central

2 August 2017

Rafael C Caruso

2

1 reference

Europe PubMed Central

2 August 2017

Weng Tao

3

1 reference

Europe PubMed Central

2 August 2017

Hanna R Coleman

4

1 reference

Europe PubMed Central

2 August 2017

Darby J S Thompson

5

1 reference

Europe PubMed Central

2 August 2017

Keri R Fullmer

6

1 reference

Europe PubMed Central

2 August 2017

Ronald A Bush

7

1 reference

Europe PubMed Central

2 August 2017

language of work or name

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publication date

27 February 2006

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Europe PubMed Central

2 August 2017

number of pages

6

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based on heuristic

inferred from page(s)

Proceedings of the National Academy of Sciences of the United States of America

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Europe PubMed Central

2 August 2017

103

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Europe PubMed Central

2 August 2017

3896-3901

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Europe PubMed Central

2 August 2017

10

1 reference

Europe PubMed Central

2 August 2017

Sustained secretion of ciliary neurotrophic factor to the vitreous, using the encapsulated cell therapy-based NT-501 intraocular device.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383495

6 July 2018

Cloning, mapping, and retinal expression of the canine ciliary neurotrophic factor receptor alpha (CNTFRalpha).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383495

6 July 2018

Retinitis pigmentosa: genes, proteins and prospects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383495

6 July 2018

Encapsulated cell-based delivery of CNTF reduces photoreceptor degeneration in animal models of retinitis pigmentosa.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383495

6 July 2018

AAV-mediated delivery of ciliary neurotrophic factor prolongs photoreceptor survival in the rhodopsin knockout mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383495

6 July 2018

Restoration of cognitive and motor functions by ciliary neurotrophic factor in a primate model of Huntington's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383495

6 July 2018

Ciliary neurotrophic factor and stress stimuli activate the Jak-STAT pathway in retinal neurons and glia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383495

6 July 2018

Mammalian-cell-produced neurturin (NTN) is more potent than purified Escherichia coli-produced NTN.

1 reference

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6 July 2018

Repeated injections of a ciliary neurotrophic factor analogue leading to long-term photoreceptor survival in hereditary retinal degeneration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383495

6 July 2018

Submicrovolt flicker electroretinogram: cycle-by-cycle recording of multiple harmonics with statistical estimation of measurement uncertainty.

1 reference

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6 July 2018

Protective effect of encapsulated cells producing neurotrophic factor CNTF in a monkey model of Huntington's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383495

6 July 2018

Implants of encapsulated human CNTF-producing fibroblasts prevent behavioral deficits and striatal degeneration in a rodent model of Huntington's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383495

6 July 2018

A randomized trial of vitamin A and vitamin E supplementation for retinitis pigmentosa

1 reference

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6 July 2018

The tripartite CNTF receptor complex: activation and signaling involves components shared with other cytokines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383495

6 July 2018

Neurotrophic growth factors and neurodegenerative diseases: therapeutic potential of the neurotrophins and ciliary neurotrophic factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383495

6 July 2018

Treatment of amyotrophic lateral sclerosis using a gene therapy approach

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383495

6 July 2018

Polymer encapsulated cell lines genetically engineered to release ciliary neurotrophic factor can slow down progressive motor neuronopathy in the mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383495

6 July 2018

Neuropoietic cytokines in the hematopoietic fold

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383495

6 July 2018

Cholinergic neuronotrophic factors: intraocular distribution of trophic activity for ciliary neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383495

6 July 2018

Immunolocalization of ciliary neurotrophic factor receptor alpha (CNTFRalpha) in mammalian photoreceptor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383495

27 October 2018

Encapsulated cell-based intraocular delivery of ciliary neurotrophic factor in normal rabbit: dose-dependent effects on ERG and retinal histology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383495

27 October 2018

Expression of CNTF receptor-alpha in chick violet-sensitive cones with unique morphologic properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383495

27 October 2018

Location of CNTFRalpha on outer segments: evidence of the site of action of CNTF in rat retina

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383495

27 October 2018

Intraocular gene delivery of ciliary neurotrophic factor results in significant loss of retinal function in normal mice and in the Prph2Rd2/Rd2 model of retinal degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383495

27 October 2018

Dose-dependent neuroprotective effect of ciliary neurotrophic factor delivered via tetracycline-regulated lentiviral vectors in the quinolinic acid rat model of Huntington's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383495

27 October 2018

Effects of adeno-associated virus-vectored ciliary neurotrophic factor on retinal structure and function in mice with a P216L rds/peripherin mutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383495

27 October 2018

Long-term protection of retinal structure but not function using RAAV.CNTF in animal models of retinitis pigmentosa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383495

27 October 2018

Neuroprotective effect of a CNTF-expressing lentiviral vector in the quinolinic acid rat model of Huntington's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383495

27 October 2018

P23H rhodopsin transgenic rat: correlation of retinal function with histopathology.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383495

27 October 2018

Differential regulation of ciliary neurotrophic factor receptor-alpha expression in all major neuronal cell classes during development of the chick retina.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383495

27 October 2018

Protection of mouse photoreceptors by survival factors in retinal degenerations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383495

27 October 2018

The frequency of posterior subcapsular cataract in the hereditary retinal degenerations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383495

27 October 2018

Neurotrophic factors cause activation of intracellular signaling pathways in Müller cells and other cells of the inner retina, but not photoreceptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/16505355

12 December 2020

based on heuristic

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Survival and development in culture of dissociated parasympathetic neurons from ciliary ganglia

1 reference

https://pubmed.ncbi.nlm.nih.gov/16505355

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cholinergic neuronotrophic factors: I. Survival, neurite outgrowth and choline acetyltransferase activity in monolayer cultures from chick embryo ciliary ganglia

1 reference

https://pubmed.ncbi.nlm.nih.gov/16505355

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New visual acuity charts for clinical research

1 reference

https://pubmed.ncbi.nlm.nih.gov/16505355

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Standardization of vitreal inflammatory activity in intermediate and posterior uveitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16505355

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Photoreceptor degeneration in inherited retinal dystrophy delayed by basic fibroblast growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/16505355

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assessment of foveal cone photoreceptors in Stargardt's macular dystrophy using a small dot detection task

1 reference

https://pubmed.ncbi.nlm.nih.gov/16505355

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The pharmacokinetics of subcutaneously administered recombinant human ciliary neurotrophic factor (rHCNTF) in patients with amyotrophic lateral sclerosis: relation to parameters of the acute-phase response. The ALS CNTF Treatment Study (ACTS) Phase

1 reference

https://pubmed.ncbi.nlm.nih.gov/16505355

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A phase I study of recombinant human ciliary neurotrophic factor (rHCNTF) in patients with amyotrophic lateral sclerosis. The ALS CNTF Treatment Study (ACTS) Phase I-II Study Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/16505355

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retinopathy induced in mice by targeted disruption of the rhodopsin gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/16505355

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adenovirus-mediated gene transfer of ciliary neurotrophic factor can prevent photoreceptor degeneration in the retinal degeneration (rd) mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/16505355

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intravitreal interferon alpha-2b for the treatment of neovascular age-related macular degeneration: a pilot study

1 reference

https://pubmed.ncbi.nlm.nih.gov/16505355

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Complicated cataracts in various forms of retinitis pigmentosa. Type and incidence]

1 reference

https://pubmed.ncbi.nlm.nih.gov/16505355

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intraocular gene transfer of ciliary neurotrophic factor prevents death and increases responsiveness of rod photoreceptors in the retinal degeneration slow mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/16505355

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.0600236103

1 reference

Europe PubMed Central

2 August 2017

2006PNAS..103.3896S

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1 reference

Europe PubMed Central

2 August 2017

1 reference

Europe PubMed Central

2 August 2017

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