Metabolic activation of polycyclic aromatic hydrocarbons to carcinogens by cytochromes P450 1A1 and 1B1. (Q34289529)

1 August 2017

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title

Metabolic activation of polycyclic aromatic hydrocarbons to carcinogens by cytochromes P450 1A1 and 1B1. (English)

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polycyclic aromatic hydrocarbons

1 August 2017

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Tsutomu Shimada

1

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PubMed ID

14720319

1 August 2017

Yoshiaki Fujii-Kuriyama

series ordinal

2

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PubMed ID

14720319

1 August 2017

language of work or name

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1 January 2004

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1 August 2017

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1 August 2017

95

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1-6

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1 August 2017

1

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Oxidation of toxic and carcinogenic chemicals by human cytochrome P-450 enzymes

1 August 2017

1 reference

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Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects

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Mutagenic activation of 3-methoxy-4-aminoazobenzene by mouse renal cytochrome P450 CYP4B1: cloning and characterization of mouse CYP4B1.

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Differential expression of CYP1A1 and CYP1B1 in human breast epithelial cells and breast tumor cells

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Benzo[a]pyrene 7,8-dihydrodiol is more carcinogenic than benzo[a]pyrene in newborn mice

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Metabolic activation of dibenzo[a,l]pyrene by human cytochrome P450 1A1 and P450 1B1 expressed in V79 Chinese hamster cells.

21 January 2018

1 reference

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Stereoselectivity of cytochrome P-450 isozymes and epoxide hydrolase in the metabolism of polycyclic aromatic hydrocarbons

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Catalytic properties of polymorphic human cytochrome P450 1B1 variants.

21 January 2018

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Cytochrome P450 CYP1B1 determines susceptibility to 7, 12-dimethylbenz[a]anthracene-induced lymphomas

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Cytochrome P450 1B1 determines susceptibility to dibenzo[a,l]pyrene-induced tumor formation

21 January 2018

1 reference

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Characterization of the mouse Cyp1B1 gene. Identification of an enhancer region that directs aryl hydrocarbon receptor-mediated constitutive and induced expression

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1 reference

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Expression of CYP1B1 but not CYP1A1 by primary cultured human mammary stromal fibroblasts constitutively and in response to dioxin exposure: role of the Ah receptor

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Different response of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-sensitive genes in human breast cancer MCF-7 and MDA-MB 231 cells

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Benzo[a]pyrene carcinogenicity is lost in mice lacking the aryl hydrocarbon receptor

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Arylhydrocarbon receptor-dependent induction of liver and lung cytochromes P450 1A1, 1A2, and 1B1 by polycyclic aromatic hydrocarbons and polychlorinated biphenyls in genetically engineered C57BL/6J mice

21 January 2018

1 reference

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Tissue-specific induction of cytochromes P450 1A1 and 1B1 by polycyclic aromatic hydrocarbons and polychlorinated biphenyls in engineered C57BL/6J mice of arylhydrocarbon receptor gene

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Metabolism of benzo[a]pyrene to trans-7,8-dihydroxy-7, 8-dihydrobenzo[a]pyrene by recombinant human cytochrome P450 1B1 and purified liver epoxide hydrolase.

21 January 2018

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Benzo[a]pyrene-induced toxicity: paradoxical protection in Cyp1a1(-/-) knockout mice having increased hepatic BaP-DNA adduct levels

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Genetic epidemiology of environmental toxicity and cancer susceptibility: human allelic polymorphisms in drug-metabolizing enzyme genes, their functional importance, and nomenclature issues

21 January 2018

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Molecular cloning of monkey P450 1A1 cDNA and expression in yeast

21 January 2018

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Resveratrol is a selective human cytochrome P450 1A1 inhibitor

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Cancer chemopreventive activity of resveratrol, a natural product derived from grapes

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1 reference

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Selectivity of Polycyclic Inhibitors for Human Cytochrome P450s 1A1, 1A2, and 1B1

21 January 2018

1 reference

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10.1111/J.1349-7006.2004.TB03162.X

21 January 2018

Identifiers

DOI

1 reference

1 August 2017

1 reference

PubMed ID

14720319