Immunomodulatory effects of therapeutic gold compounds. Gold sodium thiomalate inhibits the activity of T cell protein kinase C (Q34220395)

31 July 2017

Immunomodulatory effects of therapeutic gold compounds. Gold sodium thiomalate inhibits the activity of T cell protein kinase C (English)

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17 September 2022

author name string

K. Hashimoto

1

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17 September 2022

C. E. Whitehurst

2

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17 September 2022

T. Matsubara

3

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17 September 2022

K. Hirohata

4

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17 September 2022

P. E. Lipsky

5

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17 September 2022

language of work or name

English

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publication date

1 June 1992

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full work available at URL

31 July 2017

https://europepmc.org/articles/PMC295882

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https://europepmc.org/articles/PMC295882?pdf=render

17 September 2022

file format

Portable Document Format

online access status

open access

content deliverer

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Journal of Clinical Investigation

17 September 2022

published in

1 reference

31 July 2017

89

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31 July 2017

6

1 reference

31 July 2017

1839-1848

1 reference

Immunopharmacology of gold.

31 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295882

Phenotype of the accessory cell necessary for mitogen-stimulated T and B cell responses in human peripheral blood: delineation by its sensitivity to the lysosomotropic agent, L-leucine methyl ester

5 July 2018

1 reference

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Treatment of intractable rheumatoid arthritis with total lymphoid irradiation

5 July 2018

1 reference

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Immune interferon in serum and synovial fluid in rheumatoid arthritis and related disorders

5 July 2018

1 reference

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Two distinct Ca2+ proteases (calpain I and calpain II) purified concurrently by the same method from rat kidney

5 July 2018

1 reference

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Gold metabolism in patients with rheumatoid arthritis treated with gold compounds—reinvestigated

5 July 2018

1 reference

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Clinical response and serum gold levels in chrysotherapy. Lack of correlation

5 July 2018

1 reference

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The formation of stable E rosettes after neuraminidase treatment of either human peripheral blood lymphocytes or of sheep red blood cells

5 July 2018

1 reference

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A modified procedure for fractionating histones

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1 reference

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Tissue gold levels after chrysotherapy

5 July 2018

1 reference

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Multiplicity of adenosine 3',5'-monophosphate-dependent protein kinases from rat liver and mode of action of nucleoside 3',5'-monophosphate.

5 July 2018

1 reference

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Serum gold determinations in patients with rheumatoid arthritis receiving sodium aurothiomalate

5 July 2018

1 reference

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Serum gold. II. Levels in rheumatoid arthritis

5 July 2018

1 reference

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Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g

5 July 2018

1 reference

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Activators of protein kinase C down-regulate and phosphorylate the T3/T-cell antigen receptor complex of human T lymphocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295882

Reduction of peripheral blood lymphocytes in patients receiving gold therapy for rheumatoid arthritis

5 July 2018

1 reference

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Regulation of cellular function by products of lysosomal enzyme activity: elimination of human natural killer cells by a dipeptide methyl ester generated from L-leucine methyl ester by monocytes or polymorphonuclear leukocytes

5 July 2018

1 reference

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The complete primary structure of protein kinase C--the major phorbol ester receptor

5 July 2018

1 reference

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Cellular and molecular pharmacology of auranofin and related gold complexes

5 July 2018

1 reference

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Inhibition of human endothelial cell proliferation by gold compounds

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295882

The molecular heterogeneity of protein kinase C and its implications for cellular regulation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295882

Inositol phosphates and cell signalling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295882

A protein kinase C pseudosubstrate peptide inhibits phosphorylation of the CD3 antigen in streptolysin-O-permeabilized human T lymphocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295882

Molecular signaling mechanisms in T-lymphocyte activation pathways: a review and future prospects

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295882

Protein kinase C and T cell activation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295882

Effects of gold sodium thiomalate and tenidap sodium (CP-66,248-2) on a model of macrophage differentiation using HL-60 cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295882

Heterogeneity of protein kinase C expression and regulation in T lymphocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295882

A synthetic peptide substrate for selective assay of protein kinase C

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295882

Inhibition of antigen- and mitogen-induced human lymphocyte proliferation by gold compounds

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295882

A hepatic soluble cyclic nucleotide-independent protein kinase. Stimulation by basic polypeptides

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295882

"Panning" for lymphocytes: a method for cell selection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295882

Monoclonal Antibodies Defining Distinctive Human T Cell Surface Antigens

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295882

Lymphocyte involvement in rheumatoid arthritis. Studies during thoracic duct drainage

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295882

Chrysotherapy. suppression of immunoglobulin synthesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295882

Inhibitory action of chlorpromazine, dibucaine, and other phospholipid-interacting drugs on calcium-activated, phospholipid-dependent protein kinase.

5 July 2018

1 reference

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Two populations of Ia-like molecules on a human B cell line.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295882

Gold inhibition of the production of the second complement component by lymphokine-stimulated human monocytes.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295882

Monomorphic anti-HLA-A,B,C monoclonal antibodies detecting molecular subunits and combinatorial determinants.

28 October 2018

1 reference

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Antiarthritic properties and unique pharmacologic profile of a potential chrysotherapeutic agent: S K & F D-30162

28 October 2018

1 reference

12 December 2020

Specific therapy for rheumatoid arthritis

1 reference

12 December 2020

Blood and urine gold levels during chrysotherapy for rheumatoid arthritis

1 reference

12 December 2020

Effects of gold coordination complexes on neutrophil function are mediated via inhibition of protein kinase C

1 reference

12 December 2020

Inhibitory effects of anti-CD2 monoclonal antibodies on interleukin 2 production and interleukin 2 receptor expression in anti-CD3-induced T cell activation

1 reference

12 December 2020

Inhibition of protein kinase C activity by the antirheumatic drug auranofin

1 reference

12 December 2020

Effect of metal containing compounds on superoxide release from phorbol myristate acetate stimulated murine peritoneal macrophages: inhibition by auranofin and spirogermanium

1 reference

12 December 2020

Inhibition of in vitro proliferative response of cultured T lymphocytes to interleukin-2 by gold sodium thiomalate

1 reference

12 December 2020

Properties of protein kinase C subspecies in human platelets

1 reference

12 December 2020

Mode of activation and kinetic properties of three distinct forms of protein kinase C from rat brain

1 reference

12 December 2020

Isolation of protein kinase C subspecies from a preparation of human T lymphocytes

1 reference

12 December 2020

Immunohistochemical studies of interleukin-2 and gamma-interferon in rheumatoid arthritis

1 reference

12 December 2020

T cell activation: differences in the signals required for IL 2 production by nonactivated and activated T cells

1 reference

12 December 2020

Oral gold. Antiarthritic properties of alkylphosphinegold coordination complexes

1 reference

12 December 2020

Tissue gold concentration in a rheumatoid arthritic receiving chrysotherapy

1 reference

12 December 2020

Gold determination in biological fluids by atomic absorption spectrophotometry: application to chrysotherapy in rheumatoid arthritis patients

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12 December 2020

Do drugs change the course of rheumatoid arthritis?

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12 December 2020

Relationships between HLA-DR-expressing Cells and T Lymphocytes of Different Subsets in Rheumatoid Synovial Tissue

1 reference

12 December 2020

Salt-induced conformational changes in the catalytic subunit of adenosine 3',5'-phosphate dependent protein kinase. Use for establishing a connection between one sulfhydryl group and the .gamma.-P subsite in the ATP site of this subunit

1 reference

12 December 2020

Proteolytic activation of calcium-activated, phospholipid-dependent protein kinase by calcium-dependent neutral protease

1 reference

12 December 2020

An immunohistological analysis of lymphocyte subpopulations and their microenvironment in the synovial membranes of patients with rheumatoid arthritis using monoclonal antibodies

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12 December 2020

Comparative pharmacology and biological effects of different gold compounds

1 reference

12 December 2020

Comparative pharmacokinetics of parenteral and oral gold compounds

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12 December 2020

Identifiers

DOI

10.1172/JCI115788

1 reference

31 July 2017

1 reference

31 July 2017

1 reference