Selective small molecule Stat3 inhibitor reduces breast cancer tumor-initiating cells and improves recurrence free survival in a human-xenograft model. (Q34373888)

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English	Selective small molecule Stat3 inhibitor reduces breast cancer tumor-initiating cells and improves recurrence free survival in a human-xenograft model.	scientific article

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10 February 2020

Selective small molecule Stat3 inhibitor reduces breast cancer tumor-initiating cells and improves recurrence free survival in a human-xenograft model (English)

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10 February 2020

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10 February 2020

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Bhuvanesh Dave

1

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10 February 2020

Melissa D Landis

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10 February 2020

David J Tweardy

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10 February 2020

Lacey E Dobrolecki

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10 February 2020

Meng-Fen Wu

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10 February 2020

Xiaomei Zhang

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10 February 2020

Thomas F Westbrook

8

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10 February 2020

Susan G Hilsenbeck

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10 February 2020

Dan Liu

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10 February 2020

Michael T Lewis

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6 August 2012

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10 February 2020

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10 February 2020

e30207

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10 February 2020

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Creative Commons Attribution 4.0 International

6 August 2012

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Protein tyrosine phosphatases, TC-PTP, SHP1, and SHP2, cooperate in rapid dephosphorylation of Stat3 in keratinocytes following UVB irradiation

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Glioblastoma cancer-initiating cells inhibit T-cell proliferation and effector responses by the signal transducers and activators of transcription 3 pathway

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CXCR1 blockade selectively targets human breast cancer stem cells in vitro and in xenografts

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Targeting breast stem cells with the cancer preventive compounds curcumin and piperine

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Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features

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6 July 2018

Chemical probes that competitively and selectively inhibit Stat3 activation

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6 July 2018

Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy

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6 July 2018

Stat3 isoforms, alpha and beta, demonstrate distinct intracellular dynamics with prolonged nuclear retention of Stat3beta mapping to its unique C-terminal end.

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6 July 2018

Selective chemical probe inhibitor of Stat3, identified through structure-based virtual screening, induces antitumor activity

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6 July 2018

STAT3: a critical transcription activator in angiogenesis.

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6 July 2018

Molecular definition of breast tumor heterogeneity

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6 July 2018

Stem cells in mammary development and carcinogenesis: implications for prevention and treatment

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6 July 2018

Targeting transcription factors for cancer therapy

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G-quartet oligonucleotides: a new class of signal transducer and activator of transcription 3 inhibitors that suppresses growth of prostate and breast tumors through induction of apoptosis

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Stem cells in normal breast development and breast cancer

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Prospective identification of tumorigenic breast cancer cells

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STAT proteins: novel molecular targets for cancer drug discovery

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Complex roles of Stat1 in regulating gene expression

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Three-dimensional structure of the Stat3beta homodimer bound to DNA

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6 July 2018

STAT3 is essential for the maintenance of neurosphere-initiating tumor cells in patients with glioblastomas: a potential for targeted therapy?

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27 October 2018

Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells

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Estrogen-receptor-alpha exchange and chromatin dynamics are ligand- and domain-dependent

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12 December 2020

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10.1371/JOURNAL.PONE.0030207

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10 February 2020

2012PLoSO...730207D

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10 February 2020

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10 February 2020

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