Enhanced genetic instability and dasatinib sensitivity in mammary tumor cells lacking NEDD9 (Q34267936)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20940402%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

title

Enhanced genetic instability and dasatinib sensitivity in mammary tumor cells lacking NEDD9 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20940402%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

main subject

dasatinib monohydrate

1 reference

1 reference

4

1 reference

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15 February 2020

author name string

Mahendra K Singh

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20940402%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Eugene Izumchenko

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20940402%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Andres J Klein-Szanto

3

1 reference

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15 February 2020

Marina Wolfson

5

1 reference

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15 February 2020

Erica A Golemis

6

1 reference

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15 February 2020

language of work or name

English

0 references

publication date

12 October 2010

1 reference

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15 February 2020

1 reference

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15 February 2020

volume

70

1 reference

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15 February 2020

page(s)

8907-8916

1 reference

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15 February 2020

issue

21

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describes a project that uses

15 February 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2970659/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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NEDD9 promotes oncogenic signaling in mammary tumor development.

6 July 2018

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Nedd9/Hef1/Cas-L mediates the effects of environmental pollutants on cell migration and plasticity

6 July 2018

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A new central scaffold for metastasis: parsing HEF1/Cas-L/NEDD9

6 July 2018

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6 July 2018

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HEF1-dependent Aurora A activation induces disassembly of the primary cilium

6 July 2018

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In vitro and in vivo synergy of MCP compounds with mitogen-activated protein kinase pathway- and microtubule-targeting inhibitors

6 July 2018

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Identification of candidate molecular markers predicting sensitivity in solid tumors to dasatinib: rationale for patient selection

6 July 2018

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Dasatinib, an orally active small molecule inhibitor of both the src and abl kinases, selectively inhibits growth of basal-type/"triple-negative" breast cancer cell lines growing in vitro

6 July 2018

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HEF1-aurora A interactions: points of dialog between the cell cycle and cell attachment signaling networks

6 July 2018

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Deregulation of HEF1 impairs M-phase progression by disrupting the RhoA activation cycle

6 July 2018

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HEF1 is a necessary and specific downstream effector of FAK that promotes the migration of glioblastoma cells

6 July 2018

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The focal adhesion scaffolding protein HEF1 regulates activation of the Aurora-A and Nek2 kinases at the centrosome

6 July 2018

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6 July 2018

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Stroma-derived three-dimensional matrices are necessary and sufficient to promote desmoplastic differentiation of normal fibroblasts

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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A novel ability of Smad3 to regulate proteasomal degradation of a Cas family member HEF1

6 July 2018

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Discovery of N-(2-chloro-6-methyl- phenyl)-2-(6-(4-(2-hydroxyethyl)- piperazin-1-yl)-2-methylpyrimidin-4- ylamino)thiazole-5-carboxamide (BMS-354825), a dual Src/Abl kinase inhibitor with potent antitumor activity in preclinical assays.

6 July 2018

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Comparative Oncogenomics Identifies NEDD9 as a Melanoma Metastasis Gene

28 October 2018

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10.1158/0008-5472.CAN-10-0353

28 October 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20940402%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20940402%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

1 reference