Cereblon expression is required for the antimyeloma activity of lenalidomide and pomalidomide. (Q34210005)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21860026%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

title

Cereblon expression is required for the antimyeloma activity of lenalidomide and pomalidomide (English)

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11 February 2020

9

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11

Robert Z Orlowski

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11 February 2020

author name string

Yuan Xiao Zhu

1

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11 February 2020

Esteban Braggio

2

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11 February 2020

Chang-Xin Shi

3

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11 February 2020

Laura A Bruins

4

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11 February 2020

Jessica E Schmidt

5

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11 February 2020

Scott Van Wier

6

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11 February 2020

Xiu-Bao Chang

7

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11 February 2020

Chad C Bjorklund

8

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11 February 2020

P Leif Bergsagel

10

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11 February 2020

A Keith Stewart

12

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11 February 2020

language of work or name

English

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publication date

22 August 2011

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11 February 2020

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11 February 2020

volume

118

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11 February 2020

page(s)

4771-4779

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11 February 2020

issue

18

1 reference

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Lenalidomide downregulates the cell survival factor, interferon regulatory factor-4, providing a potential mechanistic link for predicting response

11 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208291

IMiD immunomodulatory compounds block C/EBP{beta} translation through eIF4E down-regulation resulting in inhibition of MM.

5 July 2018

1 reference

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Evidence of a role for activation of Wnt/beta-catenin signaling in the resistance of plasma cells to lenalidomide

5 July 2018

1 reference

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Recent advances of IMiDs in cancer therapy

5 July 2018

1 reference

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Identification of a primary target of thalidomide teratogenicity

5 July 2018

1 reference

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Kinome-wide RNAi studies in human multiple myeloma identify vulnerable kinase targets, including a lymphoid-restricted kinase, GRK6.

5 July 2018

1 reference

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Mechanism of action of immunomodulatory drugs (IMiDS) in multiple myeloma

5 July 2018

1 reference

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Identification of copy number abnormalities and inactivating mutations in two negative regulators of nuclear factor-kappaB signaling pathways in Waldenstrom's macroglobulinemia

5 July 2018

1 reference

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IRF4 addiction in multiple myeloma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208291

Identification of kinetin riboside as a repressor of CCND1 and CCND2 with preclinical antimyeloma activity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208291

Improved survival in multiple myeloma and the impact of novel therapies

5 July 2018

1 reference

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The genomic landscapes of human breast and colorectal cancers

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208291

A randomized phase 2 study of lenalidomide therapy for patients with relapsed or relapsed and refractory multiple myeloma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208291

Efficient calculation of interval scores for DNA copy number data analysis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208291

Combination therapy with lenalidomide plus dexamethasone (Rev/Dex) for newly diagnosed myeloma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208291

Thalidomide is an inhibitor of angiogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208291

Improved survival of patients with multiple myeloma after the introduction of novel agents and the applicability of the International Staging System (ISS): an analysis of the Greek Myeloma Study Group (GMSG).

5 July 2018

1 reference

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The evolution of thalidomide and its IMiD derivatives as anticancer agents

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208291

10.1182/BLOOD-2011-05-356063

28 October 2018

Identifiers

DOI

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11 February 2020

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11 February 2020

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