Targeted overexpression of osteoactivin in cells of osteoclastic lineage promotes osteoclastic resorption and bone loss in mice (Q34247178)

31 July 2017

Targeted overexpression of osteoactivin in cells of osteoclastic lineage promotes osteoclastic resorption and bone loss in mice (English)

1 reference

31 July 2017

1 reference

Matilda H-C Sheng

1

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31 July 2017

Jon E Wergedal

2

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31 July 2017

Subburaman Mohan

3

1 reference

31 July 2017

Mehran Amoui

4

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31 July 2017

David J Baylink

5

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31 July 2017

K-H William Lau

6

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31 July 2017

language of work or name

English

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publication date

20 April 2012

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31 July 2017

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31 July 2017

7

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31 July 2017

4

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31 July 2017

e35280

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Creative Commons CC0 License

31 July 2017

start time

20 April 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted, dedicated to the public domain by copyright holder

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cites work

ADAM10 releases a soluble form of the GPNMB/Osteoactivin extracellular domain with angiogenic properties

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Integrins, growth factors, and the osteoclast cytoskeleton

6 July 2018

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GPNMB expression in uveal melanoma: a potential for targeted therapy.

6 July 2018

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Upregulation of monocyte/macrophage HGFIN (Gpnmb/Osteoactivin) expression in end-stage renal disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335057

Targeted transgenic expression of an osteoclastic transmembrane protein-tyrosine phosphatase in cells of osteoclastic lineage increases bone resorption and bone loss in male young adult mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335057

Osteoactivin, an anabolic factor that regulates osteoblast differentiation and function

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335057

Osteoactivin is a novel osteoclastic protein and plays a key role in osteoclast differentiation and activity

6 July 2018

1 reference

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Microphthalmia transcription factor regulates the expression of the novel osteoclast factor GPNMB.

6 July 2018

1 reference

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Osteoactivin fragments produced by ectodomain shedding induce MMP-3 expression via ERK pathway in mouse NIH-3T3 fibroblasts

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335057

Novel osteoclast signaling mechanisms.

6 July 2018

1 reference

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Gpnmb is induced in macrophages by IFN-gamma and lipopolysaccharide and acts as a feedback regulator of proinflammatory responses

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335057

DC-HIL is a negative regulator of T lymphocyte activation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335057

IFN-gamma stimulates osteoclast formation and bone loss in vivo via antigen-driven T cell activation

6 July 2018

1 reference

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Osteoactivin acts as downstream mediator of BMP-2 effects on osteoblast function

6 July 2018

1 reference

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Glycoprotein nonmetastatic melanoma protein B, a potential molecular therapeutic target in patients with glioblastoma multiforme

6 July 2018

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CR011, a fully human monoclonal antibody-auristatin E conjugate, for the treatment of melanoma

6 July 2018

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The role(s) of Src kinase and Cbl proteins in the regulation of osteoclast differentiation and function

6 July 2018

1 reference

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Osteoactivin upregulates expression of MMP-3 and MMP-9 in fibroblasts infiltrated into denervated skeletal muscle in mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335057

Shedding light on ADAM metalloproteinases

6 July 2018

1 reference

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Expression of osteoactivin in rat and human liver and isolated rat liver cells

6 July 2018

1 reference

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Structure and regulation of Src family kinases

6 July 2018

1 reference

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Anti-osteoactivin antibody inhibits osteoblast differentiation and function in vitro

6 July 2018

1 reference

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Identification and characterization of the genes encoding human and mouse osteoactivin

6 July 2018

1 reference

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Multiple tissue-specific promoters control expression of the murine tartrate-resistant acid phosphatase gene

6 July 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335057

6 July 2018

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0035280

mRNA expression of the murine glycoprotein (transmembrane) nmb (Gpnmb) gene is linked to the developing retinal pigment epithelium and iris

21 January 2018

1 reference

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Hematopoietic growth factor inducible neurokinin-1 type: a transmembrane protein that is similar to neurokinin 1 interacts with substance P

6 July 2018

1 reference

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Cloning and characterization of osteoactivin, a novel cDNA expressed in osteoblasts

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335057

Mutations in genes encoding melanosomal proteins cause pigmentary glaucoma in DBA/2J mice

6 July 2018

1 reference

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Molecular cloning of a dendritic cell-associated transmembrane protein, DC-HIL, that promotes RGD-dependent adhesion of endothelial cells through recognition of heparan sulfate proteoglycans

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335057

Stimulatory effect of bone morphogenetic protein-2 on osteoclast-like cell formation and bone-resorbing activity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335057

The immune inhibitory receptor osteoactivin is upregulated in monocyte-derived dendritic cells by BCR-ABL tyrosine kinase inhibitors.

6 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0035280

Genome-wide expression profiling reveals new candidate genes associated with osteoarthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0035280

Osteoactivin expressed during cirrhosis development in rats fed a choline-deficient, l-amino acid-defined diet, accelerates motility of hepatoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0035280

Homeodomain transcription factors regulate BMP-2-induced osteoactivin transcription in osteoblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0035280

Analysis of distinct tartrate-resistant acid phosphatase promoter regions in transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0035280

In vivo and in vitro evidence that the high osteoblastic activity in C3H/HeJ mice compared to C57BL/6J mice is intrinsic to bone cells

21 January 2018

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12 December 2020

1 reference

12 December 2020

Transgenic expression of osteoactivin in the liver attenuates hepatic fibrosis in rats

1 reference

12 December 2020

Overexpression of osteoactivin protects skeletal muscle from severe degeneration caused by long-term denervation in mice

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0035280

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DOI

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31 July 2017

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31 July 2017

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