AEZS-108 : a targeted cytotoxic analog of LHRH for the treatment of cancers positive for LHRH receptors. (Q34274245)

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1 February 2020

title

AEZS-108 : a targeted cytotoxic analog of LHRH for the treatment of cancers positive for LHRH receptors (English)

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1 February 2020

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1

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1 February 2020

Andrew Schally

series ordinal

4

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1 February 2020

author name string

Guenter Emons

series ordinal

2

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1 February 2020

Jacek Pinski

series ordinal

3

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language of work or name

English

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publication date

1 June 2012

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Expert Opinion on Investigational Drugs

1 February 2020

published in

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volume

21

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issue

6

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1 February 2020

page(s)

891-899

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Drug Insight: clinical use of agonists and antagonists of luteinizing-hormone-releasing hormone.

1 February 2020

cites work

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Hypothalamic hormones and cancer

21 January 2018

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Chemotherapy targeted to cancers through tumoral hormone receptors

21 January 2018

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Stability of cytotoxic luteinizing hormone-releasing hormone conjugate (AN-152) containing doxorubicin 14-O-hemiglutarate in mouse and human serum in vitro: implications for the design of preclinical studies.

21 January 2018

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Cytotoxic analogs of luteinizing hormone-releasing hormone containing doxorubicin or 2-pyrrolinodoxorubicin, a derivative 500-1000 times more potent

21 January 2018

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Internalization of cytotoxic analog AN-152 of luteinizing hormone-releasing hormone induces apoptosis in human endometrial and ovarian cancer cell lines independent of multidrug resistance-1 (MDR-1) system

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543784.2012.685128

New approaches to treatment of various cancers based on cytotoxic analogs of LHRH, somatostatin and bombesin

21 January 2018

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Targeted therapy of breast and gynecological cancers with cytotoxic analogues of peptide hormones

21 January 2018

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Administration of a targeted cytotoxic analog of luteinizing hormone-releasing hormone inhibits growth of estrogen-independent MDA-MB-231 human breast cancers in nude mice.

21 January 2018

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Expression of receptors for luteinizing hormone-releasing hormone in human ovarian and endometrial cancers: frequency, autoregulation, and correlation with direct antiproliferative activity of luteinizing hormone-releasing hormone analogues

21 January 2018

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Effective treatment of experimental human endometrial cancers with targeted cytotoxic luteinizing hormone-releasing hormone analogues AN-152 and AN-207.

21 January 2018

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Expression of receptors for luteinizing hormone-releasing hormone (LH-RH) in prostate cancers following therapy with LH-RH agonists.

21 January 2018

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Therapy of ovarian cancers with targeted cytotoxic analogs of bombesin, somatostatin, and luteinizing hormone-releasing hormone and their combinations.

21 January 2018

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Dose escalation and pharmacokinetic study of AEZS-108 (AN-152), an LHRH agonist linked to doxorubicin, in women with LHRH receptor-positive tumors

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543784.2012.685128

Luteinizing hormone-releasing hormone receptor targeted agents for prostate cancer

21 January 2018

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Estimates of cancer incidence and mortality in Europe in 2008.

21 January 2018

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Triple negative tumours: a critical review

21 January 2018

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Trastuzumab emtansine in human epidermal growth factor receptor 2-positive breast cancer: a review

21 January 2018

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Characteristics and distribution of receptors for [D-TRP6]-luteinizing hormone-releasing hormone, somatostatin, epidermal growth factor, and sex steroids in 500 biopsy samples of human breast cancer

21 January 2018

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11 October 2022

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Luteinizing hormone-releasing hormone receptor-targeted chemotherapy using AN-152

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11 October 2022

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Use of analogs of peptide hormones conjugated to cytotoxic radicals for chemotherapy targeted to receptors on tumors.

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Presence of membrane binding sites for [D-TRP6]-luteinizing hormone-releasing hormone in experimental pancreatic cancer

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11 October 2022

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High incidence of receptors for luteinizing hormone-releasing hormone (LHRH) and LHRH receptor gene expression in human prostate cancers

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1517/13543784.2012.685128

Growth inhibition of human ovarian cancers by cytotoxic analogues of luteinizing hormone-releasing hormone

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1517/13543784.2012.685128

Cytotoxic analogs of luteinizing hormone-releasing hormone bind with high affinity to human breast cancers

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1517/13543784.2012.685128

Gonadotropin releasing hormone binding sites in human epithelial ovarian carcinomata

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1517/13543784.2012.685128

Antitumor effects of the cytotoxic luteinizing hormone-releasing hormone analog AN-152 on human endometrial and ovarian cancers xenografted into nude mice

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1517/13543784.2012.685128

Identifiers

DOI

10.1517/13543784.2012.685128

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22577891%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

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