High-content analysis of cancer-cell-specific apoptosis and inhibition of in vivo angiogenesis by synthetic (-)-pironetin and analogs. (Q34235175)

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5 February 2020

title

High-content analysis of cancer-cell-specific apoptosis and inhibition of in vivo angiogenesis by synthetic (-)-pironetin and analogs (English)

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5 February 2020

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5

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5 February 2020

Michael Tsang

8

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5 February 2020

Michael Tsang

9

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5 February 2020

author name string

Andreas Vogt

1

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5 February 2020

Peter A McPherson

2

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5 February 2020

Xiaoqiang Shen

3

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5 February 2020

Raghavan Balachandran

4

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5 February 2020

Brianne S Raccor

6

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5 February 2020

Scott G Nelson

7

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5 February 2020

Billy W Day

10

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5 February 2020

publication date

18 August 2009

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Chemical Biology and Drug Design

5 February 2020

published in

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volume

74

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issue

4

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page(s)

358-368

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Automated image-based phenotypic analysis in zebrafish embryos

5 February 2020

cites work

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6 July 2018

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Angiogenesis: an organizing principle for drug discovery?

6 July 2018

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Targeting multidrug resistance in cancer

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Cellular analysis of disorazole C and structure-activity relationship of analogs of the natural product

6 July 2018

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The anticancer natural product pironetin selectively targets Lys352 of alpha-tubulin.

6 July 2018

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A scalable high-content cytotoxicity assay insensitive to changes in mitochondrial metabolic activity

6 July 2018

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Microtubules as a target for anticancer drugs

6 July 2018

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Thiol-modifying phenylarsine oxide inhibits guanine nucleotide binding of Rho but not of Rac GTPases

6 July 2018

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Antimitotic peptides and depsipeptides

6 July 2018

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Clinical translation of angiogenesis inhibitors

6 July 2018

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Arteries and veins: making a difference with zebrafish

6 July 2018

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In vivo imaging of embryonic vascular development using transgenic zebrafish

6 July 2018

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Drug-like properties and the causes of poor solubility and poor permeability

6 July 2018

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The vascular anatomy of the developing zebrafish: an atlas of embryonic and early larval development

6 July 2018

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Synthesis of pironetin and related analogs: studies on structure-activity relationships as tubulin assembly inhibitors

6 July 2018

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Apoptosis induction via microtubule disassembly by an antitumour compound, pironetin.

6 July 2018

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Desoxyepothilone B is curative against human tumor xenografts that are refractory to paclitaxel.

6 July 2018

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Stages of embryonic development of the zebrafish

6 July 2018

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DNA crosslinking and cytotoxicity in normal and transformed human cells treated with antitumor nitrosoureas

6 July 2018

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Measurement of protein using bicinchoninic acid

6 July 2018

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Characterization of a new human diploid cell strain, IMR-90.

6 July 2018

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Antiproliferating activity of the mitotic inhibitor pironetin against vindesine- and paclitaxel-resistant human small cell lung cancer H69 cells.

6 July 2018

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Dolastatin 15 binds in the vinca domain of tubulin as demonstrated by Hummel-Dreyer chromatography

28 October 2018

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Epidermal growth factor receptor tyrosine kinase inhibition augments a murine model of pulmonary fibrosis.

28 October 2018

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High-content profiling of drug-drug interactions: cellular targets involved in the modulation of microtubule drug action by the antifungal ketoconazole

28 October 2018

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Pironetin, a novel plant growth regulator produced by Streptomyces sp. NK10958. I. Taxonomy, production, isolation and preliminary characterization.

28 October 2018

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Alteration of plasma membrane glycopeptides and gangliosides of Chinese hamster cells accompanying development of resistance to daunorubicin and vincristine

28 October 2018

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Antiangiogenesis is produced by nontoxic doses of vinblastine

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12 December 2020

Total synthesis of the immunosupressant (-)-pironetin (PA48153C)

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12 December 2020

Total synthesis of (-)-pironetin

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12 December 2020

Rapid analysis of angiogenesis drugs in a live fluorescent zebrafish assay

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12 December 2020

Cell cycle arrest and antitumor activity of pironetin and its derivatives

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12 December 2020

The microtubule-affecting drug paclitaxel has antiangiogenic activity

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12 December 2020

Catalytic asymmetric assembly of stereodefined propionate units: an enantioselective total synthesis of (-)-pironetin

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12 December 2020

10.1111/J.1747-0285.2009.00866.X

Identifiers

DOI

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5 February 2020

1 reference

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5 February 2020

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