Chloride extrusion enhancers as novel therapeutics for neurological diseases (Q34375595)

1 August 2017

title

Chloride extrusion enhancers as novel therapeutics for neurological diseases (English)

1 reference

1 August 2017

Annie Castonguay

4

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Robert P. Bonin

object named as

Robert P Bonin

6

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Yves De Koninck

object named as

Yves De Koninck

19

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author name string

Martin Gagnon

1

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1 August 2017

Marc J Bergeron

2

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1 August 2017

Guillaume Lavertu

3

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1 August 2017

Sasmita Tripathy

5

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1 August 2017

Jimena Perez-Sanchez

7

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1 August 2017

Dominic Boudreau

8

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1 August 2017

Bin Wang

9

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1 August 2017

Lionel Dumas

10

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1 August 2017

Isabelle Valade

11

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1 August 2017

Karine Bachand

12

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1 August 2017

Mariève Jacob-Wagner

13

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1 August 2017

Christian Tardif

14

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1 August 2017

Irenej Kianicka

15

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1 August 2017

Paul Isenring

16

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1 August 2017

Giorgio Attardo

17

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1 August 2017

Jeffrey A M Coull

18

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1 August 2017

language of work or name

English

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publication date

6 October 2013

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1 August 2017

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1 August 2017

volume

19

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1 August 2017

issue

11

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1 August 2017

page(s)

1524-1528

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describes a project that uses

1 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4005788/fullTextXML

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/nm.3356

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cites work

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Activation of 5-HT2A receptors upregulates the function of the neuronal K-Cl cotransporter KCC2.

6 July 2018

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6 July 2018

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Antiepileptic drugs for the treatment of neuropathic pain: a systematic review

6 July 2018

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Efficacy of synaptic inhibition depends on multiple, dynamically interacting mechanisms implicated in chloride homeostasis

6 July 2018

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Upregulation of KCC2 activity by zinc-mediated neurotransmission via the mZnR/GPR39 receptor

6 July 2018

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6 July 2018

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6 July 2018

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Altered expression of regulators of the cortical chloride transporters NKCC1 and KCC2 in schizophrenia

6 July 2018

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6 July 2018

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Small-molecule screen identifies inhibitors of the neuronal K-Cl cotransporter KCC2

6 July 2018

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The role of cation-dependent chloride transporters in neuropathic pain following spinal cord injury

6 July 2018

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Roles of the cation-chloride cotransporters in neurological disease.

6 July 2018

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The RCC1 domain of protein associated with Myc (PAM) interacts with and regulates KCC2

6 July 2018

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Allodynia and hyperalgesia in diabetic rats are mediated by GABA and depletion of spinal potassium-chloride co-transporters

6 July 2018

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6 July 2018

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Gabapentin and pregabalin for chronic neuropathic and early postsurgical pain: current evidence and future directions

6 July 2018

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Homooligomeric and heterooligomeric associations between K+-Cl- cotransporter isoforms and between K+-Cl- and Na+-K+-Cl- cotransporters.

6 July 2018

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Altered chloride homeostasis in neurological disorders: a new target

6 July 2018

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BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain

6 July 2018

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Brain-type creatine kinase activates neuron-specific K+-Cl- co-transporter KCC2

6 July 2018

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Role of cation-chloride-cotransporters (CCC) in pain and hyperalgesia

6 July 2018

1 reference

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Behavioural phenotypes of hypomorphic KCC2-deficient mice

6 July 2018

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Mechanism of activity-dependent downregulation of the neuron-specific K-Cl cotransporter KCC2.

6 July 2018

1 reference

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Trans-synaptic shift in anion gradient in spinal lamina I neurons as a mechanism of neuropathic pain

6 July 2018

1 reference

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BDNF-induced TrkB activation down-regulates the K+-Cl- cotransporter KCC2 and impairs neuronal Cl- extrusion

6 July 2018

1 reference

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Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

6 July 2018

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Cloning, characterization, and chromosomal location of a novel human K+-Cl- cotransporter

6 July 2018

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Quantitative assessment of tactile allodynia in the rat paw

6 July 2018

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A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man.

6 July 2018

1 reference

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Down-regulation of the potassium-chloride cotransporter KCC2 contributes to spasticity after spinal cord injury

6 July 2018

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Altered chloride homeostasis removes synaptic inhibitory constraint of the stress axis

21 January 2018

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Perturbed chloride homeostasis and GABAergic signaling in human temporal lobe epilepsy.

21 January 2018

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Spinal cord injury-induced attenuation of GABAergic inhibition in spinal dorsal horn circuits is associated with down-regulation of the chloride transporter KCC2 in rat.

21 January 2018

1 reference

Expression of the neuron-specific potassium chloride cotransporter KCC2 in adult rat cochlear

21 January 2018

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Electroneutral cation-chloride cotransporters in the central nervous system

21 January 2018

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The neuropathic pain market

21 January 2018

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A mechanism for Ca2+/calmodulin-dependent protein kinase II clustering at synaptic and nonsynaptic sites based on self-association.

21 January 2018

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Pharmacological enhancement of δ-subunit-containing GABA(A) receptors that generate a tonic inhibitory conductance in spinal neurons attenuates acute nociception in mice.

21 January 2018

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Differential maturation of GABA action and anion reversal potential in spinal lamina I neurons: impact of chloride extrusion capacity.

21 January 2018

1 reference

Reduced potassium-chloride co-transporter expression in spinal cord dorsal horn neurons contributes to inflammatory pain hypersensitivity in rats

21 January 2018

1 reference

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Fixed-diameter polyethylene cuffs applied to the rat sciatic nerve induce a painful neuropathy: ultrastructural morphometric analysis of axonal alterations

27 October 2018

1 reference

12 December 2020

Nerve constriction in the rat: model of neuropathic, surgical and central pain

1 reference

12 December 2020

A genetically encoded ratiometric indicator for chloride: capturing chloride transients in cultured hippocampal neurons

1 reference

12 December 2020

The differential expression patterns of messenger RNAs encoding K-Cl cotransporters (KCC1,2) and Na-K-2Cl cotransporter (NKCC1) in the rat nervous system

1 reference

12 December 2020

Identifiers

DOI

10.1038/NM.3356

1 reference

1 August 2017

1 reference

1 August 2017

1 reference