HIV-1 causes CD4 cell death through DNA-dependent protein kinase during viral integration. (Q34348888)

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2 March 2020

title

HIV-1 causes CD4 cell death through DNA-dependent protein kinase during viral integration (English)

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2 March 2020

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4

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2 March 2020

6

Gary J Nabel

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2 March 2020

5

Richard A Koup

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2 March 2020

author name string

Arik Cooper

series ordinal

1

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2 March 2020

Mayra García

series ordinal

2

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2 March 2020

Constantinos Petrovas

series ordinal

3

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2 March 2020

language of work or name

English

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publication date

5 June 2013

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2 March 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23739328%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

volume

498

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2 March 2020

issue

7454

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2 March 2020

page(s)

376-379

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https://scigraph.springernature.com/pub.10.1038/nature12274

2 March 2020

exact match

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cites work

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DNA-Dependent protein kinase is not required for efficient lentivirus integration

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Wortmannin potentiates integrase-mediated killing of lymphocytes and reduces the efficiency of stable transduction by retroviruses.

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DNA damage sensors ATM, ATR, DNA-PKcs, and PARP-1 are dispensable for human immunodeficiency virus type 1 integration

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Essential role for DNA-PKcs in DNA double-strand break repair and apoptosis in ATM-deficient lymphocytes

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Cell cycle dependence of DNA-dependent protein kinase phosphorylation in response to DNA double strand breaks.

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Vpr cytopathicity independent of G2/M cell cycle arrest in human immunodeficiency virus type 1-infected CD4+ T cells

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Selective transmission of R5 HIV-1 over X4 HIV-1 at the dendritic cell-T cell infectious synapse is determined by the T cell activation state

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Human immunodeficiency virus type 1 spinoculation enhances infection through virus binding

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A novel DNA-dependent protein kinase inhibitor, NU7026, potentiates the cytotoxicity of topoisomerase II poisons used in the treatment of leukemia

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Identification of a highly potent and selective DNA-dependent protein kinase (DNA-PK) inhibitor (NU7441) by screening of chromenone libraries

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12 December 2020

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