Omeprazole inhibits colorectal carcinogenesis induced by azoxymethane in rats (Q34377608)

1 August 2017

Omeprazole inhibits colorectal carcinogenesis induced by azoxymethane in rats (English)

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1 August 2017

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Penman ID

1

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1 August 2017

el-Omar E

2

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1 August 2017

McGregor JR

3

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1 August 2017

Hillan KJ

4

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1 August 2017

O'Dwyer PJ

5

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1 August 2017

McColl KE

6

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1 August 2017

language of work or name

English

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publication date

1 November 1993

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1 August 2017

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1 August 2017

34

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1 August 2017

11

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1 August 2017

1559-1565

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Dimethylhydrazine-induced colonic neoplasia: dissociation from endogenous gastrin levels

1 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1374422

Evaluation of the effects of pentagastrin, gastrin and pancreatic glucagon on cell proliferation in the rat gastrointestinal tract.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1374422

Optimal dose of oral omeprazole for maximal 24 hour decrease of intragastric acidity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1374422

Intragastric bacterial activity and nitrosation before, during, and after treatment with omeprazole

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1374422

Enhancement and inhibition of the induction by 7,12-dimethylbenz(a)anthracene of mammary tumours in female Sprague-Dawley rats

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1374422

Inhibition of the carcinogenic action of benzo(a)pyrene by flavones

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1374422

Gastrin has no promoting effect on chemically induced colonic tumors in Wistar rats.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1374422

Pentagastrin stimulates in vitro growth of normal and malignant human colon epithelial cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1374422

Gastrin stimulates growth of colon cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1374422

Toxicological studies on omeprazole

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1374422

Roles of cytochrome P-450 enzymes in chemical carcinogenesis and cancer chemotherapy.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1374422

Proglumide, a gastrin receptor antagonist, inhibits growth of colon cancer and enhances survival in mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1374422

Elevated gastrin levels in patients with colon cancer or adenomatous polyps.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1374422

Clinical significance of gastrin receptors in human colon cancers.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1374422

Role of gastrin/pentagastrin in regulation of intestinal cytochrome P-450.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1374422

Human cytochrome P450 isoforms. Their genetic heterogeneity and induction by omeprazole

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1374422

Effect of long-term treatment with omeprazole on serum gastrin and serum group A and C pepsinogens in patients with reflux esophagitis.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1374422

Omeprazole is an aryl hydrocarbon-like inducer of human hepatic cytochrome P450.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1374422

Intracellular gastrin in human gastrointestinal tumor cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1374422

Expression of two cytochromes P450 involved in carcinogen activation in a human colon cell line

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1374422

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1374422

Influence of gastrin, gastrin receptor blockers, epidermal growth factor, and difluoromethylornithine on the growth and the activity of ornithine decarboxylase of colonic carcinoma cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1374422

Metabolism of azoxymethane, methylazoxymethanol and N-nitrosodimethylamine by cytochrome P450IIE1.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1374422

Human cytochromes P450: evolution, catalytic activities and interindividual variations in expression

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1374422

Metabolic activation of carcinogenic heterocyclic aromatic amines by human liver and colon

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1374422

Inhibitory effects of the gastrin receptor antagonist (L-365,260) on gastrointestinal tumor cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1374422

Effect of omeprazole-induced hypergastrinaemia on the proliferation of colonic mucosal epithelial cells in the rat.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1374422

Co-stimulation of gastrointestinal tumour cell growth by gastrin, transforming growth factor α and insulin like growth factor-I

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1374422

Postprandial hypergastrinaemia in patients with colorectal cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1374422

Effects of the food mutagens MeIQx and PhIP on the expression of cytochrome P450IA proteins in various tissues of male and female rats.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1374422

Detection and characterization of the Ah receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin in the human colon adenocarcinoma cell line LS180

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1374422

Modulation of the levels of cytochromes P450 in rat liver and lung by dietary lipid

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1374422

Serum gastrin concentrations in colorectal cancer patients

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1374422

Measurement of gastrin and transforming growth factor alpha messenger RNA levels in colonic carcinoma cell lines by quantitative polymerase chain reaction

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1374422

Serum gastrin levels in colorectal cancers. Evolution after treatment

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1374422

Trophic effect of gastrin on the enterochromaffin like cells of the rat stomach: establishment of a dose response relationship

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1374422

Omeprazole, cytochrome P450, and chemical carcinogenesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1374422

Compensatory postresectional hyperplasia and starvation atrophy in small bowel: dissociation from endogenous gastrin levels

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1374422

New aspects of the trophic action of gastrointestinal hormones

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1374422

Promotion of azoxymethane-induced colonic neoplasia by resection of the proximal small bowel

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1374422

2 Radioimmunoassay of GI hormones

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1374422

Colon carcinogenesis with azoxymethane and dimethylhydrazine in germ-free rats

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1374422

On the protective action of certain polycyclic aromatic hydrocarbons against carcinogenesis by aminoazo dyes and 2-acetylaminofluorene.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1374422

Serum gastrin response to feeding in achlorhydric patients.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1374422

Total calories, body weight, and tumor incidence in mice.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1374422

Trophic Effects of Gastrin on Colorectal Neoplasms in the Rat

27 October 2018

1 reference

12 December 2020

Induction of cytochrome P450IA genes (CYP1A) by omeprazole in the human alimentary tract

1 reference

12 December 2020

Pathological features of the colonic tumours induced in rats by the administration of 1,2-dimethylhydrazine

1 reference

12 December 2020

Tissue-specific induction of the carcinogen inducible cytochrome P450 isoform, P450IAI, in colonic epithelium

1 reference

12 December 2020

In vitro responsiveness of human gastric carcinoma to pentagastrin

1 reference

12 December 2020

The in vitro growth response of primary human colorectal and gastric cancer cells to gastrin

1 reference

12 December 2020

Protection against tumorigenesis by 3-methylcholanthrene in mice by beta-naphthoflavone as a function of inducibility of methylcholanthrene metabolism

1 reference

12 December 2020

Growth-promoting action of gastrin on human colonic and gastric tumour cells cultured in vitro

1 reference

12 December 2020

Effect of different levels of calorie restriction on azoxymethane-induced colon carcinogenesis in male F344 rats

1 reference

12 December 2020

Gastrin receptors in normal and malignant gastrointestinal mucosa: age-associated changes

1 reference

12 December 2020

Effects of gastrin, proglumide, and somatostatin on growth of human colon cancer

1 reference

12 December 2020

Omeprazole and the induction of human cytochrome P-450: a response to concerns about potential adverse effects

1 reference

12 December 2020

Hypergastrinemia and colorectal carcinogenesis in the rat

1 reference

12 December 2020

Induction of cytochrome P-450IA1, IA2, IIB1, IIB2 and IIE1 by broccoli in rat liver and colon

1 reference

12 December 2020

The H+,K+-ATPase inhibitor pantoprazole (BY1023/SK&F96022) interacts less with cytochrome P450 than omeprazole and lansoprazole

1 reference

12 December 2020

Influence of caloric restriction and exercise on tumorigenesis in rats

1 reference

12 December 2020

Omeprazole-induced hypergastrinemia does not influence growth of colon carcinoma

1 reference

12 December 2020

Characterization of cytochrome P450-dependent dimethylhydrazine metabolism in human colon microsomes

1 reference

12 December 2020

Enterochromaffin-like cell carcinoids of gastric mucosa in rats after life-long inhibition of gastric secretion

1 reference

12 December 2020

Identifiers

DOI

10.1136/GUT.34.11.1559

1 reference

1 August 2017

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1 August 2017

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