Macrolides: structures and microbial targets (Q34382775)

1 August 2017

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title

Macrolides: structures and microbial targets (English)

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1 August 2017

Retsema J

1

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PubMed ID

11574188

1 August 2017

Fu W

series ordinal

2

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1 August 2017

1 January 2001

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International Journal of Antimicrobial Agents

1 August 2017

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1 August 2017

18 Suppl 1

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1 August 2017

S3-10

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New research in macrolides and ketolides since 1997.

1 August 2017

1 reference

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Azithromycin. A review of its antimicrobial activity, pharmacokinetic properties and clinical efficacy

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Quantitative structure-activity relationships among macrolide antibacterial agents: in vitro and in vivo potency against Pasteurella multocida.

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Effect of erythromycin analogues on binding of [14C]erythromycin to Escherichia coli ribosomes

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Synthesis, in vitro and in vivo activity of novel 9-deoxo-9a-AZA-9a-homoerythromycin A derivatives; a new class of macrolide antibiotics, the azalides

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Synthesis and antibacterial activity of HMR 3647 a new ketolide highly potent against erythromycin-resistant and susceptible pathogens

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7 January 2021

Recent developments in macrolides and ketolides

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Mechanism of action of streptogramins and macrolides

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The macrolide-ketolide antibiotic binding site is formed by structures in domains II and V of 23S ribosomal RNA.

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Structure-activity studies of tylosin-related macrolides

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7 January 2021

Evaluation of three 4"-deoxy-4"-sulfonamido-oleandomycin derivatives with erythromycin-like antibacterial potency

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Spectrum and mode of action of azithromycin (CP-62,993), a new 15-membered-ring macrolide with improved potency against gram-negative organisms

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7 January 2021

Molecular cloning and functional analysis of a novel macrolide-resistance determinant, mefA, from Streptococcus pyogenes.

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Placement of protein and RNA structures into a 5 A-resolution map of the 50S ribosomal subunit

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Streptococcus pneumoniae and Streptococcus pyogenes resistant to macrolides but sensitive to clindamycin: a common resistance pattern mediated by an efflux system

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mefE is necessary for the erythromycin-resistant M phenotype in Streptococcus pneumoniae.

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7 January 2021

Novel mechanism of macrolide resistance in Streptococcus pneumoniae

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7 January 2021

The emergence of Streptococcus pneumoniae resistant to macrolide antimicrobial agents: a 6-year population-based assessment

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Prevalence of macrolide resistance mechanisms in Streptococcus pneumoniae isolates from a multicenter antibiotic resistance surveillance study conducted in the United States in 1994-1995.

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Gene localization, size, and physical map of the chromosome of Streptococcus pneumoniae

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Ribosomal drug resistance in mycobacteria

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Macrolide resistance and erythromycin resistance determinants among Belgian Streptococcus pyogenes and Streptococcus pneumoniae isolates.

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Patterns of macrolide resistance determinants among community-acquired Streptococcus pneumoniae isolates over a 5-year period of decreased macrolide susceptibility rates.

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Distribution of mefE and ermB genes in macrolide-resistant strains of Streptococcus pneumoniae and their variable susceptibility to various antibiotics

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Phenotypes and genotypes of erythromycin-resistant Streptococcus pyogenes strains in Italy and heterogeneity of inducibly resistant strains

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High prevalence of erythromycin-resistant, clindamycin/miocamycin-susceptible (M phenotype) Streptococcus pyogenes: results of a Spanish multicentre study in 1998. Spanish Group for the Study of Infection in the Primary Health Care Setting

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Mutations in 23S rRNA are associated with clarithromycin resistance in Helicobacter pylori.

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Mutations in 23S rRNA and ribosomal protein L4 account for resistance in pneumococcal strains selected in vitro by macrolide passage

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In vitro development of resistance to telithromycin (HMR 3647), four macrolides, clindamycin, and pristinamycin in Streptococcus pneumoniae

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A new ketolide, HMR 3004, active against streptococci inducibly resistant to erythromycin

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Induction of ribosome methylation in MLS-resistant Streptococcus pneumoniae by macrolides and ketolides.

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7 January 2021

In vitro activity of the new ketolide telithromycin compared with those of macrolides against Streptococcus pyogenes: influences of resistance mechanisms and methodological factors

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The role of newer macrolides in the treatment of community-acquired respiratory tract infection. A review of experimental and clinical data

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Community-acquired pneumonia in ambulatory patients: relative importance of atypical pathogens

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Treatment of community-acquired pneumonia in hospitalised patients

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The place of antibiotic therapy in the management of chronic acute exacerbations of chronic bronchitis

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Worldwide guidelines for respiratory tract infections: community-acquired pneumonia

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Japanese guidelines for the management of community-acquired pneumonia

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7 January 2021

Non-antimicrobial activities of macrolides

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7 January 2021

10.1016/S0924-8579(01)00401-0

Identifiers

DOI

1 reference

1 August 2017

1 reference

PubMed ID

11574188