Pharmacology of the neurotransmitter release enhancer linopirdine (DuP 996), and insights into its mechanism of action (Q34407516)

2 August 2017

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title

Pharmacology of the neurotransmitter release enhancer linopirdine (DuP 996), and insights into its mechanism of action (English)

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2 August 2017

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Aiken SP

1

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2 August 2017

Zaczek R

series ordinal

2

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2 August 2017

Brown BS

series ordinal

3

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2 August 2017

language of work or name

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1 January 1996

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2 August 2017

Advances in Pharmacology

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2 August 2017

35

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2 August 2017

349-384

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Reduction of spike frequency adaptation and blockade of M-current in rat CA1 pyramidal neurones by linopirdine (DuP 996), a neurotransmitter release enhancer

2 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960281-1

7 January 2021

Glucose, sulfonylureas, and neurotransmitter release: role of ATP-sensitive K+ channels.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960281-1

7 January 2021

Effects of linopirdine (DuP 996) and X9121 on age-related memory impairments and on the cholinergic system

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960281-1

7 January 2021

Ionic mechanisms of cholinergic excitation in mammalian hippocampal pyramidal cells

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960281-1

7 January 2021

An analysis of the depolarization produced in guinea-pig hippocampus by cholinergic receptor stimulation.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960281-1

7 January 2021

Fos immunoreactivity after stimulation or inhibition of muscarinic receptors indicates anatomical specificity for cholinergic control of striatal efferent neurons and cortical neurons in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960281-1

7 January 2021

Linopirdine (DuP996) facilitates the retention of avoidance training and improves performance of septal-lesioned rats in the water maze.

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https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960281-1

7 January 2021

M-currents: an update

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https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960281-1

7 January 2021

Muscarinic suppression of a novel voltage-sensitive K+ current in a vertebrate neurone

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960281-1

7 January 2021

Caffeine and theophylline analogues: correlation of behavioral effects with activity as adenosine receptor antagonists and as phosphodiesterase inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960281-1

7 January 2021

Reduced dopamine-beta-hydroxylase activity in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960281-1

7 January 2021

Subclasses of adenosine receptors in the central nervous system: Interaction with caffeine and related methylxanthines

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960281-1

7 January 2021

Selective loss of central cholinergic neurons in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960281-1

7 January 2021

Comparison of DuP 996, with physostigmine, THA and 3,4-DAP on hypoxia-induced amnesia in rats.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960281-1

7 January 2021

Effects of the memory enhancer linopirdine (Dup 996) on cerebral glucose metabolism in naive and hypoxia-exposed rats.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960281-1

7 January 2021

Classification of muscarinic responses in hippocampus in terms of receptor subtypes and second-messenger systems: electrophysiological studies in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960281-1

7 January 2021

The US economic and social costs of Alzheimer's disease revisited

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960281-1

7 January 2021

Interactions of D600 (methoxyverapamil) and local anesthetics with rat brain alpha-adrenergic and muscarinic receptors.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960281-1

7 January 2021

Alzheimer's disease and senile dementia: biochemical characteristics and aspects of treatment

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960281-1

7 January 2021

Membrane properties of cell types within guinea pig basal forebrain nuclei in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960281-1

7 January 2021

Memory impairments following basal forebrain lesions

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960281-1

7 January 2021

Muscarinic receptor-mediated induction of Fos protein in rat brain.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960281-1

7 January 2021

Properties of two calcium-activated hyperpolarizations in rat hippocampal neurones

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960281-1

7 January 2021

Control of the repetitive discharge of rat CA 1 pyramidal neurones in vitro.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960281-1

7 January 2021

Some Actions of 9-Amino-1,2,3,4-Tetrahydroacridine (THA) on Cholinergic Transmission and Membrane Currents in Rat Sympathetic Ganglia.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960281-1

7 January 2021

The potential for muscarinic receptor subtype-specific pharmacotherapy for Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960281-1

7 January 2021

The brain ryanodine receptor: A caffeine-sensitive calcium release channel

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960281-1

7 January 2021

DuP 996 (3,3-bis(4-pyrindinylmethyl)-1-phenylindolin-2-one) enhances the stimulus-induced release of acetylcholine from rat brain in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960281-1

7 January 2021

Blockers of voltage-gated K channels inhibit proliferation of cultured brown fat cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960281-1

7 January 2021

Agonists that suppress M-current elicit phosphoinositide turnover and Ca2+ transients, but these events do not explain M-current suppression

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960281-1

7 January 2021

Effect of the putative cognitive enhancer, linopirdine (DuP 996), on quantal parameters of acetylcholine release at the frog neuromuscular junction

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960281-1

7 January 2021

Local Cerebral Glucose Metabolism During Controlled Hypoxemia in Rats

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960281-1

7 January 2021

Kinetic and pharmacological properties of the M-current in rodent neuroblastoma x glioma hybrid cells

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960281-1

7 January 2021

Functional colocalization of calcium and calcium-gated potassium channels in control of transmitter release

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960281-1

7 January 2021

The effects of 4-aminopyridine and tetraethylammonium on the kinetics of transmitter release at the mammalian neuromuscular synapse

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960281-1

7 January 2021

EEG brain mapping in evaluating the time-course of the central action of DUP 996--a new acetylcholine releasing drug

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960281-1

7 January 2021

Taking stock of cognition enhancers

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https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960281-1

7 January 2021

Inhibition of the M current in NG 108-15 neuroblastoma x glioma hybrid cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960281-1

7 January 2021

Oral tetrahydroaminoacridine in long-term treatment of senile dementia, Alzheimer type.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960281-1

7 January 2021

Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960281-1

7 January 2021

Calcium channel antagonists induce direct inhibition of the outward rectifying potassium channel in tobacco protoplasts.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960281-1

7 January 2021

Dendrotoxin, 4-aminopyridine, and beta-bungarotoxin act at common loci but by two distinct mechanisms to induce Ca2+-dependent release of glutamate from guinea-pig cerebrocortical synaptosomes

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960281-1

7 January 2021

The effect of 3,3-dipyridylmethyl-1-phenyl-2-indolinone on the neuromuscular transmission in the rodent skeletal muscles

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960281-1

7 January 2021

Effects of 4-Aminopyridine in Elderly Patients with Alzheimer’s Disease

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960281-1

7 January 2021

Essential role of neocortical acetylcholine in spatial memory

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960281-1

7 January 2021

Unique properties of norepinephrine release from terminals arising from the locus coeruleus: high potassium sensitivity and lack of linopirdine (DuP 996) enhancement.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960281-1

7 January 2021

10.1016/S1054-3589(08)60281-1

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