Vitamin E succinate and cancer treatment: a vitamin E prototype for selective antitumour activity (Q34276153)

1 August 2017

4 references

17 September 2019

2 October 2019

14 September 2020

11 October 2020

Vitamin E succinate and cancer treatment: a vitamin E prototype for selective antitumour activity (English)

1 reference

1 August 2017

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heterocyclic compound

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17 September 2019

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2 October 2019

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14 September 2020

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11 October 2020

1 reference

https://api.crossref.org/works/10.1038/SJ.BJC.6601360

31 March 2024

J Neuzil

1

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language of work or name

English

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publication date

1 November 2003

1 reference

full work available at URL

1 August 2017

17 November 2003

4 references

17 September 2019

2 October 2019

14 September 2020

11 October 2020

https://www.nature.com/articles/6601360.pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14612885

https://europepmc.org/articles/PMC2394445

31 March 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14612885

https://europepmc.org/articles/PMC2394445?pdf=render

31 March 2024

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14612885

http://www.nature.com/articles/6601360.pdf

31 March 2024

file format

Portable Document Format

1 reference

https://api.crossref.org/works/10.1038/SJ.BJC.6601360

http://www.nature.com/articles/6601360

31 March 2024

1 reference

https://api.crossref.org/works/10.1038/SJ.BJC.6601360

British Journal of Cancer

31 March 2024

published in

5 references

1 August 2017

17 September 2019

2 October 2019

14 September 2020

11 October 2020

89

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1 August 2017

10

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1 August 2017

1822-1826

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https://scigraph.springernature.com/pub.10.1038/sj.bjc.6601360

1 August 2017

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cites work

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Alpha-tocopheryl succinate, the most effective form of vitamin E for adjuvant cancer treatment: a review

6 July 2018

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Alpha-tocopheryl succinate sensitises a T lymphoma cell line to TRAIL-induced apoptosis by suppressing NF-kappaB activation.

6 July 2018

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Inhibition of angiogenesis and promotion of melanoma dormancy by vitamin E succinate

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Vitamin E inhibits CD95 ligand expression and protects T cells from activation-induced cell death

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6 July 2018

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Alpha-tocopheryl succinate epitomizes a compound with a shift in biological activity due to pro-vitamin-to-vitamin conversion

6 July 2018

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Alpha-tocopheryl succinate, an agent with in vivo anti-tumour activity, induces apoptosis by causing lysosomal instability

6 July 2018

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Vitamin E inhibits melanoma growth in mice

6 July 2018

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Activation of extracellular signal-regulated kinase and c-Jun-NH(2)-terminal kinase but not p38 mitogen-activated protein kinases is required for RRR-alpha-tocopheryl succinate-induced apoptosis of human breast cancer cells.

6 July 2018

1 reference

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In vivo inhibition by antioxidants of adriamycin-induced apoptosis in murine peritoneal macrophages

6 July 2018

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Inhibition of inflammatory endothelial responses by a pathway involving caspase activation and p65 cleavage.

6 July 2018

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Induction of cancer cell apoptosis by alpha-tocopheryl succinate: molecular pathways and structural requirements

6 July 2018

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Selective cancer cell killing by alpha-tocopheryl succinate

6 July 2018

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Increased atherosclerosis in hyperlipidemic mice deficient in alpha -tocopherol transfer protein and vitamin E

6 July 2018

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Lysosomal release of cathepsin D precedes relocation of cytochrome c and loss of mitochondrial transmembrane potential during apoptosis induced by oxidative stress

6 July 2018

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Selectivity of TRAIL-mediated apoptosis of cancer cells and synergy with drugs: the trail to non-toxic cancer therapeutics (review).

6 July 2018

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The pH partition theory predicts the accumulation and toxicity of doxorubicin in normal and low-pH-adapted cells

6 July 2018

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Oxidative stress causes relocation of the lysosomal enzyme cathepsin D with ensuing apoptosis in neonatal rat cardiomyocytes

6 July 2018

1 reference

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The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain

6 July 2018

1 reference

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c-Jun involvement in vitamin E succinate induced apoptosis of reticuloendotheliosis virus transformed avian lymphoid cells

6 July 2018

1 reference

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Vitamin E succinate inhibits proliferation of BT-20 human breast cancer cells: increased binding of cyclin A negatively regulates E2F transactivation activity.

6 July 2018

1 reference

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Alpha-Tocopherol and beta-carotene supplements and lung cancer incidence in the alpha-tocopherol, beta-carotene cancer prevention study: effects of base-line characteristics and study compliance

6 July 2018

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Absorption, lipoprotein transport, and regulation of plasma concentrations of vitamin E in humans.

6 July 2018

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The selective antiproliferative effects of alpha-tocopheryl hemisuccinate and cholesteryl hemisuccinate on murine leukemia cells result from the action of the intact compounds

6 July 2018

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Human plasma vitamin E kinetics demonstrate rapid recycling of plasma RRR-alpha-tocopherol

6 July 2018

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Growth inhibition and apoptosis of RL human B lymphoma cells by vitamin E succinate and retinoic acid: role for transforming growth factor beta.

6 July 2018

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Effects of tocopherol (vitamin E) acid succinate on morphological alterations and growth inhibition in melanoma cells in culture

6 July 2018

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Vitamin E succinate inhibits colon cancer liver metastases

6 July 2018

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https://api.crossref.org/works/10.1038%2FSJ.BJC.6601360

Enhanced antioxidant and cytoprotective abilities of vitamin E succinate is associated with a rapid uptake advantage in rat hepatocytes and mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJC.6601360

Potentiation of anti-cancer effect by intravenous administration of vesiculated alpha-tocopheryl hemisuccinate on mouse melanoma in vivo

21 January 2018

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Superoxide is responsible for apoptosis in rat vascular smooth muscle cells induced by alpha-tocopheryl hemisuccinate

21 January 2018

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Mitochondria play a central role in apoptosis induced by alpha-tocopheryl succinate, an agent with antineoplastic activity: comparison with receptor-mediated pro-apoptotic signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJC.6601360

Novel vitamin E analogue decreases syngeneic mouse mammary tumor burden and reduces lung metastasis

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394445

Vitamin E succinate is a potent novel antineoplastic agent with high selectivity and cooperativity with tumor necrosis factor-related apoptosis-inducing ligand (Apo2 ligand) in vivo

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394445

Coenzyme Q blocks biochemical but not receptor-mediated apoptosis by increasing mitochondrial antioxidant protection

28 October 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394445

28 October 2018

https://api.crossref.org/works/10.1038%2FSJ.BJC.6601360

7 January 2021

inferred from DOI database lookup

The cell transmembrane pH gradient in tumors enhances cytotoxicity of specific weak acid chemotherapeutics.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394445

Processing of vitamin A and E in the human gastrointestinal tract

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394445

Vitamin E succinate (VES) induces Fas sensitivity in human breast cancer cells: role for Mr 43,000 Fas in VES-triggered apoptosis.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394445

Inhibition of NF-kappa B DNA binding activity by alpha-tocopheryl succinate

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394445

Rel/NF-kappaB transcription factors protect against tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by up-regulating the TRAIL decoy receptor DcR1

28 October 2018

1 reference

12 December 2020

Vitamin E succinate induces Fas-mediated apoptosis in estrogen receptor-negative human breast cancer cells

1 reference

12 December 2020

alpha-Tocopheryl succinate inhibits monocytic cell adhesion to endothelial cells by suppressing NF-kappa B mobilization

1 reference

12 December 2020

Prostate Cancer and Supplementation With α-Tocopherol and β-Carotene: Incidence and Mortality in a Controlled Trial

1 reference

12 December 2020

α-Tocopheryl succinate-induced apoptosis in Jurkat T cells involves caspase-3 activation, and both lysosomal and mitochondrial destabilisation

1 reference

12 December 2020

Administration of the tris salt of alpha-tocopheryl hemisuccinate inactivates CYP2E1, enhances microsomal alpha-tocopherol levels and protects against carbon tetrachloride-induced hepatotoxicity

1 reference

12 December 2020

Effects of supplemental alpha-tocopherol and beta-carotene on colorectal cancer: results from a controlled trial (Finland)

1 reference

12 December 2020

Lipoprotein-associated alpha-tocopheryl-succinate inhibits cell growth and induces apoptosis in human MCF-7 and HBL-100 breast cancer cells

1 reference

12 December 2020

Vitamin E succinate promotes breast cancer tumor dormancy

1 reference

12 December 2020

Ammonia effect on calcium-activated chloride secretion in T84 intestinal epithelial monolayers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJC.6601360

7 January 2021

inferred from DOI database lookup

American Journal of Physiology

8

280

G95

P Borel

2001

1 reference

https://api.crossref.org/works/10.1038/SJ.BJC.6601360

31 March 2024

Identifiers

1 reference

Dimensions Publication ID

1 August 2017

0 references

1 reference

1 August 2017

1 reference