Parkinson's disease DJ-1 L166P alters rRNA biogenesis by exclusion of TTRAP from the nucleolus and sequestration into cytoplasmic aggregates via TRAF6 (Q34245014)

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English	Parkinson's disease DJ-1 L166P alters rRNA biogenesis by exclusion of TTRAP from the nucleolus and sequestration into cytoplasmic aggregates via TRAF6	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

31 July 2017

Parkinson's disease DJ-1 L166P alters rRNA biogenesis by exclusion of TTRAP from the nucleolus and sequestration into cytoplasmic aggregates via TRAF6 (English)

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Europe PubMed Central

PubMed publication ID

31 July 2017

Parkinson's disease

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Milena Pinto

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Stefano Gustincich

7

object named as

Stefano Gustincich

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Europe PubMed Central

PubMed publication ID

31 July 2017

author name string

Sandra Vilotti

1

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Europe PubMed Central

PubMed publication ID

31 July 2017

Marta Codrich

2

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Europe PubMed Central

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31 July 2017

Marco Dal Ferro

3

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Europe PubMed Central

PubMed publication ID

31 July 2017

Isidro Ferrer

5

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31 July 2017

Licio Collavin

6

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31 July 2017

Silvia Zucchelli

8

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31 July 2017

language of work or name

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publication date

20 April 2012

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Europe PubMed Central

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31 July 2017

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Europe PubMed Central

PubMed publication ID

31 July 2017

7

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Europe PubMed Central

PubMed publication ID

31 July 2017

4

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Europe PubMed Central

PubMed publication ID

31 July 2017

e35051

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Europe PubMed Central

PubMed publication ID

31 July 2017

copyright license

Creative Commons Attribution 4.0 International

20 April 2012

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April 2022 Public Data File from Crossref

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describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3332112/fullTextXML

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The PML nuclear bodies-associated protein TTRAP regulates ribosome biogenesis in nucleolar cavities upon proteasome inhibition.

1 reference

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6 July 2018

Tumor necrosis factor receptor-associated factor 6 (TRAF6) associates with huntingtin protein and promotes its atypical ubiquitination to enhance aggregate formation.

1 reference

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6 July 2018

Proteasome inhibitors induce nucleolar aggregation of proteasome target proteins and polyadenylated RNA by altering ubiquitin availability

1 reference

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6 July 2018

Interaction of noncoding RNA with the rDNA promoter mediates recruitment of DNMT3b and silencing of rRNA genes

1 reference

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DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy

1 reference

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DJ-1 is critical for mitochondrial function and rescues PINK1 loss of function

1 reference

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Parkinson disease-associated DJ-1 is required for the expression of the glial cell line-derived neurotrophic factor receptor RET in human neuroblastoma cells.

1 reference

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p53 localizes to intranucleolar regions distinct from the ribosome production compartments.

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Aggresome-forming TTRAP mediates pro-apoptotic properties of Parkinson's disease-associated DJ-1 missense mutations.

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Epigenetic control of rDNA loci in response to intracellular energy status

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Parkin-mediated K63-linked polyubiquitination targets misfolded DJ-1 to aggresomes via binding to HDAC6

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DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidase

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On the oligomeric state of DJ-1 protein and its mutants associated with Parkinson Disease. A combined computational and in vitro study.

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Potential roles for ubiquitin and the proteasome during ribosome biogenesis

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Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) and oxidative stress.

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Ubiquitin-proteasome system and Parkinson's diseases

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Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism

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Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain

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12 December 2020

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10.1371/JOURNAL.PONE.0035051

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Europe PubMed Central

PubMed publication ID

31 July 2017

2012PLoSO...735051V

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Europe PubMed Central

PubMed publication ID

31 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

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