Etiology of pancreatic cancer, with a hypothesis concerning the role of N-nitroso compounds and excess gastric acidity (Q34210717)

31 July 2017

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title

Etiology of pancreatic cancer, with a hypothesis concerning the role of N-nitroso compounds and excess gastric acidity (English)

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31 July 2017

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Harvey A Risch

1

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PubMed ID

12837831

31 July 2017

language of work or name

English

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publication date

1 July 2003

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Journal of the National Cancer Institute

31 July 2017

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31 July 2017

95

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31 July 2017

13

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31 July 2017

948-960

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Prevalence and penetrance of germline BRCA1 and BRCA2 mutations in a population series of 649 women with ovarian cancer

31 July 2017

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.948

Pancreatic cancer: development of a unifying etiologic concept.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.948

Familial risk of pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.948

Identification of tobacco-derived compounds in human pancreatic juice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.948

Metabolism and activation of pancreas specific nitrosamines by pancreatic ductal cells in culture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.948

Anin vitro model of human pancreas carcinogenesis: Effects of nitroso compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.948

Volatile N-nitrosamines in gastric juice of patients with various conditions of the gastrointestinal tract determined by gas chromatography-mass spectrometry and related to intragastric pH and nitrate and nitrite levels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.948

Formation of nitrosamines during consumption of nitrate- and amine-rich foods, and the influence of the use of mouthwashes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.948

Assessment of exposure to carcinogenic N-nitrosamines in the rubber industry

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.948

N -Nitrosamines in the Rubber and Tire Industry

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.948

Exposure to high concentrations of nitrosamines and cancer mortality among a cohort of rubber workers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.948

O6-methylguanine DNA adducts associated with occupational nitrosamine exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.948

7-Methylguanine levels in DNA of smokers' and non-smokers' total white blood cells, granulocytes and lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.948

N-Nitroso compounds and human cancer. A molecular epidemiologic approach.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.948

N-nitroso compounds in fresh gastric juice and their relation to intragastric pH and nitrite employing an improved analytical method.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.948

Diet and other risk factors for cancer of the pancreas

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.948

Dietary and nutritional factors and pancreatic cancer: a case-control study based on direct interviews.

21 January 2018

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https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.948

A cohort study of smoking, alcohol consumption, and dietary factors for pancreatic cancer (United States).

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.948

Plasma secretin and pancreatic bicarbonate response to exogenous secretin in man

21 January 2018

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Acidity at different sites in the proximal duodenum of normal subjects and patients with duodenal ulcer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.948

Gastric ulcers differ from duodenal ulcers. Evaluation of basal acid output

21 January 2018

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pH of the contents of the duodenal bulb in relation to duodenal ulcer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.948

Eradicating Helicobacter pylori infection lowers gastrin mediated acid secretion by two thirds in patients with duodenal ulcer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.948

The risk of stomach cancer in patients with gastric or duodenal ulcer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.948

Cancer occurrence in a cohort of patients surgically treated for peptic ulcer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.948

Dietary habits and past medical history as related to fatal pancreas cancer risk among adventists

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.948

Increased risk of cancer at multiple sites after gastric surgery for peptic ulcer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.948

Death from malignant disease after surgery for duodenal ulcer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.948

Diabetes mellitus, other medical conditions and familial history of cancer as risk factors for pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.948

Relation between gastric histology and gastric juice pH and nitrite and N-nitroso compound concentrations in the stomach after surgery for duodenal ulcer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.948

Seroconversion and seroreversion in IgG antibodies to Helicobacter pylori: a serology based prospective cohort study

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.948

Evidence that cagA(+) Helicobacter pylori strains are disappearing more rapidly than cagA(-) strains

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.948

Helicobacter pylori infection and the risk for duodenal and gastric ulceration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.948

Histologic findings and Helicobacter pylori in duodenal biopsies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.948

Helicobacter pylori and atrophic gastritis: importance of the cagA status

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.948

Helicobacter pylori in the stomach--a paradox unmasked

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.948

The importance of interleukin 1beta in Helicobacter pylori associated disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.948

Effect of Helicobacter pylori on gastric somatostatin in duodenal ulcer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.948

Gastrin and somatostatin in Helicobacter pylori infected antral mucosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.948

Light and electron microscopic immunohistochemical investigation on G and D cells in antral mucosa in Helicobacter pylori-related gastritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.948

Helicobacter pylori lipopolysaccharide stimulates histamine release and DNA synthesis in rat enterochromaffin-like cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.948

Effect of Helicobacter pylori infection on gastrointestinal motility, pancreatic secretion and hormone release in asymptomatic humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.948

Experimental pancreatic hyperplasia and neoplasia: effects of dietary and surgical manipulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.948

Association between Helicobacter pylori infection and pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.948

Helicobacter pylori seropositivity as a risk factor for pancreatic cancer

21 January 2018

1 reference

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Helicobacter pylori and the risk of benign and malignant biliary tract disease

21 January 2018

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https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.948

Interleukin 1 beta and tumour necrosis factor alpha inhibit acid secretion in cultured rabbit parietal cells by multiple pathways

21 January 2018

1 reference

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Effects of pro-inflammatory cytokines on acid secretion

21 January 2018

1 reference

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Interleukin-1 polymorphisms associated with increased risk of gastric cancer

21 January 2018

1 reference

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Helicobacter pylori and interleukin 1 genotyping: an opportunity to identify high-risk individuals for gastric carcinoma

21 January 2018

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Cadmium content of vegetable foods in the effective range of a lead smelting plant

21 January 2018

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Dietary intake, levels in food and estimated intake of lead, cadmium, and mercury

21 January 2018

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Occupational exposures and pancreatic cancer: a meta-analysis

21 January 2018

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Heterocyclic amine content in beef cooked by different methods to varying degrees of doneness and gravy made from meat drippings.

21 January 2018

1 reference

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Carcinogenicity of heterocyclic amines for the pancreatic duct epithelium in hamsters.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.948

Genetic polymorphism of N-acetyltransferases, glutathione S-transferase M1 and NAD(P)H:quinone oxidoreductase in relation to malignant and benign pancreatic disease risk

21 January 2018

1 reference

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Dietary and other methyl-group availability factors and pancreatic cancer risk in a cohort of male smokers

21 January 2018

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Pancreatic cancer risk and nutrition-related methyl-group availability indicators in male smokers

21 January 2018

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The potential role of lycopene for human health

21 January 2018

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Risk factors for pancreatic cancer: an exploratory study

21 January 2018

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https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.948

Association between nonsteroidal anti-inflammatory drug use and the incidence of pancreatic cancer

21 January 2018

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Abnormal glucose metabolism and pancreatic cancer mortality

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.948

Physical activity, obesity, height, and the risk of pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.948

Insulin secretion as a determinant of pancreatic cancer risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.948

Dietary sugar, glycemic load, and pancreatic cancer risk in a prospective study

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.948

Insulin inhibits secretin-induced pancreatic bicarbonate output via cholinergic mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.948

Nutrient intake and cancer of the pancreas: a case-control study in Athens, Greece

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.948

21 January 2018

Identifiers

DOI

10.1093/JNCI/95.13.948

1 reference

31 July 2017

1 reference

PubMed ID

12837831