Optimizing recombinant antibodies for intracellular function using hitchhiker-mediated survival selection (Q34313188)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25225416%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

title

Optimizing recombinant antibodies for intracellular function using hitchhiker-mediated survival selection (English)

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16 February 2020

4

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16 February 2020

author name string

Dujduan Waraho-Zhmayev

series ordinal

1

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16 February 2020

Bunyarit Meksiriporn

series ordinal

2

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16 February 2020

Alyse D Portnoff

series ordinal

3

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16 February 2020

publication date

14 September 2014

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Protein Engineering Design and Selection

16 February 2020

published in

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16 February 2020

volume

27

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16 February 2020

issue

10

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16 February 2020

page(s)

351-358

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A microbial sensor for discovering structural probes of protein misfolding and aggregation

16 February 2020

cites work

1 reference

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Twin-arginine translocase mutations that suppress folding quality control and permit export of misfolded substrate proteins

6 July 2018

1 reference

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The twin-arginine translocation (Tat) protein export pathway

6 July 2018

1 reference

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Engineering antibody fitness and function using membrane-anchored display of correctly folded proteins.

6 July 2018

1 reference

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Identifying and optimizing intracellular protein-protein interactions using bacterial genetic selection.

6 July 2018

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Genetic selection of solubility-enhanced proteins using the twin-arginine translocation system

6 July 2018

1 reference

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Development of GFP-based biosensors possessing the binding properties of antibodies

6 July 2018

1 reference

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Design and structural and thermodynamic studies of a chimeric protein derived from spectrin SH3-domain

6 July 2018

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Converging concepts of protein folding in vitro and in vivo

6 July 2018

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Versatile selection technology for intracellular protein-protein interactions mediated by a unique bacterial hitchhiker transport mechanism

6 July 2018

1 reference

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Discovery of amyloid-beta aggregation inhibitors using an engineered assay for intracellular protein folding and solubility

6 July 2018

1 reference

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Efficient isolation of soluble intracellular single-chain antibodies using the twin-arginine translocation machinery

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191445

Laboratory evolution of fast-folding green fluorescent protein using secretory pathway quality control

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191445

Adapting proteostasis for disease intervention

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191445

An scFv intrabody against the nonamyloid component of alpha-synuclein reduces intracellular aggregation and toxicity

6 July 2018

1 reference

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Functional Tat transport of unstructured, small, hydrophilic proteins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191445

Evidence for a dynamic and transient pathway through the TAT protein transport machinery

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191445

A scFv antibody mutant isolated in a genetic screen for improved export via the twin arginine transporter pathway exhibits faster folding

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191445

The bacterial twin-arginine translocation pathway

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191445

Intrabody-based approaches to cancer therapy: status and prospects

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191445

Genetic selection for protein solubility enabled by the folding quality control feature of the twin-arginine translocation pathway

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191445

Intrabody applications in neurological disorders: progress and future prospects

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191445

Cellular quality control screening to identify amino acid pairs for substituting the disulfide bonds in immunoglobulin fold domains.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191445

Folding quality control in the export of proteins by the bacterial twin-arginine translocation pathway

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191445

Direct in vivo screening of intrabody libraries constructed on a highly stable single-chain framework

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191445

Structural bases of stability-function tradeoffs in enzymes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191445

Evolution of an antibiotic resistance enzyme constrained by stability and activity trade-offs

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191445

Toward development of a screen to identify randomly encoded, foldable sequences.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191445

A cancer gene therapy approach utilizing an anti-erbB-2 single-chain antibody-encoding adenovirus (AD21): a phase I trial.

6 July 2018

1 reference

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Human anti-HIV-1 tat sFv intrabodies for gene therapy of advanced HIV-1-infection and AIDS.

6 July 2018

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The selection of intracellular antibodies.

6 July 2018

1 reference

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Secretion efficiency in Saccharomyces cerevisiae of bovine pancreatic trypsin inhibitor mutants lacking disulfide bonds is correlated with thermodynamic stability

6 July 2018

1 reference

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A pathway for targeting soluble misfolded proteins to the yeast vacuole

6 July 2018

1 reference

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Membrane targeting of a folded and cofactor-containing protein

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191445

Transport of cytochrome c derivatives by the bacterial Tat protein translocation system

28 October 2018

1 reference

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Directed evolution of a stable scaffold for T-cell receptor engineering.

28 October 2018

1 reference

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Yeast polypeptide fusion surface display levels predict thermal stability and soluble secretion efficiency

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191445

Protein folding stability can determine the efficiency of escape from endoplasmic reticulum quality control.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191445

Contribution of the intramolecular disulfide bridge to the folding stability of REIv, the variable domain of a human immunoglobulin kappa light chain.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191445

A natural antibody missing a cysteine in VH: consequences for thermodynamic stability and folding.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191445

The sec-independent twin-arginine translocation system can transport both tightly folded and malfolded proteins across the thylakoid membrane

28 October 2018

1 reference

12 December 2020

Co-translocation of a Periplasmic Enzyme Complex by a Hitchhiker Mechanism through the Bacterial Tat Pathway

1 reference

12 December 2020

Antigen recognition by conformational selection

1 reference

12 December 2020

Effect of active site residues in barnase on activity and stability

1 reference

12 December 2020

Identifiers

DOI

10.1093/PROTEIN/GZU038

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25225416%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25225416%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

1 reference

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