Synthetic allergen design reveals the significance of moderate affinity epitopes in mast cell degranulation. (Q34373086)

1 August 2017

title

Synthetic allergen design reveals the significance of moderate affinity epitopes in mast cell degranulation. (English)

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1 August 2017

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N(alpha),N(tele)-(Dnp)2-His-Gln

ChEBI ID

72496

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ChEBI ID

72494

fluorescein-DNP hapten

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2

Tanyel Kiziltepe

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1 August 2017

4

Basar Bilgicer

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1 August 2017

Michael W Handlogten

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1 August 2017

Nathan J Alves

series ordinal

3

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1 August 2017

publication date

21 August 2012

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1 August 2017

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1 August 2017

volume

7

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1 August 2017

issue

11

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1 August 2017

page(s)

1796-1801

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Design of a heterobivalent ligand to inhibit IgE clustering on mast cells

1 August 2017

cites work

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6 July 2018

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Nanoparticle-mediated IgE-receptor aggregation and signaling in RBL mast cells

6 July 2018

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Small, mobile FcepsilonRI receptor aggregates are signaling competent

6 July 2018

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The RBL-2H3 cell line: its provenance and suitability as a model for the mast cell

6 July 2018

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Mapping of the IgE and IgG4 sequential epitopes of milk allergens with a peptide microarray-based immunoassay

6 July 2018

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Several distinct properties of the IgE repertoire determine effector cell degranulation in response to allergen challenge

6 July 2018

1 reference

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Mimotope mapping as a complementary strategy to define allergen IgE-epitopes: peach Pru p 3 allergen as a model

6 July 2018

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Trivalent ligands with rigid DNA spacers reveal structural requirements for IgE receptor signaling in RBL mast cells

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Statistical pattern matching facilitates the design of polyvalent inhibitors of anthrax and cholera toxins

6 July 2018

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6 July 2018

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Highly Effective Poly(Ethylene Glycol) Architectures for Specific Inhibition of Immune Receptor Activation

6 July 2018

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6 July 2018

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Molecular cloning and epitope analysis of the peanut allergen Ara h 3.

6 July 2018

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Simultaneous cross-linking by two nontriggering bivalent ligands causes synergistic signaling of IgE Fc epsilon RI complexes.

6 July 2018

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Possible orientational constraints determine secretory signals induced by aggregation of IgE receptors on mast cells

6 July 2018

1 reference

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Transmembrane signaling: the joy of aggregation

6 July 2018

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Mapping and conformational analysis of IgE-binding epitopic regions on the molecular surface of the major Ara h 3 legumin allergen of peanut (Arachis hypogaea).

6 July 2018

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Assays for regulated exocytosis of mast cell granules

27 October 2018

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The specificity of cross‐reactivity: Promiscuous antibody binding involves specific hydrogen bonds rather than nonspecific hydrophobic stickiness

27 October 2018

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Activating B Cell Signaling with Defined Multivalent Ligands

27 October 2018

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A quantitative approach for studying IgE-FcepsilonRI aggregation

9 December 2018

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12 December 2020

Antigen-dependent transition of IgE to a detergent-insoluble form is associated with reduced IgE receptor-dependent secretion from RBL-2H3 mast cells

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12 December 2020

Immunoglobulin-E-binding epitopes of wheat allergens in patients with food allergy to wheat and in mice experimentally sensitized to wheat proteins

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12 December 2020

Polyvalent Interactions in Biological Systems: Implications for Design and Use of Multivalent Ligands and Inhibitors

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12 December 2020

Antigen valency as a determinant of the responsiveness of IgE-sensitised rat basophil leukemia cells

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12 December 2020

Rat basophil leukaemia (RBL) cells sensitized with low affinity IgE respond to high valency antigen

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12 December 2020

Kinetics of multivalent antigen DNP-BSA binding to IgE-Fc epsilon RI in relationship to the stimulated tyrosine phosphorylation of Fc epsilon RI

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12 December 2020

Comparisons of the ability of human IgG3 hinge mutants, IgM, IgE, and IgA2, to form small immune complexes: a role for flexibility and geometry

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12 December 2020

Identifiers

DOI

10.1021/CB300193F

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1 August 2017

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1 August 2017

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