Mapping of chromosome 1p deletions in myeloma identifies FAM46C at 1p12 and CDKN2C at 1p32.3 as being genes in regions associated with adverse survival. (Q34223730)

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English	Mapping of chromosome 1p deletions in myeloma identifies FAM46C at 1p12 and CDKN2C at 1p32.3 as being genes in regions associated with adverse survival.	scientific article

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14 February 2020

Mapping of chromosome 1p deletions in myeloma identifies FAM46C at 1p12 and CDKN2C at 1p32.3 as being genes in regions associated with adverse survival (English)

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14 February 2020

Brian A. Walker

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Gian Paolo Dagrada

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14 February 2020

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Christopher P Wardell

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Gareth J Morgan

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Fiona M Ross

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William J Tapper

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Laura Chiecchio

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Zoe J Konn

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Walter M Gregory

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Graham H Jackson

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J Anthony Child

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Faith E Davies

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14 February 2020

NCRI Haematology Oncology Studies Group

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12 October 2011

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Clinical Cancer Research

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7776-7784

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14 February 2020

A novel prognostic model in myeloma based on co-segregating adverse FISH lesions and the ISS: analysis of patients treated in the MRC Myeloma IX trial.

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Cyclophosphamide, thalidomide, and dexamethasone (CTD) as initial therapy for patients with multiple myeloma unsuitable for autologous transplantation.

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Initial genome sequencing and analysis of multiple myeloma

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First-line treatment with zoledronic acid as compared with clodronic acid in multiple myeloma (MRC Myeloma IX): a randomised controlled trial

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The t(14;20) is a poor prognostic factor in myeloma but is associated with long-term stable disease in monoclonal gammopathies of undetermined significance

1 reference

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5 July 2018

Correlation between array-comparative genomic hybridization-defined genomic gains and losses and survival: identification of 1p31-32 deletion as a prognostic factor in myeloma

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5 July 2018

Homozygous deletion mapping in myeloma samples identifies genes and an expression signature relevant to pathogenesis and outcome

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5 July 2018

Timing of acquisition of deletion 13 in plasma cell dyscrasias is dependent on genetic context

1 reference

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5 July 2018

International Myeloma Working Group molecular classification of multiple myeloma: spotlight review.

1 reference

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5 July 2018

Deletions of CDKN2C in multiple myeloma: biological and clinical implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5751883

5 July 2018

Paradoxical expression of INK4c in proliferative multiple myeloma tumors: bi-allelic deletion vs increased expression

1 reference

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5 July 2018

Frequent gain of chromosome band 1q21 in plasma-cell dyscrasias detected by fluorescence in situ hybridization: incidence increases from MGUS to relapsed myeloma and is related to prognosis and disease progression following tandem stem-cell transpla

1 reference

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5 July 2018

Molecular pathogenesis and a consequent classification of multiple myeloma

1 reference

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5 July 2018

Genetic abnormalities and survival in multiple myeloma: the experience of the Intergroupe Francophone du Myélome.

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28 October 2018

Clinical and biologic implications of recurrent genomic aberrations in myeloma

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28 October 2018

Gene mapping and expression analysis of 16q loss of heterozygosity identifies WWOX and CYLD as being important in determining clinical outcome in multiple myeloma

1 reference

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Deletion of the short arm of chromosome 1 (del 1p) is a strong predictor of poor outcome in myeloma patients undergoing an autotransplant

1 reference

https://pubmed.ncbi.nlm.nih.gov/21994415

12 December 2020

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The clinical impact and molecular biology of del(17p) in multiple myeloma treated with conventional or thalidomide-based therapy

1 reference

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A compendium of myeloma-associated chromosomal copy number abnormalities and their prognostic value

1 reference

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12 December 2020

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inferred from PubMed ID database lookup

Integration of global SNP-based mapping and expression arrays reveals key regions, mechanisms, and genes important in the pathogenesis of multiple myeloma

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deletion of chromosome 13 detected by conventional cytogenetics is a critical prognostic factor in myeloma

1 reference

https://pubmed.ncbi.nlm.nih.gov/21994415

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aberrant global methylation patterns affect the molecular pathogenesis and prognosis of multiple myeloma

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormalities of chromosome 1p/q are highly associated with chromosome 13/13q deletions and are an adverse prognostic factor for the outcome of high-dose chemotherapy in patients with multiple myeloma

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1158/1078-0432.CCR-11-1791

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14 February 2020

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14 February 2020

1 reference

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14 February 2020

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