Metabolic therapy in the treatment of ischaemic heart disease: the pharmacology of trimetazidine (Q34187196)

31 July 2017

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title

Metabolic therapy in the treatment of ischaemic heart disease: the pharmacology of trimetazidine (English)

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arteriosclerotic heart disease

31 July 2017

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William C Stanley

1

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PubMed ID

12667223

31 July 2017

Mario Marzilli

series ordinal

2

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31 July 2017

1 April 2003

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Fundamental and Clinical Pharmacology

31 July 2017

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31 July 2017

17

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31 July 2017

2

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31 July 2017

133-145

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Effects of glucose and fatty acids on myocardial ischaemia and arrhythmias

31 July 2017

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https://api.crossref.org/works/10.1046%2FJ.1472-8206.2003.00154.X

Effect of a nicotinic-acid analogue on raised plasma-free-fatty-acids after acute myocardial infarction.

21 January 2018

1 reference

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Control of ventricular arrhythmias during myocardial infarction by antilipolytic treatment using a nicotinic-acid analogue

21 January 2018

1 reference

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Alterations of carbohydrate and lipid metabolism in the acutely ischemic heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1472-8206.2003.00154.X

Regulation of myocardial carbohydrate metabolism under normal and ischaemic conditions. Potential for pharmacological interventions

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1472-8206.2003.00154.X

Mitochondrial preference for short chain fatty acid oxidation during coronary artery constriction

21 January 2018

1 reference

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Regulation of fatty acid oxidation in the mammalian heart in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1472-8206.2003.00154.X

Cardiac fatty acid uptake and transport in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1472-8206.2003.00154.X

beta-oxidation of fatty acids in mitochondria, peroxisomes, and bacteria: a century of continued progress

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1472-8206.2003.00154.X

The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1472-8206.2003.00154.X

Relative importance of pyruvate dehydrogenase interconversion and feed-back inhibition in the effect of fatty acids on pyruvate oxidation by rat heart mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1472-8206.2003.00154.X

Active and inactive forms of pyruvate dehydrogenase in rat heart and kidney: effect of diabetes, fasting, and refeeding on pyruvate dehydrogenase interconversion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1472-8206.2003.00154.X

Pyruvate dehydrogenase activity and malonyl CoA levels in normal and ischemic swine myocardium: effects of dichloroacetate.

21 January 2018

1 reference

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New look to an old symptom: angina pectoris

21 January 2018

1 reference

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Molecular basis of electrocardiographic ST-segment elevation

21 January 2018

1 reference

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Effects of pH on the myofilaments and the sarcoplasmic reticulum of skinned cells from cardiace and skeletal muscles

21 January 2018

1 reference

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Amiloride delays the ischemia-induced rise in cytosolic free calcium

21 January 2018

1 reference

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Some biochemical aspects of the protective effect of trimetazidine on rat cardiomyocytes during hypoxia and reoxygenation

21 January 2018

1 reference

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The antianginal drug trimetazidine shifts cardiac energy metabolism from fatty acid oxidation to glucose oxidation by inhibiting mitochondrial long-chain 3-ketoacyl coenzyme A thiolase

21 January 2018

1 reference

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Influence of trimetazidine on the synthesis of complex lipids in the heart and other target organs

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1472-8206.2003.00154.X

Evidence for the existence of [3H]-trimetazidine binding sites involved in the regulation of the mitochondrial permeability transition pore

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1472-8206.2003.00154.X

[(3)H]-trimetazidine mitochondrial binding sites: regulation by cations, effect of trimetazidine derivatives and other agents and interaction with an endogenous substance

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1472-8206.2003.00154.X

Characteristics of a contemporary population with angina pectoris. TIDES Investigators.

21 January 2018

1 reference

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Residual myocardial ischaemia in first non-Q versus Q wave infarction: maximal exercise testing and ambulatory ST-segment monitoring

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1472-8206.2003.00154.X

Trimetazidine: a new concept in the treatment of angina. Comparison with propranolol in patients with stable angina. Trimetazidine European Multicenter Study Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1472-8206.2003.00154.X

Combination treatment in stable effort angina using trimetazidine and metoprolol: results of a randomized, double-blind, multicentre study (TRIMPOL II). TRIMetazidine in POLand

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1472-8206.2003.00154.X

Regulation of energy substrate metabolism in the diabetic heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1472-8206.2003.00154.X

Management of ischaemic heart disease in diabetic patients--is there a role for cardiac metabolic agents?

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1472-8206.2003.00154.X

Energy metabolism in the normal and failing heart: potential for therapeutic interventions

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1472-8206.2003.00154.X

Effects of trimetazidine on ischemic left ventricular dysfunction in patients with coronary artery disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1472-8206.2003.00154.X

Effects of trimetazidine on the contractile response of chronically dysfunctional myocardium to low-dose dobutamine in ischaemic cardiomyopathy

21 January 2018

1 reference

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Meta-analysis of Trials Comparing β-Blockers, Calcium Antagonists, and Nitrates for Stable Angina

21 January 2018

1 reference

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10.1046/J.1472-8206.2003.00154.X

21 January 2018

Identifiers

DOI

1 reference

31 July 2017

1 reference

PubMed ID

12667223