Imprint of somatic hypermutation differs in human immunoglobulin heavy and lambda chain variable gene segments (Q34197279)

31 July 2017

title

Imprint of somatic hypermutation differs in human immunoglobulin heavy and lambda chain variable gene segments (English)

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31 July 2017

Jo Spencer

3

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ORCID Public Data File 2021

author name string

Laurent Boursier

series ordinal

1

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31 July 2017

Wen Su

series ordinal

2

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31 July 2017

publication date

1 June 2003

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31 July 2017

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31 July 2017

volume

39

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31 July 2017

issue

16

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31 July 2017

page(s)

1025-1034

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5'-Deoxyribose phosphate lyase activity of human DNA polymerase iota in vitro

31 July 2017

cites work

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Maturation of the immune response in germinal centers

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7 January 2021

Sequence analysis of light chain genes from human intestinal plasma cells demonstrates that lambda genes are almost all in-frame and highly mutated and most kappa genes are highly mutatedwhen in-frame and minimally mutated when out-of-frame

1 reference

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7 January 2021

Enhanced evolvability in immunoglobulin V genes under somatic hypermutation

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7 January 2021

Altering the pathway of immunoglobulin hypermutation by inhibiting uracil-DNA glycosylase.

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7 January 2021

Hypermutation, diversity and dissemination of human intestinal lamina propria plasma cells

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7 January 2021

Induction of somatic hypermutation in immunoglobulin genes is dependent on DNA polymerase iota.

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7 January 2021

Immunology: the roots of antibody diversity

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7 January 2021

Codon bias and plasticity in immunoglobulins

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7 January 2021

Hypermutation in shark immunoglobulin light chain genes results in contiguous substitutions

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7 January 2021

Both DNA strands of antibody genes are hypermutation targets

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7 January 2021

Targeting and selection of mutations in human Vlambda rearrangements

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7 January 2021

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

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7 January 2021

Genetic plasticity of V genes under somatic hypermutation: statistical analyses using a new resampling-based methodology

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7 January 2021

Correlation of somatic hypermutation specificity and A-T base pair substitution errors by DNA polymerase eta during copying of a mouse immunoglobulin kappa light chain transgene.

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7 January 2021

AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification

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7 January 2021

Increased hypermutation at G and C nucleotides in immunoglobulin variable genes from mice deficient in the MSH2 mismatch repair protein

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7 January 2021

Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice

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7 January 2021

Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)

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7 January 2021

Somatic hypermutagenesis in immunoglobulin genes. II. Influence of neighbouring base sequences on mutagenesis

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7 January 2021

Somatic mutation hotspots correlate with DNA polymerase eta error spectrum.

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7 January 2021

Evolution of Ig DNA sequence to target specific base positions within codons for somatic hypermutation

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7 January 2021

Codon bias targets mutation.

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7 January 2021

Somatic hypermutation in MutS homologue (MSH)3-, MSH6-, and MSH3/MSH6-deficient mice reveals a role for the MSH2-MSH6 heterodimer in modulating the base substitution pattern

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2803%2900033-6

7 January 2021

Altered spectra of hypermutation in antibodies from mice deficient for the DNA mismatch repair protein PMS2

1 reference

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7 January 2021

Targeting of non-Ig sequences in place of the V segment by somatic hypermutation.

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2803%2900033-6

7 January 2021

DNA polymerase eta is an A-T mutator in somatic hypermutation of immunoglobulin variable genes

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2803%2900033-6

7 January 2021

10.1016/S0161-5890(03)00033-6

Identifiers

DOI

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31 July 2017

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