Loss of Timp3 gene leads to abdominal aortic aneurysm formation in response to angiotensin II (Q34311153)

1 August 2017

Loss of Timp3 gene leads to abdominal aortic aneurysm formation in response to angiotensin II (English)

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abdominal aortic aneurysm

1 August 2017

1 reference

Ratnadeep Basu

1

1 reference

1 August 2017

Dong Fan

2

1 reference

1 August 2017

Vijay Kandalam

3

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1 August 2017

Jiwon Lee

4

1 reference

1 August 2017

Subhash K Das

5

1 reference

1 August 2017

Xiuhua Wang

6

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1 August 2017

Troy A Baldwin

7

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1 August 2017

Gavin Y Oudit

8

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1 August 2017

Zamaneh Kassiri

9

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1 August 2017

language of work or name

English

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publication date

9 November 2012

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Journal of Biological Chemistry

1 August 2017

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1 August 2017

287

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1 August 2017

53

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1 August 2017

44083-44096

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MMP-2 regulates Erk1/2 phosphorylation and aortic dilatation in Marfan syndrome

1 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531724

Transient exposure of neonatal female mice to testosterone abrogates the sexual dimorphism of abdominal aortic aneurysms

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531724

Proapoptotic protein Bim is differentially required during thymic clonal deletion to ubiquitous versus tissue-restricted antigens

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531724

Medical therapy of thoracic aortic aneurysms: are we there yet?

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531724

Tissue inhibitor of metalloproteinases (TIMPs) in heart failure

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531724

Current status of medical management for abdominal aortic aneurysm

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531724

Interleukin 6 knockout prevents angiotensin II hypertension: role of renal vasoconstriction and janus kinase 2/signal transducer and activator of transcription 3 activation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531724

Early activation of matrix metalloproteinases underlies the exacerbated systolic and diastolic dysfunction in mice lacking TIMP3 following myocardial infarction

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531724

Endovascular repair of aortic aneurysm in patients physically ineligible for open repair

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531724

Association of statin prescription with small abdominal aortic aneurysm progression

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531724

Abdominal aortic aneurysms, or a relatively large diameter of non-aneurysmal aortas, increase total and cardiovascular mortality: the Tromsø study

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531724

Simultaneous transforming growth factor beta-tumor necrosis factor activation and cross-talk cause aberrant remodeling response and myocardial fibrosis in Timp3-deficient heart

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531724

Vascular extracellular matrix and arterial mechanics

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531724

Loss of TIMP3 enhances interstitial nephritis and fibrosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531724

Clinical trial of doxycycline for matrix metalloproteinase-9 inhibition in patients with an abdominal aneurysm: doxycycline selectively depletes aortic wall neutrophils and cytotoxic T cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531724

Regional heterogeneity within the aorta: relevance to aneurysm disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531724

Angiotensin receptor blockers: novel role in high-risk patients

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531724

Inflammatory macrophage migration requires MMP-9 activation by plasminogen in mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531724

Macrophage roles following myocardial infarction

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531724

A randomized, placebo-controlled trial of doxycycline after endoluminal aneurysm repair

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531724

Medical management of small abdominal aortic aneurysms

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531724

Angiotensin receptor blockers versus angiotensin-converting enzyme inhibitors: where do we stand now?

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531724

Cyclic strain-mediated matrix metalloproteinase regulation within the vascular endothelium: a force to be reckoned with

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531724

Individual Timp deficiencies differentially impact pro-MMP-2 activation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531724

Genetic analysis of polymorphisms in biologically relevant candidate genes in patients with abdominal aortic aneurysms

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531724

Thoracic and abdominal aortic aneurysms

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531724

Matrix metalloproteinases 2 and 9 work in concert to produce aortic aneurysms

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531724

Use of doxycycline to decrease the growth rate of abdominal aortic aneurysms: a randomized, double-blind, placebo-controlled pilot study

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531724

TIMP-3 binds to sulfated glycosaminoglycans of the extracellular matrix

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531724

Targeted gene disruption of matrix metalloproteinase-9 (gelatinase B) suppresses development of experimental abdominal aortic aneurysms

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531724

Local overexpression of TIMP-1 prevents aortic aneurysm degeneration and rupture in a rat model

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531724

Tissue inhibitor of metalloproteinases-3 (TIMP-3) is an extracellular matrix-associated protein with a distinctive pattern of expression in mouse cells and tissues

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531724

Production and localization of 92-kilodalton gelatinase in abdominal aortic aneurysms. An elastolytic metalloproteinase expressed by aneurysm-infiltrating macrophages

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531724

Elastin degradation by mononuclear phagocytes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531724

Proteinases secreted by human mononuclear phagocytes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531724

Matrix metalloproteinase degradation of elastin, type IV collagen and proteoglycan. A quantitative comparison of the activities of 95 kDa and 72 kDa gelatinases, stromelysins-1 and -2 and punctuated metalloproteinase (PUMP).

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531724

Propranolol for small abdominal aortic aneurysms: results of a randomized trial

6 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.425652

Prevalence of and risk factors for abdominal aortic aneurysms in a population-based study : The Tromsø Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.425652

Transcriptional regulation of TIMPs in ascending aorta aneurysms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.425652

Unaltered secretion of beta-amyloid precursor protein in gelatinase A (matrix metalloproteinase 2)-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.425652

Differential effects of doxycycline, a broad-spectrum matrix metalloproteinase inhibitor, on angiotensin II-induced atherosclerosis and abdominal aortic aneurysms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.425652

Cyclophilin A enhances vascular oxidative stress and the development of angiotensin II-induced aortic aneurysms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.425652

TGF-beta activity protects against inflammatory aortic aneurysm progression and complications in angiotensin II-infused mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.425652

Rapid dilation of the abdominal aorta during infusion of angiotensin II detected by noninvasive high-frequency ultrasonography.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.425652

Differential expression of MMPs and TIMPs in moderate and severe heart failure in a transgenic model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.425652

Prevalence and associations of abdominal aortic aneurysm detected through screening. Aneurysm Detection and Management (ADAM) Veterans Affairs Cooperative Study Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.425652

Matrix metalloproteinase-2 is an interstitial collagenase. Inhibitor-free enzyme catalyzes the cleavage of collagen fibrils and soluble native type I collagen generating the specific 3/4- and 1/4-length fragments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.425652

Monocyte chemotactic activity in human abdominal aortic aneurysms: role of elastin degradation peptides and the 67-kD cell surface elastin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.425652

Tissue plasminogen activator (t-PA) promotes neutrophil degranulation and MMP-9 release.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.425652

Prolonged administration of doxycycline in patients with small asymptomatic abdominal aortic aneurysms: report of a prospective (Phase II) multicenter study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.425652

Combination of Tumor Necrosis Factor-α Ablation and Matrix Metalloproteinase Inhibition Prevents Heart Failure After Pressure Overload in Tissue Inhibitor of Metalloproteinase-3 Knock-Out Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.425652

Ubiquitous Elevation of Matrix Metalloproteinase-2 Expression in the Vasculature of Patients With Abdominal Aneurysms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.425652

Localization of matrix metalloproteinase 2 within the aneurysmal and normal aortic wall

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.425652

TIMP2 deficiency accelerates adverse post-myocardial infarction remodeling because of enhanced MT1-MMP activity despite lack of MMP2 activation

21 January 2018

1 reference

12 December 2020

Associations of plasma renin with 10-year cardiovascular mortality, sudden cardiac death, and death due to heart failure

1 reference

12 December 2020

Lack of tissue inhibitor of metalloproteinases 2 leads to exacerbated left ventricular dysfunction and adverse extracellular matrix remodeling in response to biomechanical stress

1 reference

12 December 2020

Role of matrix metalloproteinases in early hypertensive vascular remodeling

1 reference

12 December 2020

Effects of deletion of the tissue inhibitor of matrix metalloproteinases-1 gene on the progression of murine thoracic aortic aneurysms

1 reference

12 December 2020

Inflammation and matrix metalloproteinases in the enlarging abdominal aortic aneurysm

1 reference

12 December 2020

Evidence for altered balance between matrix metalloproteinases and their inhibitors in human aortic diseases

1 reference

12 December 2020

Matrix metalloproteinase-2 production and its binding to the matrix are increased in abdominal aortic aneurysms

1 reference

12 December 2020

Enhanced abdominal aortic aneurysm in TIMP-1-deficient mice

1 reference

12 December 2020

Thoracic aorta evaluation in patients with Takayasu's arteritis by transesophageal echocardiography

1 reference

12 December 2020

Expression of matrix metalloproteinases and endogenous inhibitors within ascending aortic aneurysms of patients with Marfan syndrome

1 reference

12 December 2020

Effects of tissue inhibitor of metalloproteinase 2 deficiency on aneurysm formation

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M112.425652

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1 August 2017

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1 August 2017

1 reference