A discontinuous eight-amino acid epitope in human interleukin-3 binds the alpha-chain of its receptor. (Q34409307)

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21 October 2019

title

A discontinuous eight-amino acid epitope in human interleukin-3 binds the alpha-chain of its receptor (English)

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21 October 2019

5

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21 October 2019

author name string

C J Bagley

1

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21 October 2019

J Phillips

2

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21 October 2019

B Cambareri

3

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21 October 2019

M A Vadas

4

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21 October 2019

language of work or name

English

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publication date

1 December 1996

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Journal of Biological Chemistry

21 October 2019

published in

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21 October 2019

volume

271

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21 October 2019

issue

50

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21 October 2019

page(s)

31922-31928

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The human hematopoietic colony-stimulating factors

21 October 2019

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Interleukin 3 is a growth factor for human follicular B cell lymphoma

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The receptor for interleukin 3 is selectively induced in human endothelial cells by tumor necrosis factor alpha and potentiates interleukin 8 secretion and neutrophil transmigration

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A model for the interaction of the GM-CSF, IL-3 and IL-5 receptors with their ligands

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Saturation mutagenesis of human interleukin-3.

21 January 2018

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Structure-function relationships of interleukin-3. An analysis based on the function and binding characteristics of a series of interspecies chimera of gibbon and murine interleukin-3

21 January 2018

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A human interleukin 3 analog with increased biological and binding activities

21 January 2018

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Expression cloning of the human IL-3 receptor cDNA reveals a shared beta subunit for the human IL-3 and GM-CSF receptors

21 January 2018

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Molecular cloning of a second subunit of the receptor for human granulocyte-macrophage colony-stimulating factor (GM-CSF): reconstitution of a high-affinity GM-CSF receptor

21 January 2018

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A human high affinity interleukin-5 receptor (IL5R) is composed of an IL5-specific α chain and a β chain shared with the receptor for GM-CSF

21 January 2018

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Human interleukin-3 (IL-3) induces disulfide-linked IL-3 receptor alpha- and beta-chain heterodimerization, which is required for receptor activation but not high-affinity binding

21 January 2018

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Structure of the murine Jak2 protein-tyrosine kinase and its role in interleukin 3 signal transduction

21 January 2018

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JAK2 associates with the beta c chain of the receptor for granulocyte-macrophage colony-stimulating factor, and its activation requires the membrane-proximal region

21 January 2018

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Specific human granulocyte-macrophage colony-stimulating factor antagonists.

21 January 2018

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Human growth hormone and extracellular domain of its receptor: crystal structure of the complex

21 January 2018

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Novel fold and putative receptor binding site of granulocyte-macrophage colony-stimulating factor.

21 January 2018

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Cytokine conformations: Predictive studies

21 January 2018

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Role of disulfide bridges in determining the biological activity of interleukin 3.

21 January 2018

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PROCHECK: a program to check the stereochemical quality of protein structures

21 January 2018

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Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical features

21 January 2018

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Synthesis and expression of the gene encoding human interleukin-3.

21 January 2018

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Establishment and characterization of a unique human cell line that proliferates dependently on GM-CSF, IL-3, or erythropoietin

21 January 2018

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21 January 2018

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Raster3D Version 2.0. A program for photorealistic molecular graphics

21 January 2018

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[22] Iodine monochloride (ICI) iodination techniques

21 January 2018

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Specific binding, internalization, and degradation of human recombinant interleukin-3 by cells of the acute myelogenous, leukemia line, KG-1

21 January 2018

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1H, 13C, and 15N NMR resonance assignments, secondary structure, and backbone topology of a variant of human interleukin-3

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.271.50.31922

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8943237%20AND%20SRC:MED&resulttype=core&format=json

release_6pjmpe2wfzd7rfq6o3bm7qx3xi

21 October 2019

Fatcat ID

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Fatcat

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mapped directly with Wikidata item

24 November 2022

based on heuristic

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