RhoA and cytoskeletal disruption mediate reduced osteoblastogenesis and enhanced adipogenesis of human mesenchymal stem cells in modeled microgravity (Q34312867)

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English	RhoA and cytoskeletal disruption mediate reduced osteoblastogenesis and enhanced adipogenesis of human mesenchymal stem cells in modeled microgravity	scientific article

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scholarly article

1 reference

Europe PubMed Central

1 August 2017

RhoA and cytoskeletal disruption mediate reduced osteoblastogenesis and enhanced adipogenesis of human mesenchymal stem cells in modeled microgravity (English)

1 reference

Europe PubMed Central

1 August 2017

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1 reference

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author name string

Valerie E Meyers

1

1 reference

Europe PubMed Central

1 August 2017

Majd Zayzafoon

2

1 reference

Europe PubMed Central

1 August 2017

Joanne T Douglas

3

1 reference

Europe PubMed Central

1 August 2017

Jay M McDonald

4

1 reference

Europe PubMed Central

1 August 2017

publication date

27 June 2005

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Europe PubMed Central

1 August 2017

Journal of Bone and Mineral Research

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Europe PubMed Central

1 August 2017

20

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Europe PubMed Central

1 August 2017

10

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Europe PubMed Central

1 August 2017

1858-1866

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Europe PubMed Central

1 August 2017

Regulation of bone morphogenetic protein-2 expression by endogenous prostaglandin E2 in human mesenchymal stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1351020

6 July 2018

Modulation of acto-myosin contractility in skeletal muscle myoblasts uncouples growth arrest from differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1351020

6 July 2018

Cortical and trabecular bone mineral loss from the spine and hip in long-duration spaceflight

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1351020

6 July 2018

Cell shape, cytoskeletal tension, and RhoA regulate stem cell lineage commitment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1351020

6 July 2018

Focal contacts organization in osteoblastic cells under microgravity and cyclic deformation conditions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1351020

6 July 2018

Endothelial stress by gravitational unloading: effects on cell growth and cytoskeletal organization.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1351020

6 July 2018

Physiological effects of microgravity on osteoblast morphology and cell biology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1351020

6 July 2018

Vascular smooth muscle cells orchestrate the assembly of type I collagen via alpha2beta1 integrin, RhoA, and fibronectin polymerization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1351020

6 July 2018

Use of a chimeric adenovirus vector enhances BMP2 production and bone formation

1 reference

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6 July 2018

Skeletal adaptations to alterations in weight-bearing activity: a comparison of models of disuse osteoporosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1351020

6 July 2018

Clinorotation-induced weightlessness influences the cytoskeleton of glial cells in culture

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1351020

6 July 2018

Spaceflight and clinorotation cause cytoskeleton and mitochondria changes and increases in apoptosis in cultured cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1351020

6 July 2018

Optimized suspension culture: the rotating-wall vessel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1351020

6 July 2018

Spaceflight effects on cultured embryonic chick bone cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1351020

6 July 2018

Effects of long-term microgravity exposure on cancellous and cortical weight-bearing bones of cosmonauts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1351020

6 July 2018

RAFTK/Pyk2 tyrosine kinase mediates the association of p190 RhoGAP with RasGAP and is involved in breast cancer cell invasion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1351020

6 July 2018

The response of bone to unloading

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1351020

6 July 2018

Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1351020

6 July 2018

Age-related osteogenic potential of mesenchymal stromal stem cells from human vertebral bone marrow

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1351020

6 July 2018

Integrin-mediated signals regulated by members of the rho family of GTPases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1351020

6 July 2018

Gene expression related to the differentiation of osteoblastic cells is altered by microgravity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1351020

6 July 2018

Bone formation and resorption biological markers in cosmonauts during and after a 180-day space flight (Euromir 95).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1351020

6 July 2018

The Rho family G proteins play a critical role in muscle differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1351020

6 July 2018

Rho GTPases and the actin cytoskeleton

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1351020

6 July 2018

Differentiation and transforming growth factor-beta receptor down-regulation by collagen-alpha2beta1 integrin interaction is mediated by focal adhesion kinase and its downstream signals in murine osteoblastic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1351020

6 July 2018

Evaluation of the concentration and bioactivity of adenovirus vectors for gene therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1351020

6 July 2018

Involvement of the small GTPase rho in integrin-mediated activation of mitogen-activated protein kinase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1351020

6 July 2018

An SH3 domain-containing GTPase-activating protein for Rho and Cdc42 associates with focal adhesion kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1351020

6 July 2018

Effects of microgravity on osteoblast growth activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1351020

6 July 2018

Modeled microgravity disrupts collagen I/integrin signaling during osteoblastic differentiation of human mesenchymal stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1351020

28 October 2018

Stretch of the vascular wall induces smooth muscle differentiation by promoting actin polymerization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1351020

28 October 2018

Regulation of osteoblast differentiation by Pasteurella multocida toxin (PMT): a role for Rho GTPase in bone formation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1351020

28 October 2018

Modeled microgravity inhibits osteogenic differentiation of human mesenchymal stem cells and increases adipogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1351020

28 October 2018

Aging is associated with decreased maximal life span and accelerated senescence of bone marrow stromal cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1351020

28 October 2018

Regulation of endothelial nitric oxide synthase by the actin cytoskeleton

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1351020

28 October 2018

Direct Interaction of Focal Adhesion Kinase with p190RhoGEF

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1351020

28 October 2018

The role of cytoskeleton in cell changes under condition of simulated microgravity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1351020

28 October 2018

Association of globular beta-actin with intracellular lipid droplets in rat adrenocortical cells and adipocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1351020

28 October 2018

Demonstration of cellular aging and senescence in serially passaged long-term cultures of human trabecular osteoblasts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1351020

28 October 2018

Signal transduction of mechanical stimuli is dependent on microfilament integrity: identification of osteopontin as a mechanically induced gene in osteoblasts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1351020

28 October 2018

Reduced shear stress: a major component in the ability of mammalian tissues to form three-dimensional assemblies in simulated microgravity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1351020

28 October 2018

Senescence-associated alterations of cytoskeleton: extraordinary production of vimentin that anchors cytoplasmic p53 in senescent human fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/16160744

12 December 2020

based on heuristic

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Age-related variations in the microstructure of human tibial cancellous bone

1 reference

https://pubmed.ncbi.nlm.nih.gov/16160744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of Rho GTPase Signaling Regulates a Switch between Adipogenesis and Myogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16160744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human osteoblasts from younger normal and osteoporotic donors show differences in proliferation and TGF beta-release in response to cyclic strain

1 reference

https://pubmed.ncbi.nlm.nih.gov/16160744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of 1- and 6-month spaceflight on bone mass and biochemistry in two humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/16160744

12 December 2020

based on heuristic

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Endocrine relationships during human spaceflight

1 reference

https://pubmed.ncbi.nlm.nih.gov/16160744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1359/JBMR.050611

1 reference

Europe PubMed Central

1 August 2017

1 reference

Europe PubMed Central

1 August 2017

1 reference

Europe PubMed Central

1 August 2017

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