Adenosine deaminase deficiency: metabolic basis of immune deficiency and pulmonary inflammation (Q34393135)

1 August 2017

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title

Adenosine deaminase deficiency: metabolic basis of immune deficiency and pulmonary inflammation (English)

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adenosine deaminase deficiency

1 August 2017

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Michael R Blackburn

1

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author name string

Rodney E Kellems

series ordinal

2

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1 August 2017

1 January 2005

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1 August 2017

Advances in Immunology

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1 August 2017

86

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1 August 2017

1-41

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Impaired Germinal Center Maturation in Adenosine Deaminase Deficiency

1 August 2017

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https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

The extracellular versus intracellular mechanisms of inhibition of TCR-triggered activation in thymocytes by adenosine under conditions of inhibited adenosine deaminase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Study of A(2A) adenosine receptor gene deficient mice reveals that adenosine analogue CGS 21680 possesses no A(2A) receptor-unrelated lymphotoxicity

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https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Adenosine deaminase deficiency increases thymic apoptosis and causes defective T cell receptor signaling

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https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Evidence for a complex regulatory array in the first intron of the human adenosine deaminase gene

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https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Canine mast cell adenosine receptors: cloning and expression of the A3 receptor and evidence that degranulation is mediated by the A2B receptor

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https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Effects of adrenergic agonists and adenosine on cholinergic neurotransmission in human tracheal smooth muscle

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https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Gene expression profiling in inflammatory airway disease associated with elevated adenosine

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https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Abnormal alveolar development associated with elevated adenine nucleosides

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https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

The cardiac effects of adenosine

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https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

p53 expression is required for thymocyte apoptosis induced by adenosine deaminase deficiency.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Too much of a good thing: adenosine overload in adenosine-deaminase-deficient mice

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https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Tissue-specific rescue suggests that placental adenosine deaminase is important for fetal development in mice

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https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Adenosine deaminase-deficient mice generated using a two-stage genetic engineering strategy exhibit a combined immunodeficiency

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

The use of enzyme therapy to regulate the metabolic and phenotypic consequences of adenosine deaminase deficiency in mice. Differential impact on pulmonary and immunologic abnormalities

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Metabolic consequences of adenosine deaminase deficiency in mice are associated with defects in alveogenesis, pulmonary inflammation, and airway obstruction

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Adenosine mediates IL-13-induced inflammation and remodeling in the lung and interacts in an IL-13-adenosine amplification pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

T lymphocyte-directed gene therapy for ADA- SCID: initial trial results after 4 years.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Brief report: hepatic dysfunction as a complication of adenosine deaminase deficiency

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Gene therapy in peripheral blood lymphocytes and bone marrow for ADA- immunodeficient patients

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Thymic morphology in immunodeficiency diseases: Results of thymic biopsies

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Human severe combined immunodeficiency: genetic, phenotypic, and functional diversity in one hundred eight infants

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Hairy-cell leukaemia as a model for drug development

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

The chondro-osseous dysplasia of adenosine deaminase deficiency with severe combined immunodeficiency

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

A(2A) adenosine receptor deficiency attenuates brain injury induced by transient focal ischemia in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Developmental expression of adenosine deaminase in the upper alimentary tract of mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Adenosine-dependent airway inflammation and hyperresponsiveness in partially adenosine deaminase-deficient mice

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https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Adenosine: an endogenous regulator of innate immunity

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https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Inhaled adenosine and guanosine on airway resistance in normal and asthmatic subjects

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Protection from ischemic liver injury by activation of A2A adenosine receptors during reperfusion: inhibition of chemokine induction

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Restricted heterogeneity of T lymphocytes in combined immunodeficiency with hypereosinophilia (Omenn's syndrome).

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Association of HLA class I antigen deficiency related to a TAP2 gene mutation with familial bronchiectasis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Adenosine in bronchoalveolar lavage fluid in asthma

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https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Regulation of duodenal specific expression of the human adenosine deaminase gene.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Airway remodeling in asthma

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https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Role of endogenous adenosine in the acute and late response to allergen challenge in actively sensitized Brown Norway rats

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https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Adenosine-mediated bronchoconstriction and lung inflammation in an allergic mouse model

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Inhibition of human mast cell activation with the novel selective adenosine A(2B) receptor antagonist 3-isobutyl-8-pyrrolidinoxanthine (IPDX)(2).

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Adenosine acts as a chemoprotective agent by stimulating G-CSF production: a role for A1 and A3 adenosine receptors

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https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Adenosine, mast cells and asthma

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https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Adenosine receptor ligands: potential as therapeutic agents in asthma and COPD.

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https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

How does adenosine inhibit transmitter release?

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https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Tolerance of NK and LAK activity for HLA class I-deficient targets in a TAP1-deficient patient (bare lymphocyte syndrome type I)

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https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Adenosine-deaminase deficiency in two patients with severely impaired cellular immunity

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https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Nucleoside-phosphorylase deficiency in a child with severely defective T-cell immunity and normal B-cell immunity

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https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Defective expression of p56lck in an infant with severe combined immunodeficiency

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https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

A role for mast cells in adenosine A3 receptor-mediated hypotension in the rat

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https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Mechanism of airway hyperresponsiveness to adenosine induced by allergen challenge in actively sensitized Brown Norway rats

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https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

PEG-ADA replacement therapy for adenosine deaminase deficiency: an update after 8.5 years

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https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Genotype is an important determinant of phenotype in adenosine deaminase deficiency

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

In vivo inactivation of erythrocyte S-adenosylhomocysteine hydrolase by 2'-deoxyadenosine in adenosine deaminase-deficient patients

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Adenosine deaminase activity in normal tissues and tissues from a child with severe combined immunodeficiency and adenosine deaminase deficiency

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https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Amerioration of neurologic abnormalities after "enzyme replacement" in adenosine deaminase deficiency

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https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Spontaneous in vivo reversion to normal of an inherited mutation in a patient with adenosine deaminase deficiency

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Adenosine in exhaled breath condensate in healthy volunteers and in patients with asthma

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Inosine binds to A3 adenosine receptors and stimulates mast cell degranulation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Adenosine-induced secretion in the canine trachea: modification by methylxanthines and adenosine derivatives

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https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Direct association of adenosine deaminase with a T cell activation antigen, CD26

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Elevation of serum IgE level and peripheral eosinophil count during T lymphocyte-directed gene therapy for ADA deficiency: implication of Tc2-like cells after gene transduction procedure.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Major histocompatibility complex class II deficiency: clinical manifestations, immunologic features, and outcome

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https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Ontogeny of adenosine deaminase in the mouse decidua and placenta: immunolocalization and embryo transfer studies

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

T lymphocytes with a normal ADA gene accumulate after transplantation of transduced autologous umbilical cord blood CD34+ cells in ADA-deficient SCID neonates.

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https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

S -Adenosylhomocysteine toxicity in normal and adenosine kinase-deficient lymphoblasts of human origin

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https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Adenosine A1 receptor mediated protection of the globally ischemic isolated rat heart

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Adenosine in the central nervous system: release mechanisms and extracellular concentrations

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Induction of an apoptotic program in cell-free extracts by 2-chloro-2'-deoxyadenosine 5'-triphosphate and cytochrome c

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Adenosine deaminase deficiency with late onset of recurrent infections: response to treatment with polyethylene glycol-modified adenosine deaminase

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https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Mast-cell growth and differentiation

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https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Molecular approach to adenosine receptors: receptor-mediated mechanisms of tissue protection

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https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Subclasses of external adenosine receptors

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https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Periventricular leukomalacia: relationship between lateral ventricular volume on brain MR images and severity of cognitive and motor impairment

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Adenosine-deaminase-deficient mice die perinatally and exhibit liver-cell degeneration, atelectasis and small intestinal cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

The structure and function of CD26 in the T-cell immune response

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Interleukin-2 receptor gamma chain mutation results in X-linked severe combined immunodeficiency in humans

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

DNA antisense therapy for asthma in an animal model

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

2'-Deoxycoformycin (pentostatin) for lymphoid malignancies. Rational development of an active new drug

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Role of G-protein-coupled adenosine receptors in downregulation of inflammation and protection from tissue damage

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Adenosine receptor subtypes: characterization and therapeutic regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Airway responsiveness to adenosine 5'-monophosphate in chronic obstructive pulmonary disease is determined by smoking

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

S-adenosylhomocysteine as a physiological modulator of Apo-1-mediated apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Adenosine A3 receptors promote degranulation of rat mast cells both in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

The binding site of human adenosine deaminase for CD26/Dipeptidyl peptidase IV: the Arg142Gln mutation impairs binding to cd26 but does not cause immune deficiency

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Disruption of the A(3) adenosine receptor gene in mice and its effect on stimulated inflammatory cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Novel splicing, missense, and deletion mutations in seven adenosine deaminase-deficient patients with late/delayed onset of combined immunodeficiency disease. Contribution of genotype to phenotype

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

RAG mutations in human B cell-negative SCID.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Mechanism of deoxyadenosine and 2-chlorodeoxyadenosine toxicity to nondividing human lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Diverse Genetic Regulatory Motifs Required for Murine Adenosine Deaminase Gene Expression in the Placenta

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Severe combined immunodeficiency: a retrospective single-center study of clinical presentation and outcome in 117 patients

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Mediation of tubuloglomerular feedback by adenosine: evidence from mice lacking adenosine 1 receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Metabolites from apoptotic thymocytes inhibit thymopoiesis in adenosine deaminase-deficient fetal thymic organ cultures

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Airway hyperresponsiveness to adenosine induced by lipopolysaccharide in Brown Norway rats

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Adenosine and inosine increase cutaneous vasopermeability by activating A(3) receptors on mast cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

A1 adenosine receptor activation induces ventriculomegaly and white matter loss

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

A1 adenosine receptors mediate hypoxia-induced ventriculomegaly

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Deoxyadenosine metabolism and cytotoxicity in cultured mouse T lymphoma cells: a model for immunodeficiency disease

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Isolation and characterization of purine-nucleoside phosphorylase-deficient T-lymphoma cells and secondary mutants with altered ribonucleotide reductase: Genetic model for immunodeficiency disease

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Neurobiology of periventricular leukomalacia in the premature infant

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Disruption of the adenosine deaminase gene causes hepatocellular impairment and perinatal lethality in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Adenosine A3 receptor expression and function in eosinophils.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Coordinate developmental regulation of purine catabolic enzyme expression in gastrointestinal and postimplantation reproductive tracts

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Regulation of forestomach-specific expression of the murine adenosine deaminase gene.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

dATP causes specific release of cytochrome C from mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

A3 adenosine receptor signaling contributes to airway inflammation and mucus production in adenosine deaminase-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Activation of murine lung mast cells by the adenosine A3 receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

IL-13-induced chemokine responses in the lung: role of CCR2 in the pathogenesis of IL-13-induced inflammation and remodeling

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

Lung development in the mouse embryo

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2986001-2

7 January 2021

10.1016/S0065-2776(04)86001-2

Identifiers

DOI

1 reference

1 August 2017

1 reference

PubMed ID

15705418