Monoclonal antibodies targeting the HR2 domain and the region immediately upstream of the HR2 of the S protein neutralize in vitro infection of severe acute respiratory syndrome coronavirus. (Q34301708)

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English	Monoclonal antibodies targeting the HR2 domain and the region immediately upstream of the HR2 of the S protein neutralize in vitro infection of severe acute respiratory syndrome coronavirus.	scientific article

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14 January 2020

Monoclonal antibodies targeting the HR2 domain and the region immediately upstream of the HR2 of the S protein neutralize in vitro infection of severe acute respiratory syndrome coronavirus (English)

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Burtram C Fielding

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Seng Gee Lim

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Chih-Fong Chou

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Kuo-Ming Lip

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Shuo Shen

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Xiaoming Yang

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Choong-Tat Keng

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Aihua Zhang

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Hsueh-Ling Janice Oh

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Zhi-Hong Li

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Le-Ann Hwang

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Timothy H P Tan

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Josef Mayrhofer

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Falko G Falkner

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14 January 2020

Jianlin Fu

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Wanjin Hong

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14 January 2020

Yee-Joo Tan

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1 January 2006

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14 January 2020

Journal of Virology

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941-950

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14 January 2020

Identification and characterization of the putative fusion peptide of the severe acute respiratory syndrome-associated coronavirus spike protein

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Amino acids 1055 to 1192 in the S2 region of severe acute respiratory syndrome coronavirus S protein induce neutralizing antibodies: implications for the development of vaccines and antiviral agents

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Anti-human immunodeficiency virus type 1 (HIV-1) antibodies 2F5 and 4E10 require surprisingly few crucial residues in the membrane-proximal external region of glycoprotein gp41 to neutralize HIV-1.

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Structure of a proteolytically resistant core from the severe acute respiratory syndrome coronavirus S2 fusion protein

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Suppression of SARS-CoV entry by peptides corresponding to heptad regions on spike glycoprotein

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Severe acute respiratory syndrome coronavirus (SARS-CoV) infection inhibition using spike protein heptad repeat-derived peptides.

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Characterization of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) spike glycoprotein-mediated viral entry

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Potent neutralization of severe acute respiratory syndrome (SARS) coronavirus by a human mAb to S1 protein that blocks receptor association

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A 193-amino acid fragment of the SARS coronavirus S protein efficiently binds angiotensin-converting enzyme 2

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The Coronavirus Spike Protein Is a Class I Virus Fusion Protein: Structural and Functional Characterization of the Fusion Core Complex

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Functional analysis of an epitope in the S2 subunit of the murine coronavirus spike protein: involvement in fusion activity

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Identification of spike protein residues of murine coronavirus responsible for receptor-binding activity by use of soluble receptor-resistant mutants.

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Peptides from conserved regions of paramyxovirus fusion (F) proteins are potent inhibitors of viral fusion

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The JHM strain of mouse hepatitis virus induces a spike protein-specific Db-restricted cytotoxic T cell response

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Mapping of linear antigenic sites on the S glycoprotein of a neurotropic murine coronavirus with synthetic peptides: a combination of nine prediction algorithms fails to identify relevant epitopes and peptide immunogenicity is drastically influenced

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Interaction between heptad repeat 1 and 2 regions in spike protein of SARS-associated coronavirus: implications for virus fusogenic mechanism and identification of fusion inhibitors

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Neutralization and fusion inhibition activities of monoclonal antibodies specific for the S1 subunit of the spike protein of neurovirulent murine coronavirus JHMV c1-2 variant

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12 December 2020

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Epitope mapping and biological function analysis of antibodies produced by immunization of mice with an inactivated Chinese isolate of severe acute respiratory syndrome-associated coronavirus (SARS-CoV)

1 reference

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12 December 2020

based on heuristic

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10.1128/JVI.80.2.941-950.2006

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14 January 2020

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14 January 2020

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14 January 2020

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