Distinct pathways mediate axon degeneration during apoptosis and axon-specific pruning (Q34279699)

1 August 2017

Distinct pathways mediate axon degeneration during apoptosis and axon-specific pruning (English)

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1 August 2017

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Corey L Cusack

1

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1 August 2017

Vijay Swahari

2

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1 August 2017

W Hampton Henley

3

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1 August 2017

J Michael Ramsey

4

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1 August 2017

Mohanish Deshmukh

5

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1 August 2017

language of work or name

English

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publication date

1 January 2013

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1 August 2017

Nature Communications

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1 August 2017

4

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1 August 2017

1876

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https://scigraph.springernature.com/pub.10.1038/ncomms2910

1 August 2017

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cites work

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Apoptotic and non-apoptotic roles of caspases in neuronal physiology and pathophysiology

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Caspases in synaptic plasticity

6 July 2018

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Rescue from excitotoxicity and axonal degeneration accompanied by age-dependent behavioral and neuroanatomical alterations in caspase-6-deficient mice

6 July 2018

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Axon degeneration: Molecular mechanisms of a self-destruction pathway

6 July 2018

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6 July 2018

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Intranasal delivery of caspase-9 inhibitor reduces caspase-6-dependent axon/neuron loss and improves neurological function after stroke

6 July 2018

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Triggering of a novel intrinsic apoptosis pathway by the kinase inhibitor staurosporine: activation of caspase-9 in the absence of Apaf-1.

6 July 2018

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miR-29b is activated during neuronal maturation and targets BH3-only genes to restrict apoptosis

6 July 2018

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Amyloid precursor protein cleavage-dependent and -independent axonal degeneration programs share a common nicotinamide mononucleotide adenylyltransferase 1-sensitive pathway

6 July 2018

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Activation of specific apoptotic caspases with an engineered small-molecule-activated protease

6 July 2018

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Wallerian degeneration, wld(s), and nmnat

6 July 2018

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APP binds DR6 to trigger axon pruning and neuron death via distinct caspases

6 July 2018

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Chromatin modification of Apaf-1 restricts the apoptotic pathway in mature neurons

6 July 2018

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Mechanisms of axon degeneration: from development to disease

6 July 2018

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Axon pruning: an essential step underlying the developmental plasticity of neuronal connections

6 July 2018

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A microfluidic culture platform for CNS axonal injury, regeneration and transport

6 July 2018

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Growth and survival signals controlling sympathetic nervous system development

6 July 2018

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Axon retraction and degeneration in development and disease

6 July 2018

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Regulation of Wallerian degeneration and nerve growth factor withdrawal-induced pruning of axons of sympathetic neurons by the proteasome and the MEK/Erk pathway

6 July 2018

1 reference

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Active caspase-6 and caspase-6-cleaved tau in neuropil threads, neuritic plaques, and neurofibrillary tangles of Alzheimer's disease

6 July 2018

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Proteasome inhibition arrests neurite outgrowth and causes "dying-back" degeneration in primary culture

6 July 2018

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Death receptor-induced cell killing

6 July 2018

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Critical function of endogenous XIAP in regulating caspase activation during sympathetic neuronal apoptosis

6 July 2018

1 reference

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Involvement of the ubiquitin-proteasome system in the early stages of wallerian degeneration

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183061

Stereotyped Pruning of Long Hippocampal Axon Branches Triggered by Retraction Inducers of the Semaphorin Family

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183061

Caspases: keys in the ignition of cell death

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183061

Axonal self-destruction and neurodegeneration

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183061

Apoptosis in the nervous system

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183061

Analysis of the mechanism of loss of trophic factor dependence associated with neuronal maturation: a phenotype indistinguishable from Bax deletion.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183061

Adaptive survival or rat sympathetic neurons cultured without supporting cells or exogenous nerve growth factor.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183061

Axonal degeneration is regulated by the apoptotic machinery or a NAD+-sensitive pathway in insects and mammals

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183061

p75NTR-dependent, myelin-mediated axonal degeneration regulates neural connectivity in the adult brain

28 October 2018

1 reference

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Apaf-1-independent programmed cell death in mouse development.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183061

Local caspase activity directs engulfment of dendrites during pruning.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183061

Identification of E2/E3 ubiquitinating enzymes and caspase activity regulating Drosophila sensory neuron dendrite pruning

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183061

Application of proteasomal inhibitors to mouse sympathetic neurons activates the intrinsic apoptotic pathway

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183061

Proteasomal degradation of caspase-6 in 17beta-estradiol-treated neurons

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183061

Splitting the apoptosome.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183061

Differential expression of apoptotic protease-activating factor-1 and caspase-3 genes and susceptibility to apoptosis during brain development and after traumatic brain injury.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183061

Evidence that Wallerian degeneration and localized axon degeneration induced by local neurotrophin deprivation do not involve caspases

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23695670

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NCOMMS2910

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Dimensions Publication ID

1 August 2017

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1 August 2017

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