Epoxygenase metabolites. Epithelial and vascular actions (Q34185568)

31 July 2017

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title

Epoxygenase metabolites. Epithelial and vascular actions (English)

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31 July 2017

Imig JD

1

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31 July 2017

1 November 2000

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31 July 2017

Molecular Biotechnology

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31 July 2017

16

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31 July 2017

3

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31 July 2017

233-251

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https://scigraph.springernature.com/pub.10.1385/mb:16:3:233

31 July 2017

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cites work

Calcium influx factor, further evidence it is 5, 6-epoxyeicosatrienoic acid

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12 December 2020

Identification of epoxyeicosatrienoic acids as endothelium-derived hyperpolarizing factors

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12 December 2020

Cloning, sequencing, and cDNA-directed expression of the rat renal CYP4A2: arachidonic acid omega-hydroxylation and 11,12-epoxidation by CYP4A2 protein

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12 December 2020

Cytochrome P-450 arachidonate metabolites in rat kidney: characterization and hemodynamic responses

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12 December 2020

Cytochrome P450 and cyclooxygenase metabolites contribute to the endothelin-1 afferent arteriolar vasoconstrictor and calcium responses

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12 December 2020

Arachidonic acid metabolism modulates vasopressin-induced renal vasoconstriction

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12 December 2020

Molecular characterization of an arachidonic acid epoxygenase in rat brain astrocytes

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12 December 2020

Possible involvement of arachidonic acid metabolites of cytochrome P450 monooxygenase pathway in vasopressin-stimulated glycogenolysis in isolated rat hepatocytes

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12 December 2020

11,12-Epoxyeicosatrienoic acid stimulates endogenous mono-ADP-ribosylation in bovine coronary arterial smooth muscle

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12 December 2020

Epoxyeicosatrienoic acids, potassium channel blockers and endothelium-dependent hyperpolarization in the guinea-pig carotid artery

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12 December 2020

Effects of epoxyeicosatrienoic acids on isolated hearts and ventricular myocytes

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12 December 2020

Epoxyeicosatrienoic acids activate a high-conductance, Ca(2+)-dependent K + channel on pig coronary artery endothelial cells

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12 December 2020

Cerebral microvascular endothelial cell tube formation: role of astrocytic epoxyeicosatrienoic acid release

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12 December 2020

Effect of protein kinase C modulators on 14,15-epoxyeicosatrienoic acid incorporation into astroglial phospholipids.

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12 December 2020

Stimulation of prostaglandin G/H synthase-2 expression by arachidonic acid monoxygenase product, 14,15-epoxyeicosatrienoic acid

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12 December 2020

Regional distribution and expression modulation of cytochrome P-450 and epoxide hydrolase mRNAs in the rat brain

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12 December 2020

CDNA cloning, heterologous expression, and characterization of rat intestinal CYP2J4

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12 December 2020

Beta-oxidation of eicosanoids

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12 December 2020

5,6-Epoxyeicosatrienoic acid reduces increases in pulmonary vascular resistance in the dog.

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12 December 2020

Nitric oxide-independent suppression of P450 2C11 expression by interleukin-1beta and endotoxin in primary rat hepatocytes

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12 December 2020

Purification and characterization of rabbit small intestinal cytochromes P450 belonging to CYP2J and CYP4A subfamilies

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12 December 2020

Cytochrome P450 and the arachidonate cascade

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12 December 2020

Cyclooxygenase dependency of the renovascular actions of cytochrome P450-derived arachidonate metabolites.

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12 December 2020

Cytochrome P450 2C is an EDHF synthase in coronary arteries

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12 December 2020

Miconazole represses CO(2)-induced pial arteriolar dilation only under selected circumstances

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12 December 2020

Involvement of cytochrome P-450 enzyme activity in the control of microvascular permeability in canine lung

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12 December 2020

Cytochrome P450 metabolites of arachidonic acid in human placenta

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12 December 2020

Epoxyeicosatrienoic acids and dihydroxyeicosatrienoic acids are potent vasodilators in the canine coronary microcirculation.

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12 December 2020

Cytochrome P450 metabolites of arachidonic acid are potent inhibitors of vasopressin action on rabbit cortical collecting duct

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12 December 2020

In vivo location and mechanism of EDHF-mediated vasodilation in canine coronary microcirculation

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12 December 2020

Cytochrome P-450 pathway in renal function of normal rats and rats with bilateral ureteral obstruction

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12 December 2020

14,15-Epoxyeicosatrienoic acid metabolism in endothelial cells.

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12 December 2020

Functional role of epoxyeicosatrienoic acids and their production in astrocytes: approaches for gene transfer and therapy (review).

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12 December 2020

Inhibition of cardiac L-type calcium channels by epoxyeicosatrienoic acids

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12 December 2020

NO/PGI2-independent vasorelaxation and the cytochrome P450 pathway in rabbit carotid artery.

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12 December 2020

Identification, functional characterization, and regulation of a new cytochrome P450 subfamily, the CYP2Ns.

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12 December 2020

K(+) channel blockers and cytochrome P450 inhibitors on acetylcholine-induced, endothelium-dependent relaxation in rabbit mesenteric artery

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12 December 2020

Conversion of epoxyeicosatrienoic acids (EETs) to chain-shortened epoxy fatty acids by human skin fibroblasts

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12 December 2020

Oxygenation of arachidonic acid by hepatic microsomes of the rabbit. Mechanism of biosynthesis of two vicinal dihydroxyeicosatrienoic acids

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12 December 2020

Ketoconazole activates chloride and fluid secretion by Necturus gallbladder at low pH

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12 December 2020

Effects of ischemia-reperfusion on individual cytochrome P450 isoforms in the rat kidney

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12 December 2020

Biochemical characterization of the human liver cytochrome P450 arachidonic acid epoxygenase pathway

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12 December 2020

Synthesis of hydroxyeicosatetraenoic (HETEs) and epoxyeicosatrienoic acids (EETs) by cultured bovine coronary artery endothelial cells

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12 December 2020

Influence of epoxyeicosatrienoic acids on uterine function

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12 December 2020

Arachidonic acid diols produced by cytochrome P-450 monooxygenases are incorporated into phospholipids of vascular endothelial cells

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12 December 2020

Cytochrome P450 metabolites of arachidonic acid as intracellular signaling molecules in vascular tissue

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12 December 2020

Cloning and expression of murine CYP2Cs and their ability to metabolize arachidonic acid

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12 December 2020

Epoxide hydrolases regulate epoxyeicosatrienoic acid incorporation into coronary endothelial phospholipids

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12 December 2020

Inhibitors of alternative pathways of arachidonate metabolism differentially affect fever in mice.

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12 December 2020

Epoxyeicosatrienoic acids inhibit Ca2+ entry into platelets stimulated by thapsigargin and thrombin

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12 December 2020

Epoxygenase metabolites of arachidonic acid inhibit vasopressin response in toad bladder

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12 December 2020

Epoxyeicosatrienoic acids stimulate the growth of vascular smooth muscle cells

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12 December 2020

Induction of renal arachidonate cytochrome P-450 epoxygenase after uninephrectomy: counterregulation of hyperfiltration

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12 December 2020

Attenuation of endogenous oxidative stress-induced cell death by cytochrome P450 inhibitors in primary cultures of rat hepatocytes

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12 December 2020

Arachidonic acid modulation of alpha1H, a cloned human T-type calcium channel

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12 December 2020

Nutritional status modulates rat liver cytochrome P450 arachidonic acid metabolism.

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12 December 2020

Afferent arteriolar responses to ANG II involve activation of PLA2 and modulation by lipoxygenase and P-450 pathways

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12 December 2020

The role of the cytochrome P450-dependent metabolites of arachidonic acid in blood pressure regulation and renal function: a review

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12 December 2020

Epoxyeicosatrienoic acids constrict isolated pressurized rabbit pulmonary arteries

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12 December 2020

Arachidonic acid metabolism by human cytochrome P450s 2C8, 2C9, 2E1, and 1A2: regioselective oxygenation and evidence for a role for CYP2C enzymes in arachidonic acid epoxygenation in human liver microsomes

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12 December 2020

Dilation of cerebral arterioles by cytochrome P-450 metabolites of arachidonic acid

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12 December 2020

CYP2J subfamily P450s in the lung: expression, localization, and potential functional significance

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12 December 2020

Afferent arteriolar vasodilation to the sulfonimide analog of 11, 12-epoxyeicosatrienoic acid involves protein kinase A

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12 December 2020

Experimental and/or genetically controlled alterations of the renal microsomal cytochrome P450 epoxygenase induce hypertension in rats fed a high salt diet

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12 December 2020

Multiple arachidonic acid metabolites inhibit sodium-dependent phosphate transport in OK cells

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12 December 2020

Brain synthesis and cerebrovascular action of epoxygenase metabolites of arachidonic acid

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12 December 2020

Regulation of potassium channels in coronary arterial smooth muscle by endothelium-derived vasodilators

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12 December 2020

Modulation of cytochrome P-450 gene expression in endotoxemic mice is tissue specific and peroxisome proliferator-activated receptor-alpha dependent

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12 December 2020

Role of cytochrome P-450 epoxygenase metabolites in EGF signaling in renal proximal tubule

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12 December 2020

Nitric oxide and prostaglandins mediate vasodilation to 5,6-EET in rabbit lung

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12 December 2020

An epoxygenase metabolite of arachidonic acid 5,6 epoxy-eicosatrienoic acid mediates angiotensin-induced natriuresis in proximal tubular epithelium

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12 December 2020

Synthesis of lipoxygenase and epoxygenase products of arachidonic acid by normal and stenosed canine coronary arteries

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12 December 2020

Vasoactivity of arachidonic acid epoxides.

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12 December 2020

A keratinocyte-specific epoxygenase, CYP2B12, metabolizes arachidonic acid with unusual selectivity, producing a single major epoxyeicosatrienoic acid

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12 December 2020

Cytochrome P450 metabolites of arachidonic acid: rapid incorporation and hydration of 14,15-epoxyeicosatrienoic acid in arterial smooth muscle cells

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12 December 2020

Regulation of cytochrome P450 expression by sphingolipids.

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12 December 2020

Increased CYP2J expression and epoxyeicosatrienoic acid formation in spontaneously hypertensive rat kidney.

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12 December 2020

Epoxygenase metabolites of arachidonic acid affect electrophysiologic properties of rat tracheal epithelial cells1.

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12 December 2020

Origin and function of epoxyeicosatrienoic acids in vascular endothelial cells: more than just endothelium-derived hyperpolarizing factor?

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12 December 2020

Regulation of hepatic cytochrome P450 2C11 by glucocorticoids

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12 December 2020

Modulation of endothelium-dependent hyperpolarization and relaxation to acetylcholine in rat mesenteric artery by cytochrome P450 enzyme activity

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12 December 2020

Transfection of an active cytochrome P450 arachidonic acid epoxygenase indicates that 14,15-epoxyeicosatrienoic acid functions as an intracellular second messenger in response to epidermal growth factor.

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12 December 2020

Possible role of P-450 metabolite of arachidonic acid in vasodilator mechanism of angiotensin II type 2 receptor in the isolated microperfused rabbit afferent arteriole

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12 December 2020

Molecular cloning and expression of CYP2J2, a human cytochrome P450 arachidonic acid epoxygenase highly expressed in heart

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12 December 2020

Inhibition of brain P-450 arachidonic acid epoxygenase decreases baseline cerebral blood flow

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12 December 2020

Cytochrome P-450 arachidonic acid epoxygenase. Regulatory control of the renal epoxygenase by dietary salt loading

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12 December 2020

Role of PGI2 and epoxyeicosatrienoic acids in relaxation of bovine coronary arteries to arachidonic acid

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12 December 2020

Down-regulation of cytochrome P450 mRNAs and proteins in mice lacking a functional NOS2 gene

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12 December 2020

Phospholipase A2-mediated activation of mitogen-activated protein kinase by angiotensin II

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12 December 2020

Role of cytochrome P-450 enzymes and metabolites of arachidonic acid in the control of vascular tone

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12 December 2020

Arachidonic acid epoxygenase. Stereochemical analysis of the endogenous epoxyeicosatrienoic acids of human kidney cortex

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12 December 2020

Formation and actions of 20-hydroxyeicosatetraenoic acid in rat renal arterioles

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12 December 2020

Formation of epoxyeicosatrienoic acids from arachidonic acid by cultured rat aortic smooth muscle cell microsomes

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12 December 2020

Bioassay of an endothelium-derived hyperpolarizing factor from bovine coronary arteries: role of a cytochrome P450 metabolite

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12 December 2020

Renal effects of cP450 arachidonate metabolites in the Lyon hypertensive rat.

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12 December 2020

Cytochrome P450-dependent effects of bradykinin in the rat heart

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12 December 2020

Intracellular signaling in the regulation of renal Na-K-ATPase. II. Role of eicosanoids

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12 December 2020

Noncyclooxygenase metabolites of arachidonic acid amplify the vasopressin-induced Ca2+ signal in glomerular mesangial cells by releasing Ca2+ from intracellular stores

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12 December 2020

Renal vasodilator activity of 5,6-epoxyeicosatrienoic acid depends upon conversion by cyclooxygenase and release of prostaglandins

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12 December 2020

Liver microsomal cytochrome P-450 and the oxidative metabolism of arachidonic acid

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12 December 2020

Identification of arachidonate P-450 metabolites in human platelet phospholipids

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12 December 2020

Formation and metabolism of 14,15-epoxyeicosatrienoic acid by human reproductive tissues

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12 December 2020

14(R),15(S)-epoxyeicosatrienoic acid (14(R),15(S)-EET) receptor in guinea pig mononuclear cell membranes.

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12 December 2020

Cytochrome P450, the arachidonic acid cascade, and hypertension: new vistas for an old enzyme system

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12 December 2020

Contribution of NO and cytochrome P450 to the vasodilator effect of bradykinin in the rat kidney

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12 December 2020

Determination of 14,15-epoxyeicosatrienoic acid and 14,15-dihydroxyeicosatrienoic acid by fluoroimmunoassay

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12 December 2020

Stereoselective epoxidation of arachidonic acid by cytochrome P-450s 2CAA and 2C2.

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12 December 2020

The rabbit pulmonary cytochrome P450 arachidonic acid metabolic pathway: characterization and significance.

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12 December 2020

Molecular cloning, expression, and functional significance of a cytochrome P450 highly expressed in rat heart myocytes.

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12 December 2020

Mechanism of action of cerebral epoxyeicosatrienoic acids on cerebral arterial smooth muscle

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12 December 2020

Newborn piglet cerebral microvascular responses to epoxyeicosatrienoic acids

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12 December 2020

Actions of epoxygenase metabolites on the preglomerular vasculature.

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12 December 2020

Further investigation of endothelium-derived hyperpolarizing factor (EDHF) in rat hepatic artery: studies using 1-EBIO and ouabain

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12 December 2020

Epoxyeicosatrienoic acids stimulate glucagon and insulin release from isolated rat pancreatic islets

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12 December 2020

Evidence against a role of cytochrome P450-derived arachidonic acid metabolites in endothelium-dependent hyperpolarization by acetylcholine in rat isolated mesenteric artery

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12 December 2020

Pharmacological evaluation of an epoxide as the putative hyperpolarizing factor mediating the nitric oxide-independent vasodilator effect of bradykinin in the rat heart

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12 December 2020

Signaling mechanisms coupled to the angiotensin receptor of proximal tubular epithelium

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12 December 2020

An epoxygenase metabolite of arachidonic acid mediates angiotensin II-induced rises in cytosolic calcium in rabbit proximal tubule epithelial cells

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12 December 2020

CYP2J subfamily cytochrome P450s in the gastrointestinal tract: expression, localization, and potential functional significance

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12 December 2020

An active site substitution, F87V, converts cytochrome P450 BM-3 into a regio- and stereoselective (14S,15R)-arachidonic acid epoxygenase

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12 December 2020

Bioactivation of arachidonic acid by the cytochrome P450 monooxygenases of guinea pig lung: the orthologue of cytochrome P450 2B4 is solely responsible for formation of epoxyeicosatrienoic acids

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12 December 2020

Direct modulation of tracheal Cl--channel activity by 5,6- and 11,12-EET

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12 December 2020

Effects of epoxyeicosatrienoic acids on the cardiac sodium channels in isolated rat ventricular myocytes.

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12 December 2020

Functional implications of a newly characterized pathway of 11,12-epoxyeicosatrienoic acid metabolism in arterial smooth muscle

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12 December 2020

Defective expression of cytochrome P450 proteins in the liver of the genetically obese Zucker rat

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12 December 2020

Molecular cloning, enzymatic characterization, developmental expression, and cellular localization of a mouse cytochrome P450 highly expressed in kidney.

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12 December 2020

Potentiation of endothelium-dependent relaxation by epoxyeicosatrienoic acids

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12 December 2020

Intestinal vasodilation by epoxyeicosatrienoic acids: arachidonic acid metabolites produced by a cytochrome P450 monooxygenase

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12 December 2020

Contribution of cytochrome P450 epoxygenase and hydroxylase pathways to afferent arteriolar autoregulatory responsiveness

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12 December 2020

Role of P-450 arachidonic acid epoxygenase in the response of cerebral blood flow to glutamate in rats

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12 December 2020

Regio- and stereoselective epoxidation of arachidonic acid by human cytochromes P450 2C8 and 2C9.

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12 December 2020

Identification of the 11,14,15- and 11,12, 15-trihydroxyeicosatrienoic acids as endothelium-derived relaxing factors of rabbit aorta

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12 December 2020

5,6-EET inhibits ion transport in collecting duct by stimulating endogenous prostaglandin synthesis

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12 December 2020

Possible contribution of platelet cyclooxygenase to the renal vascular action of 5,6-epoxyeicosatrienoic acid

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12 December 2020

Antisense oligonucleotides against cytochrome P450 2C8 attenuate EDHF-mediated Ca(2+) changes and dilation in isolated resistance arteries.

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12 December 2020

A role for protein kinase C alpha in stimulation of prostaglandin G/H synthase-2 transcription by 14,15-epoxyeicosatrienoic acid

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12 December 2020

Molecular cloning, expression and characterization of an endogenous human cytochrome P450 arachidonic acid epoxygenase isoform

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12 December 2020

Effects of cytochrome P450 inhibitors on EDHF-mediated relaxation in the rat hepatic artery.

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12 December 2020

Metabolism of arachidonate through NADPH-dependent oxygenase of renal cortex

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12 December 2020

Molecular cloning, expression, and enzymatic characterization of the rat kidney cytochrome P-450 arachidonic acid epoxygenase

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12 December 2020

Epoxyeicosatrienoic acids relax airway smooth muscles and directly activate reconstituted KCa channels

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12 December 2020

Predominant expression of an arachidonate epoxygenase in islets of Langerhans cells in human and rat pancreas

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12 December 2020

Epoxyeicosatrienoic acids and their sulfonimide derivatives stimulate tyrosine phosphorylation and induce mitogenesis in renal epithelial cells

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12 December 2020

Cytochrome P-450-dependent arachidonate metabolites and renal functions in the Lyon hypertensive rat.

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12 December 2020

Cytochrome P-450 pathway in acetylcholine-induced canine coronary microvascular vasodilation in vivo

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12 December 2020

Epoxyeicosatrienoic acids activate K+ channels in coronary smooth muscle through a guanine nucleotide binding protein.

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12 December 2020

Stereospecific effects of epoxyeicosatrienoic acids on renal vascular tone and K(+)-channel activity

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12 December 2020

Regiospecific expression of cytochrome P-450s and microsomal epoxide hydrolase in human brain tissue

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12 December 2020

Differential inductive and suppressive effects of endotoxin and particulate irritants on hepatic and renal cytochrome P-450 expression

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12 December 2020

Metabolism of 5,6-epoxyeicosatrienoic acid by the human platelet. Formation of novel thromboxane analogs

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12 December 2020

Anti-inflammatory properties of cytochrome P450 epoxygenase-derived eicosanoids.

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12 December 2020

Identifiers

DOI

10.1385/MB:16:3:233

1 reference

PubMed ID

11252808

Dimensions Publication ID

31 July 2017

0 references

1 reference

PubMed ID

11252808