CRR9/CLPTM1L regulates cell survival signaling and is required for Ras transformation and lung tumorigenesis (Q34394189)

25 June 2018

title

CRR9/CLPTM1L regulates cell survival signaling and is required for Ras transformation and lung tumorigenesis (English)

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25 June 2018

author name string

Michael A James

1

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25 June 2018

Haris G Vikis

2

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25 June 2018

Everett Tate

3

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25 June 2018

Amy L Rymaszewski

4

1 reference

25 June 2018

Ming You

5

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25 June 2018

language of work or name

English

0 references

publication date

23 December 2013

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25 June 2018

published in

Cancer Research

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25 June 2018

volume

74

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25 June 2018

issue

4

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25 June 2018

page(s)

1116-1127

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25 June 2018

CLPTM1L is overexpressed in lung cancer and associated with apoptosis

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TERT-CLPTM1L polymorphism rs401681 contributes to cancers risk: evidence from a meta-analysis based on 29 publications

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No association between TERT-CLPTM1L single nucleotide polymorphism rs401681 and mean telomere length or cancer risk

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Sequence variants at the TERT-CLPTM1L locus associate with many cancer types

6 July 2018

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Lung cancer susceptibility locus at 5p15.33

6 July 2018

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6 July 2018

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Gain at chromosomal region 5p15.33, containing TERT, is the most frequent genetic event in early stages of non-small cell lung cancer

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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A novel gene, CRR9, which was up-regulated in CDDP-resistant ovarian tumor cell line, was associated with apoptosis

6 July 2018

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K-ras codon 12 mutation induces higher level of resistance to apoptosis and predisposition to anchorage-independent growth than codon 13 mutation or proto-oncogene overexpression.

6 July 2018

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Regulation of Bcl-xL: a little bit of this and a little bit of STAT.

6 July 2018

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Activated Ras prevents downregulation of Bcl-X(L) triggered by detachment from the extracellular matrix. A mechanism of Ras-induced resistance to anoikis in intestinal epithelial cells

6 July 2018

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The Rel/NF-kappaB family directly activates expression of the apoptosis inhibitor Bcl-x(L).

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005686

Homozygous codeletion and differential decreased expression of p15INK4b, p16INK4a-alpha and p16INK4a-beta in mouse lung tumor cells.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005686

Multiple variants of TERT and CLPTM1L constitute risk factors for lung adenocarcinoma.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005686

Common genetic variants in TERT contribute to risk of cervical cancer in a Chinese population.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005686

Fine-mapping of a region of chromosome 5p15.33 (TERT-CLPTM1L) suggests a novel locus in TERT and a CLPTM1L haplotype are associated with glioma susceptibility in a Chinese population

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005686

The TERT-CLPTM1L lung cancer susceptibility variant associates with higher DNA adduct formation in the lung.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005686

Detachment-mediated resistance to TRAIL-induced apoptosis is associated with stimulation of the PI3K/Akt pathway in fetal and adenocarcinoma epithelial colon cells

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24366883

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/0008-5472.CAN-13-1617

1 reference

25 June 2018

PMCID

6005686

1 reference

25 June 2018

PubMed ID

24366883

1 reference

25 June 2018