Disrupted in renal carcinoma 2 (DIRC2), a novel transporter of the lysosomal membrane, is proteolytically processed by cathepsin L. (Q34194342)

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5 February 2020

title

Disrupted in renal carcinoma 2 (DIRC2), a novel transporter of the lysosomal membrane, is proteolytically processed by cathepsin L (English)

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5 February 2020

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Lalu Rudyat Telly Savalas

1

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Thomas Reinheckel

8

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author name string

Bruno Gasnier

2

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Markus Damme

3

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Torben Lübke

4

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Christian Wrocklage

5

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5 February 2020

Cécile Debacker

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5 February 2020

Adrien Jézégou

7

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Andrej Hasilik

9

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Paul Saftig

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Bernd Schröder

11

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language of work or name

English

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publication date

1 October 2011

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5 February 2020

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5 February 2020

volume

439

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issue

1

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5 February 2020

page(s)

113-128

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Lysosome biogenesis and lysosomal membrane proteins: trafficking meets function

5 February 2020

cites work

1 reference

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The proteome of lysosomes

21 January 2018

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Molecular physiology and pathophysiology of lysosomal membrane transporters

21 January 2018

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Integral and associated lysosomal membrane proteins

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Ins and outs of major facilitator superfamily antiporters.

21 January 2018

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Structure and mechanism of the lactose permease of Escherichia coli

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Structure and mechanism of the glycerol-3-phosphate transporter from Escherichia coli

21 January 2018

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Disruption of a novel MFS transporter gene, DIRC2, by a familial renal cell carcinoma-associated t(2;3)(q35;q21).

21 January 2018

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Enhanced degradation of cathepsin D synthesized in the presence of the threonine analog beta-hydroxynorvaline

21 January 2018

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Molecular basis for K(ATP) assembly: transmembrane interactions mediate association of a K+ channel with an ABC transporter

21 January 2018

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Identification of mammalian proline transporter SIT1 (SLC6A20) with characteristics of classical system imino

21 January 2018

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Cathepsin L deficiency as molecular defect of furless: hyperproliferation of keratinocytes and pertubation of hair follicle cycling

21 January 2018

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Role of cathepsin B in intracellular trypsinogen activation and the onset of acute pancreatitis

21 January 2018

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Human cathepsin L rescues the neurodegeneration and lethality in cathepsin B/L double-deficient mice.

21 January 2018

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Molecular characterisation of 'transmembrane protein 192' (TMEM192), a novel protein of the lysosomal membrane

21 January 2018

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

21 January 2018

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NCU-G1 is a highly glycosylated integral membrane protein of the lysosome

21 January 2018

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Presence of detergent-resistant microdomains in lysosomal membranes

21 January 2018

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Multiple targets for brefeldin A.

21 January 2018

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Cathepsin L. A New Proteinase from Rat-Liver Lysosomes

21 January 2018

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Cysteine cathepsins: cellular roadmap to different functions

21 January 2018

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CA-074, but not its methyl ester CA-074Me, is a selective inhibitor of cathepsin B within living cells

21 January 2018

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Cathepsin L and cathepsin B mediate reovirus disassembly in murine fibroblast cells

21 January 2018

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Identification and characterization of a lysosomal transporter for small neutral amino acids

21 January 2018

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Cystinosin, the protein defective in cystinosis, is a H(+)-driven lysosomal cystine transporter

21 January 2018

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Functional characterization of wild-type and mutant human sialin

21 January 2018

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The extent of polylactosamine glycosylation of MDCK LAMP-2 is determined by its Golgi residence time

21 January 2018

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Signals for sorting of transmembrane proteins to endosomes and lysosomes

21 January 2018

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Cysteine34 of the cytoplasmic tail of the cation-dependent mannose 6-phosphate receptor is reversibly palmitoylated and required for normal trafficking and lysosomal enzyme sorting

21 January 2018

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Principles of lysosomal membrane degradation: Cellular topology and biochemistry of lysosomal lipid degradation

21 January 2018

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Analysis of the biogenesis of heparan sulfate acetyl-CoA:alpha-glucosaminide N-acetyltransferase provides insights into the mechanism underlying its complete deficiency in mucopolysaccharidosis IIIC

21 January 2018

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Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9

21 January 2018

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Processing and activation of lysosomal proteinases

21 January 2018

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Towards specific functions of lysosomal cysteine peptidases: phenotypes of mice deficient for cathepsin B or cathepsin L.

21 January 2018

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Specialized roles for cysteine cathepsins in health and disease.

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Dilated cardiomyopathy in mice deficient for the lysosomal cysteine peptidase cathepsin L.

21 January 2018

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Lysosomal pathology and osteopetrosis upon loss of H+-driven lysosomal Cl- accumulation

21 January 2018

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Chimeric transcript discovery by paired-end transcriptome sequencing

21 January 2018

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The Slow, Tight-Binding Inhibition of Cathepsin B by Leupeptin. A Hysteretic Effect

21 January 2018

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21 January 2018

Identifiers

DOI

10.1042/BJ20110166

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21692750%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

1 reference