Acid-induced p16 hypermethylation contributes to development of esophageal adenocarcinoma via activation of NADPH oxidase NOX5-S. (Q34178797)

31 July 2017

Acid-induced p16 hypermethylation contributes to development of esophageal adenocarcinoma via activation of NADPH oxidase NOX5-S. (English)

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31 July 2017

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Jie Hong

1

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31 July 2017

Murray Resnick

2

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31 July 2017

Jose Behar

3

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31 July 2017

Li Juan Wang

4

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31 July 2017

Jack Wands

5

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31 July 2017

Ronald A DeLellis

6

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31 July 2017

Rhonda F Souza

7

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31 July 2017

Stuart J Spechler

8

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31 July 2017

Weibiao Cao

9

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31 July 2017

24 June 2010

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American Journal of Physiology - Gastrointestinal and Liver Physiology

31 July 2017

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31 July 2017

299

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31 July 2017

3

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31 July 2017

G697-706

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Role of a novel bile acid receptor TGR5 in the development of oesophageal adenocarcinoma

31 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950676

DNA promoter hypermethylation of p16 and APC predicts neoplastic progression in Barrett's esophagus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950676

A multicenter, double-blinded validation study of methylation biomarkers for progression prediction in Barrett's esophagus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950676

DNA hypermethylation regulates the expression of members of the Mu-class glutathione S-transferases and glutathione peroxidases in Barrett's adenocarcinoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950676

A methylation-specific and SYBR-green-based quantitative polymerase chain reaction technique for O6-methylguanine DNA methyltransferase promoter methylation analysis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950676

Characterization of telomerase-immortalized, non-neoplastic, human Barrett's cell line (BAR-T).

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950676

Esophageal acid exposure at pH < or = 2 is more common in Barrett's esophagus patients and is associated with oxidative stress

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950676

cAMP-response element-binding protein mediates acid-induced NADPH oxidase NOX5-S expression in Barrett esophageal adenocarcinoma cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950676

Detection of methylated apoptosis-associated genes in urine sediments of bladder cancer patients

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950676

Reflux, Barrett's oesophagus and adenocarcinoma: burning questions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950676

Chemical basis of inflammation-induced carcinogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950676

The superoxide-generating NADPH oxidase: structural aspects and activation mechanism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950676

Reactive oxygen species: are they involved in the pathogenesis of GERD, Barrett's esophagus, and the latter's progression toward esophageal cancer?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950676

A Ca(2+)-activated NADPH oxidase in testis, spleen, and lymph nodes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950676

Review article: a conceptual approach to understanding the molecular mechanisms of cancer development in Barrett's oesophagus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950676

p16(MTS-1/CDKN2/INK4a) in cancer progression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950676

MethyLight: a high-throughput assay to measure DNA methylation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950676

A mammalian H+ channel generated through alternative splicing of the NADPH oxidase homolog NOH-1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950676

Cell transformation by the superoxide-generating oxidase Mox1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950676

Dynamic effects of acid on Barrett's esophagus. An ex vivo proliferation and differentiation model

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950676

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950676

Overexpression of cyclin D1 enhances gene amplification

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950676

Subunit rearrangement of the cyclin-dependent kinases is associated with cellular transformation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950676

Barrett's esophagus, dysplasia, and adenocarcinoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950676

Extensive oxidative DNA damage in hepatocytes of transgenic mice with chronic active hepatitis destined to develop hepatocellular carcinoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950676

Free radicals and the etiology of colon cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950676

NOX5 NAD(P)H oxidase regulates growth and apoptosis in DU 145 prostate cancer cells

5 July 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00186.2010

MAPK mediates PKC-dependent contraction of cat esophageal and lower esophageal sphincter circular smooth muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00186.2010

Quantitative detection of methylated SOCS-1 , a tumor suppressor gene, by a modified protocol of quantitative real time methylation-specific PCR using SYBR green and its use in early gastric cancer detection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00186.2010

Proton pump inhibitors are associated with reduced incidence of dysplasia in Barrett's esophagus

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00186.2010

p16 expression in Barrett's esophagus and esophageal adenocarcinoma: association with genetic and epigenetic alterations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00186.2010

Epigenetic changes induced by reactive oxygen species in hepatocellular carcinoma: methylation of the E-cadherin promoter.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00186.2010

Intragenic mutations of CDKN2B and CDKN2A in primary human esophageal cancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00186.2010

Epigenetic patterns in the progression of esophageal adenocarcinoma

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950676

Fields of aberrant CpG island hypermethylation in Barrett's esophagus and associated adenocarcinoma.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950676

Symptomatic Gastroesophageal Reflux as a Risk Factor for Esophageal Adenocarcinoma

28 October 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00186.2010

p16(INK4a) lesions are common, early abnormalities that undergo clonal expansion in Barrett's metaplastic epithelium

21 January 2018

1 reference

12 December 2020

p16 inactivation by methylation of the CDKN2A promoter occurs early during neoplastic progression in Barrett's esophagus

1 reference

12 December 2020

Modes of silencing of p16 in development of esophageal squamous cell carcinoma

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12 December 2020

The MTS1 gene is frequently mutated in primary human esophageal tumors

1 reference

12 December 2020

p16INK4a promoter is hypermethylated at a high frequency in esophageal adenocarcinomas

1 reference

12 December 2020

Hypermethylation of the CDKN2/p16 promoter during neoplastic progression in Barrett's esophagus

1 reference

12 December 2020

Detection of aberrant p16 methylation in the plasma and serum of liver cancer patients

1 reference

12 December 2020

High incidence of allelic loss on chromosome 5 and inactivation of p15INK4B and p16INK4A tumor suppressor genes in oxystress-induced renal cell carcinoma of rats

1 reference

12 December 2020

Differentiation and proliferation in Barrett's esophagus and the effects of acid suppression

1 reference

12 December 2020

Identifiers

DOI

10.1152/AJPGI.00186.2010

1 reference

31 July 2017

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31 July 2017

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