Ypt and Rab GTPases: insight into functions through novel interactions (Q34309095)

1 August 2017

1 reference

title

Ypt and Rab GTPases: insight into functions through novel interactions (English)

1 reference

1 August 2017

N Segev

1

1 reference

1 August 2017

1 August 2001

1 reference

Current Opinion in Cell Biology

1 August 2017

1 reference

1 August 2017

13

1 reference

1 August 2017

500-511

1 reference

1 August 2017

4

1 reference

A ras-like protein is required for a post-Golgi event in yeast secretion

1 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

The yeast GTP-binding YPT1 protein and a mammalian counterpart are associated with the secretion machinery

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

The GTP-binding protein Ypt1 is required for transport in vitro: the Golgi apparatus is defective in ypt1 mutants

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

GTP-binding Ypt1 protein and Ca2+ function independently in a cell-free protein transport reaction

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

Vesicular transport: how many Ypt/Rab-GTPases make a eukaryotic cell?

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

Ypt/rab gtpases: regulators of protein trafficking

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

The mammalian Rab family of small GTPases: definition of family and subfamily sequence motifs suggests a mechanism for functional specificity in the Ras superfamily.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

Role of Rab GTPases in membrane traffic

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

Rab proteins as membrane organizers

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

Structural basis of activation and GTP hydrolysis in Rab proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

Crystal structures of a Rab protein in its inactive and active conformations

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

High-resolution crystal structure of S. cerevisiae Ypt51(DeltaC15)-GppNHp, a small GTP-binding protein involved in regulation of endocytosis

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

Molecular dissection of guanine nucleotide dissociation inhibitor function in vivo. Rab-independent binding to membranes and role of Rab recycling factors

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

A novel membrane-anchored Rab5 interacting protein required for homotypic endosome fusion

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

Sec2p mediates nucleotide exchange on Sec4p and is involved in polarized delivery of post-Golgi vesicles

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

TRAPP stimulates guanine nucleotide exchange on Ypt1p

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

The TRAPP complex is a nucleotide exchanger for Ypt1 and Ypt31/32.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

Vps9p is a guanine nucleotide exchange factor involved in vesicle-mediated vacuolar protein transport

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

Ric1p and Rgp1p form a complex that catalyses nucleotide exchange on Ypt6p

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

New component of the vacuolar class C-Vps complex couples nucleotide exchange on the Ypt7 GTPase to SNARE-dependent docking and fusion

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

Requirement of nucleotide exchange factor for Ypt1 GTPase mediated protein transport

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

TRAPP stably associates with the Golgi and is required for vesicle docking

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

Sec2 protein contains a coiled-coil domain essential for vesicular transport and a dispensable carboxy terminal domain

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

A Ypt/Rab effector complex containing the Sec1 homolog Vps33p is required for homotypic vacuole fusion

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

A novel Rab5 GDP/GTP exchange factor complexed to Rabaptin-5 links nucleotide exchange to effector recruitment and function

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

The Rab3 GDP/GTP exchange factor homolog AEX-3 has a dual function in synaptic transmission

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

Identification of regulators for Ypt1 GTPase nucleotide cycling

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

A yeast GTPase-activating protein that interacts specifically with a member of the Ypt/Rab family

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

Identification of a Sec4p GTPase-activating protein (GAP) as a novel member of a Rab GAP family

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

Two new members of a family of Ypt/Rab GTPase activating proteins. Promiscuity of substrate recognition

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

Msb4p, a protein involved in Cdc42p-dependent organization of the actin cytoskeleton, is a Ypt/Rab-specific GAP.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

Primary structure and biochemical characterization of yeast GTPase-activating proteins with substrate preference for the transport GTPase Ypt7p

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

Characterization of GAPCenA, a GTPase activating protein for Rab6, part of which associates with the centrosome

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

The tuberous sclerosis 2 gene product, tuberin, functions as a Rab5 GTPase activating protein (GAP) in modulating endocytosis

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

Crystal structure of the GAP domain of Gyp1p: first insights into interaction with Ypt/Rab proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

GTP hydrolysis is not important for Ypt1 GTPase function in vesicular transport

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

Identification of novel, evolutionarily conserved Cdc42p-interacting proteins and of redundant pathways linking Cdc24p and Cdc42p to actin polarization in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

The role of ARF and Rab GTPases in membrane transport

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

How do Rab proteins function in membrane traffic?

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

TRAPP, a highly conserved novel complex on the cis-Golgi that mediates vesicle docking and fusion

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

GTPase activity of Rab5 acts as a timer for endocytic membrane fusion

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

The Ypt1 GTPase is essential for the first two steps of the yeast secretory pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

VPS21 controls entry of endocytosed and biosynthetic proteins into the yeast prevacuolar compartment.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

Mediation of the attachment or fusion step in vesicular transport by the GTP-binding Ypt1 protein

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

Two new Ypt GTPases are required for exit from the yeast trans-Golgi compartment

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

A novel role for Rab5-GDI in ligand sequestration into clathrin-coated pits.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

Rab5 regulates motility of early endosomes on microtubules

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

Phosphatidylinositol-3-OH kinases are Rab5 effectors.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

Transport-vesicle targeting: tethers before SNAREs

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

The Rab5 effector EEA1 is a core component of endosome docking

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

Selective membrane recruitment of EEA1 suggests a role in directional transport of clathrin-coated vesicles to early endosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

Interaction of the EEA1 FYVE finger with phosphatidylinositol 3-phosphate and early endosomes. Role of conserved residues

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

Rabenosyn-5, a novel Rab5 effector, is complexed with hVPS45 and recruited to endosomes through a FYVE finger domain

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

The Rab5 effector EEA1 interacts directly with syntaxin-6

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

Oligomeric complexes link Rab5 effectors with NSF and drive membrane fusion via interactions between EEA1 and syntaxin 13

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

Direct interaction of EEA1 with Rab5b

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

The phosphatidylinositol 3-phosphate binding protein Vac1p interacts with a Rab GTPase and a Sec1p homologue to facilitate vesicle-mediated vacuolar protein sorting

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

Rabaptin-5 is a direct effector of the small GTPase Rab5 in endocytic membrane fusion

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

Role of Rab9 GTPase in facilitating receptor recruitment by TIP47

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

Physical and functional interaction of rabphilin-11 with mammalian Sec13 protein. Implication in vesicle trafficking

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

The Sar1 GTPase coordinates biosynthetic cargo selection with endoplasmic reticulum export site assembly

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

Rab1 recruitment of p115 into a cis-SNARE complex: programming budding COPII vesicles for fusion

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

Cruising along microtubule highways: how membranes move through the secretory pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

Interaction of a Golgi-associated kinesin-like protein with Rab6

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

Phosphatidylinositol(3)-phosphate signaling mediated by specific binding to RING FYVE domains

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

The role of the tethering proteins p115 and GM130 in transport through the Golgi apparatus in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

The p115-interactive proteins GM130 and giantin participate in endoplasmic reticulum-Golgi traffic

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

Vac1p coordinates Rab and phosphatidylinositol 3-kinase signaling in Vps45p-dependent vesicle docking/fusion at the endosome

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

EEA1 links PI(3)K function to Rab5 regulation of endosome fusion

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

The exocyst is an effector for Sec4p, targeting secretory vesicles to sites of exocytosis

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

The docking stage of yeast vacuole fusion requires the transfer of proteins from a cis-SNARE complex to a Rab/Ypt protein

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

Membrane fusion and exocytosis

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

Promiscuity in Rab-SNARE interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

Sec1/Munc18 proteins: mediators of membrane fusion moving to center stage

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

Structural basis of Rab effector specificity: crystal structure of the small G protein Rab3A complexed with the effector domain of rabphilin-3A

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

GTPase cascades choreographing cellular behavior: movement, morphogenesis, and more

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

Distinct Rab-binding domains mediate the interaction of Rabaptin-5 with GTP-bound Rab4 and Rab5

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

Involvement of Rabphilin3 in endocytosis through interaction with Rabaptin5.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

The stress-induced MAP kinase p38 regulates endocytic trafficking via the GDI:Rab5 complex

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

Epidermal growth factor and membrane trafficking. EGF receptor activation of endocytosis requires Rab5a

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

The Eps8 protein coordinates EGF receptor signalling through Rac and trafficking through Rab5

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

Gradient formation of the TGF-beta homolog Dpp.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

A genomic perspective on membrane compartment organization.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

Of yeast, mice, and men. Rab proteins and organelle transport

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

Rab27a regulates the peripheral distribution of melanosomes in melanocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

Rab1 interaction with a GM130 effector complex regulates COPII vesicle cis--Golgi tethering

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

The vesicle docking protein p115 binds GM130, a cis-Golgi matrix protein, in a mitotically regulated manner

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

Isolation and characterization of a GDP/GTP exchange protein specific for the Rab3 subfamily small G proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

Initial docking of ER-derived vesicles requires Uso1p and Ypt1p but is independent of SNARE proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900242-8

7 January 2021

10.1016/S0955-0674(00)00242-8

Identifiers

DOI

1 reference

1 August 2017

1 reference

PubMed ID

11454458