A phase 1 study of ACE-536, a regulator of erythroid differentiation, in healthy volunteers (Q34235483)

31 July 2017

A phase 1 study of ACE-536, a regulator of erythroid differentiation, in healthy volunteers (English)

1 reference

31 July 2017

Kenneth M Attie

1

1 reference

31 July 2017

Mark J Allison

2

1 reference

31 July 2017

Ty McClure

3

1 reference

31 July 2017

Ingrid E Boyd

4

1 reference

31 July 2017

Dawn M Wilson

5

1 reference

31 July 2017

Amelia E Pearsall

6

1 reference

31 July 2017

Matthew L Sherman

7

1 reference

31 July 2017

26 April 2014

1 reference

American Journal of Hematology

31 July 2017

1 reference

31 July 2017

89

1 reference

31 July 2017

7

1 reference

31 July 2017

766-770

1 reference

Transforming growth factor-β superfamily ligand trap ACE-536 corrects anemia by promoting late-stage erythropoiesis

31 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4173124

An activin receptor IIA ligand trap corrects ineffective erythropoiesis in β-thalassemia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4173124

Clinical pharmacokinetics and pharmacodynamics of erythropoiesis-stimulating agents

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4173124

Hepcidin levels and their determinants in different types of myelodysplastic syndromes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4173124

β-thalassemia: a model for elucidating the dynamic regulation of ineffective erythropoiesis and iron metabolism

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4173124

Characterization of the ligand binding functionality of the extracellular domain of activin receptor type IIb.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4173124

Complex and context dependent regulation of hematopoiesis by TGF-beta superfamily signaling

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4173124

Inhibition of the TGF-beta receptor I kinase promotes hematopoiesis in MDS.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4173124

Ineffective erythropoiesis in beta-thalassemia is characterized by increased iron absorption mediated by down-regulation of hepcidin and up-regulation of ferroportin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4173124

Activin type IIA and IIB receptors mediate Gdf11 signaling in axial vertebral patterning

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4173124

Regulation of anterior/posterior patterning of the axial skeleton by growth/differentiation factor 11

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4173124

Stromal cell-mediated inhibition of erythropoiesis can be attenuated by Sotatercept (ACE-011), an activin receptor type II ligand trap.

6 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1002%2FAJH.23732

Single-dose, randomized, double-blind, placebo-controlled study of ACE-011 (ActRIIA-IgG1) in postmenopausal women

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1002%2FAJH.23732

Multiple-dose, safety, pharmacokinetic, and pharmacodynamic study of sotatercept (ActRIIA-IgG1), a novel erythropoietic agent, in healthy postmenopausal women

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4173124

28 October 2018

Identifiers

DOI

10.1002/AJH.23732

1 reference

31 July 2017

1 reference

31 July 2017

1 reference