Identification of the MMRN1 binding region within the C2 domain of human factor V. (Q34353691)

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3 January 2020

title

Identification of the MMRN1 binding region within the C2 domain of human factor V (English)

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1

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Catherine Hayward

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author name string

Rachael A Woram

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Nola Fuller

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Mary Ann Quinn-Allen

4

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Gerry A F Nicolaes

5

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Bjorn Dahlbäck

6

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William H Kane

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language of work or name

English

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publication date

27 September 2004

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Journal of Biological Chemistry

3 January 2020

published in

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volume

279

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issue

49

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page(s)

51466-51471

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Factor V and thrombotic disease: description of a janus-faced protein

3 January 2020

cites work

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The C-terminal region of the factor V B-domain is crucial for the anticoagulant activity of factor V.

21 January 2018

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Removal of B-domain sequences from factor V rather than specific proteolysis underlies the mechanism by which cofactor function is realized

21 January 2018

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Posttranslational sulfation of factor V is required for efficient thrombin cleavage and activation and for full procoagulant activity

21 January 2018

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Factor V is complexed with multimerin in resting platelet lysates and colocalizes with multimerin in platelet alpha-granules

21 January 2018

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Unique in vivo modifications of coagulation factor V produce a physically and functionally distinct platelet-derived cofactor: characterization of purified platelet-derived factor V/Va

21 January 2018

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Structural requirements for expression of factor Va activity

21 January 2018

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The cDNA sequence of human endothelial cell multimerin. A unique protein with RGDS, coiled-coil, and epidermal growth factor-like domains and a carboxyl terminus similar to the globular domain of complement C1q and collagens type VIII and X.

21 January 2018

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Identification of functionally important amino acid residues within the C2-domain of human factor V using alanine-scanning mutagenesis

21 January 2018

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Trp2063 and Trp2064 in the factor Va C2 domain are required for high-affinity binding to phospholipid membranes but not for assembly of the prothrombinase complex

21 January 2018

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The storage defects in grey platelet syndrome and alphadelta-storage pool deficiency affect alpha-granule factor V and multimerin storage without altering their proteolytic processing

21 January 2018

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Interaction between vitamin K-dependent protein S and the complement protein, C4b-binding protein. A link between coagulation and the complement system

21 January 2018

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Partial glycosylation at asparagine-2181 of the second C-type domain of human factor V modulates assembly of the prothrombinase complex.

21 January 2018

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Patients with congenital factor V deficiency have decreased factor Xa binding sites on their platelets

21 January 2018

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Fatal haemorrhage and incomplete block to embryogenesis in mice lacking coagulation factor V

21 January 2018

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Crystal structures of the membrane-binding C2 domain of human coagulation factor V

21 January 2018

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Interaction of factor VIII-von Willebrand Factor with phospholipid vesicles

21 January 2018

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Structure and function of the factor VIII gene and protein

21 January 2018

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Multimerin is found in the alpha-granules of resting platelets and is synthesized by a megakaryocytic cell line

21 January 2018

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Increasing the precision of comparative models with YASARA NOVA-a self-parameterizing force field

21 January 2018

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Cloning of a cDNA coding for human factor V, a blood coagulation factor homologous to factor VIII and ceruloplasmin

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M409866200

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15452129%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

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