The functions of the amyloid precursor protein gene. (Q34173160)

31 July 2017

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title

The functions of the amyloid precursor protein gene. (English)

1 reference

31 July 2017

Panegyres PK

1

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31 July 2017

1 January 2001

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Reviews in the Neurosciences

31 July 2017

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31 July 2017

12

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31 July 2017

1

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31 July 2017

1-39

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Induction of amyloid precursor protein mRNA after heat shock in cultured human lymphoblastoid cells.

31 July 2017

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Selective induction of Kunitz-type protease inhibitor domain-containing amyloid precursor protein mRNA after persistent focal ischemia in rat cerebral cortex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Axonal sprouting induced in the sciatic nerve by the amyloid precursor protein (APP) and other antiproteases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Expression of amyloid precursor protein mRNA isoforms in rat brain is differentially regulated during postnatal maturation and by cholinergic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Developmental and aging changes in the expression of amyloid precursor protein in Down syndrome brains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Increased expression of amyloid precursor protein and amyloid precursor-like protein 2 during trophic factor withdrawal-induced death of neuronal PC12 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

β-Amyloid stimulates glial cells in vitro to produce growth factors that accumulate in senile plaques in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Alzheimer disease amyloid beta protein forms calcium channels in bilayer membranes: blockade by tromethamine and aluminum

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Expression of amyloid precursor protein (beta-APP) in the neonatal brain following hypoxic ischaemic injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Particulate forms of APP in the extracellular milieu of cultured cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Plaque formation in brain transplants exposed to human beta-amyloid precursor protein 695.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Differential distribution of amyloid protein precursor immunoreactivity in the rat brain studied by using five different antibodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Proteolytic fragments of Alzheimer's disease-associated presenilin 1 are present in synaptic organelles and growth cone membranes of rat brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Amyloid beta peptide induces necrosis rather than apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Hydrogen peroxide mediates amyloid beta protein toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Thyroid hormone negatively regulates the transcriptional activity of the beta-amyloid precursor protein gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

The amyloid precursor protein is concentrated in neuronal lysosomes in normal and Alzheimer disease subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Regulation and expression of the Alzheimer's beta/A4 amyloid protein precursor in health, disease, and Down's syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Interaction of rat brain phosphofructokinase with Alzheimer's beta A4-amyloid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

The genetics of Alzheimer disease: current status and future prospects

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Alpha-2 macroglobulin is genetically associated with Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Staining of amyloid precursor protein to study axonal damage in mild head injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Identification of an evolutionarily conserved heterotrimeric protein complex involved in protein targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

The X11alpha protein slows cellular amyloid precursor protein processing and reduces Abeta40 and Abeta42 secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Expression of amyloid precursor protein in a neuronal cell line: functional activity of proximal regulatory elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

The helix-loop-helix transcription factor USF interacts with the basal promoter of human amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

APP-collagen interaction is mediated by a heparin bridge mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Inflammatory processes induce beta-amyloid precursor protein changes in mouse brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Amyloid precursor protein mRNA levels in the mononuclear blood cells of Alzheimer's and Down's patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Binding of secreted human neuroblastoma proteoglycans to the Alzheimer's amyloid A4 peptide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Alzheimer's amyloid precursor protein is expressed on the surface of hematopoietic cells upon activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

gamma-secretase cleavage is distinct from endoplasmic reticulum degradation of the transmembrane domain of the amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Rapid induction of Alzheimer A beta amyloid formation by zinc.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Cholinergic agonists and interleukin 1 regulate processing and secretion of the Alzheimer beta/A4 amyloid protein precursor

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Evidence that tumor necrosis factor alpha converting enzyme is involved in regulated alpha-secretase cleavage of the Alzheimer amyloid protein precursor

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Release of excess amyloid beta protein from a mutant amyloid beta protein precursor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Expression of the amyloid precursor protein of Alzheimer's disease on the surface of transfected HeLa cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Recombinant human amyloid precursor-like protein 2 (APLP2) expressed in the yeast Pichia pastoris can stimulate neurite outgrowth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Genetic modification of the phenotypes produced by amyloid precursor protein overexpression in transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Early-onset Alzheimer's disease caused by mutations at codon 717 of the beta-amyloid precursor protein gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Structural features of the 5' upstream regulatory region of the gene encoding rat amyloid precursor protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Bacterial expression, purification of full length and carboxyl terminal fragment of Alzheimer amyloid precursor protein and their proteolytic processing by thrombin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

APP-BP1, a novel protein that binds to the carboxyl-terminal region of the amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Heat shock alters Alzheimer's beta amyloid precursor protein expression in human endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Generation of amyloid beta protein from its precursor is sequence specific

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Additive effects of PS1 and APP mutations on secretion of the 42-residue amyloid beta-protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Secretion of nerve growth factor from septum stimulates neurite outgrowth and release of the amyloid protein precursor of Alzheimer's disease from hippocampal explants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Beta-amyloid(1-40) effects on behavior and memory.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Proteolytical processing of mutated human amyloid precursor protein in transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

apl-1, a Caenorhabditis elegans gene encoding a protein related to the human beta-amyloid protein precursor

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Amyloid beta-peptide (A beta P) potentiates a nimodipine-sensitive L-type barium conductance in N1E-115 neuroblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Brain endothelial cell enzymes cleave platelet-retained amyloid precursor protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Exchanging the extracellular domain of amyloid precursor protein for horseradish peroxidase does not interfere with alpha-secretase cleavage of the beta-amyloid region, but randomizes secretion in Madin-Darby canine kidney cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Transcriptional activation of Alzheimer's beta-amyloid precursor protein gene by stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Specific intercellular binding of the beta-amyloid precursor protein to the presenilins induces intercellular signaling: its significance for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Generation of beta A4 from the amyloid protein precursor and fragments thereof

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Cleavage of amyloid beta peptide during constitutive processing of its precursor

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Candidate gamma-secretases in the generation of the carboxyl terminus of the Alzheimer's disease beta A4 amyloid: possible involvement of cathepsin D.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Solubilization of beta-amyloid-(1-42)-peptide: reversing the beta-sheet conformation induced by aluminum with silicates

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Amyloid deposition is associated with c-Jun expression in Alzheimer's disease and amyloid angiopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Expression of the amyloid precursor protein gene in mouse oocytes and embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Topography of a binding site for small amnestic peptides deduced from structure-activity studies: relation to amnestic effect of amyloid beta protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Presenilin-1, amyloid precursor protein and amyloid precursor-like protein 2 mRNA levels in human superior frontal cortex during aging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Expression of amyloid precursor protein mRNAs in endothelial, neuronal and glial cells: modulation by interleukin-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Nerve growth factor does not influence the expression of beta amyloid precursor protein mRNA in rat brain: in vivo and in vitro studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Transgenic Drosophila expressing human amyloid precursor protein show gamma-secretase activity and a blistered-wing phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

pH-dependent structural transitions of Alzheimer amyloid peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Fibril formation by primate, rodent, and Dutch-hemorrhagic analogues of Alzheimer amyloid beta-protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Overexpression of amyloid precursor protein alters its normal processing and is associated with neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Intracellular production of beta A4 amyloid of Alzheimer's disease: modulation by phosphoramidon and lack of coupling to the secretion of the amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Two types of amyloid precursor protein (APP) mRNA in rat glioma cell lines: upregulation via a cyclic AMP-dependent pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

G protein betagamma complex-mediated apoptosis by familial Alzheimer's disease mutant of APP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

A glia-derived neurite promoting factor with protease inhibitory activity belongs to the protease nexins

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Expression of beta amyloid protein precursor mRNAs: recognition of a novel alternatively spliced form and quantitation in Alzheimer's disease using PCR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Interleukin 1 regulates synthesis of amyloid beta-protein precursor mRNA in human endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

K+ channel openers protect hippocampal neurons against oxidative injury and amyloid beta-peptide toxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Regulation of beta-amyloid precursor protein isoform mRNAs by transforming growth factor-beta 1 and interleukin-1 beta in astrocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Endoplasmic reticulum and trans-Golgi network generate distinct populations of Alzheimer beta-amyloid peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Brain interleukin 1 and S-100 immunoreactivity are elevated in Down syndrome and Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Microglial interleukin-1 alpha expression in human head injury: correlations with neuronal and neuritic beta-amyloid precursor protein expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Identification and characterization of a kappa B/Rel binding site in the regulatory region of the amyloid precursor protein gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Interleukin-1beta and glutamate activate the NF-kappaB/Rel binding site from the regulatory region of the amyloid precursor protein gene in primary neuronal cultures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Targeting of cell-surface beta-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Amyloid beta-peptide is produced by cultured cells during normal metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Cellular processing of beta-amyloid precursor protein and the genesis of amyloid beta-peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Synthetic Alzheimer amyloid beta/A4 peptides enhance production of complement C3 component by cultured microglial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Mouse cortical neurones lacking APP show normal neurite outgrowth and survival responses in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Apolipoprotein E and cholesterol affect neuronal calcium signalling: the possible relationship to beta-amyloid neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Presenile dementia and cerebral haemorrhage linked to a mutation at codon 692 of the beta-amyloid precursor protein gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Inhibition of platelet activation by the Alzheimer's disease amyloid precursor protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Differential regulation of amyloid-beta-protein mRNA expression within hippocampal neuronal subpopulations in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Transgenic mouse brain histopathology resembles early Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Human and rodent sequence analogs of Alzheimer's amyloid beta A4 share similar properties and can be solubilized in buffers of pH 7.4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Aggregation and secondary structure of synthetic amyloid beta A4 peptides of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

The alternatively spliced Kunitz protease inhibitor domain alters amyloid beta protein precursor processing and amyloid beta protein production in cultured cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

The rat amyloid precursor protein promoter contains two DNA regulatory elements which influence high level gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

DNA binding and regulatory effects of transcription factors SP1 and USF at the rat amyloid precursor protein gene promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Binding and selective detection of the secretory N-terminal domain of the alzheimer amyloid precursor protein on cell surfaces

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

The kunitz protease inhibitor form of the amyloid precursor protein (KPI/APP) inhibits the proneuropeptide processing enzyme prohormone thiol protease (PTP). Colocalization of KPI/APP and PTP in secretory vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Modulation of secreted beta-amyloid precursor protein and amyloid beta-peptide in brain by cholesterol.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

cDNA cloning and molecular characterization of human brain metalloprotease MP100: a beta-secretase candidate?

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Increased expression of beta-amyloid precursor protein during neuronal differentiation is not accompanied by secretory cleavage

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

The presenilins and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Nonisotopic in situ hybridization of amyloid beta protein precursor in Alzheimer's disease: expression in neurofibrillary tangle bearing neurons and in the microenvironment surrounding senile plaques.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Analysis of heterogeneous A4 peptides in human cerebrospinal fluid and blood by a newly developed sensitive Western blot assay.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Enhanced localization of amyloid beta precursor protein in the rat hippocampus following long-term adrenalectomy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Altered processing of Alzheimer amyloid precursor protein in response to neuronal degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Positive and negative regulatory elements for the expression of the Alzheimer's disease amyloid precursor-encoding gene in mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Beta-amyloid (1-42) peptide impairs blood-brain barrier function after intracarotid infusion in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Selective reduction of mRNA for the beta-amyloid precursor protein that lacks a Kunitz-type protease inhibitor motif in cortex from Alzheimer brains

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Relation of neuronal APP-751/APP-695 mRNA ratio and neuritic plaque density in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Neuronal beta-amyloid precursor protein gene expression: regulation by aurintricarboxylic acid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Differential splicing of Alzheimer's disease amyloid A4 precursor RNA in rat tissues: PreA4(695) mRNA is predominantly produced in rat and human brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Expression of APP in the early stage of brain damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Amyloid beta protein precursor accumulates in swollen neurites throughout rat brain with aging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Amyloid beta-peptide disrupts carbachol-induced muscarinic cholinergic signal transduction in cortical neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Beta A4(25-35) modulates substance P effect on rat skin microvasculature in aged rats: pharmacological manipulation using SEC-receptor ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Mechanisms underlying the vascular activity of beta-amyloid protein fragment (beta A(4)25-35) at the level of skin microvasculature

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

beta-Amyloid precursor protein binds to the neurite-promoting IKVAV site of laminin

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Selective localization of amyloid precursor-like protein 1 in the cerebral cortex postsynaptic density

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Amyloid beta-protein activates tachykinin receptors and inositol trisphosphate accumulation by synergy with glutamate

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Activation of macrophages by Alzheimer beta amyloid peptide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Amyloid beta-protein precursor is associated with extracellular matrix

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Cell surface APP751 forms complexes with protease nexin 2 ligands and is internalized via the low density lipoprotein receptor-related protein (LRP).

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Beta-amyloid protein increases the vulnerability of cultured cortical neurons to excitotoxic damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Involvement of cell surface glycosyl-phosphatidylinositol-linked aspartyl proteases in alpha-secretase-type cleavage and ectodomain solubilization of human Alzheimer beta-amyloid precursor protein in yeast.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Alternative splicing of the βA4 amyloid gene of Alzheimer's disease in cortex of control and Alzheimer's disease patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Precursor of amyloid protein in Alzheimer disease undergoes fast anterograde axonal transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Widespread axonal injury in gunshot wounds to the head using amyloid precursor protein as a marker.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

The deletion of the C-terminal tail and addition of an endoplasmic reticulum targeting signal to Alzheimer's amyloid precursor protein change its localization, secretion, and intracellular proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Proteasome inhibitors induce the association of Alzheimer's amyloid precursor protein with Hsc73.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

An in vivo model for the neurodegenerative effects of beta amyloid and protection by substance P

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

The promoter activity of the gene encoding Alzheimer β-amyloid precursor protein (APP) is regulated by two blocks of upstream sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Altered metabolism of familial Alzheimer's disease-linked amyloid precursor protein variants in yeast artificial chromosome transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Beta/A4-evoked degeneration of differentiated SH-SY5Y human neuroblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Chronic elevation of amyloid precursor protein expression in the neocortex and hippocampus of rats with selective cholinergic lesions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Amyloid precursor protein gene expression in neural cell lines: influence of DNA cytosine methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

A detergent-insoluble membrane compartment contains A beta in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Gelatinase A possesses a beta-secretase-like activity in cleaving the amyloid protein precursor of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Thioflavine T interaction with synthetic Alzheimer's disease beta-amyloid peptides: detection of amyloid aggregation in solution

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Stopped-flow kinetics reveal multiple phases of thioflavin T binding to Alzheimer beta (1-40) amyloid fibrils.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Mutation of the Alzheimer's disease amyloid gene in hereditary cerebral hemorrhage, Dutch type.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

A familial Alzheimer's disease locus on chromosome 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Beta-amyloid induces apoptosis in human-derived neurotypic SH-SY5Y cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Zyme, a novel and potentially amyloidogenic enzyme cDNA isolated from Alzheimer's disease brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Apoptosis is induced by beta-amyloid in cultured central nervous system neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Rational design of an animal model for Alzheimer's disease: introduction of multiple human genomic transgenes to reproduce AD pathology in a rodent

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Protein-DNA interactions in the promoter region of the amyloid precursor protein (APP) gene in human neocortex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Human amyloid precursor protein ameliorates behavioral deficit of flies deleted for Appl gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

A possible role for cathepsins D, E, and B in the processing of beta-amyloid precursor protein in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

The long term adenoviral expression of the human amyloid precursor protein shows different secretase activities in rat cortical neurons and astrocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Membrane surface ruffling in cells that over-express Alzheimer amyloid beta/A4 C-terminal peptide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Amyloid beta protein (Abeta) deposition in chromosome 14-linked Alzheimer's disease: predominance of Abeta42(43).

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Lack of beta-amyloid production in M19 cells deficient in site 2 processing of the sterol regulatory element binding proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Aluminum, iron, and zinc ions promote aggregation of physiological concentrations of beta-amyloid peptide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Neuronal nicotinic receptor deficits in Alzheimer patients with the Swedish amyloid precursor protein 670/671 mutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

"Secretase," Alzheimer amyloid protein precursor secreting enzyme is not sequence-specific

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Cleavage at the N-terminal site of Alzheimer amyloid beta/A4 protein is essential for its secretion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Amyloid plaque core protein in Alzheimer disease and Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Familial Alzheimer's disease cells abnormally accumulate beta-amyloid-harbouring peptides preferentially in cytosol but not in extracellular fluid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the beta-amyloid precursor protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

The processing of Alzheimer A4/beta-amyloid protein precursor: identification of a human brain metallopeptidase which cleaves -Lys-Leu- in a model peptide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Immunohistochemical and in situ analysis of amyloid precursor-like protein-1 and amyloid precursor-like protein-2 expression in Alzheimer disease and aged control brains

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Activation of microglial cells by beta-amyloid protein and interferon-gamma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Increased Abeta42(43) from cell lines expressing presenilin 1 mutations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

The effects of beta/A4-amyloid and its fragments on calcium homeostasis, glial fibrillary acidic protein and S100beta staining, morphology and survival of cultured hippocampal astrocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Memory-enhancing effects of secreted forms of the beta-amyloid precursor protein in normal and amnestic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

The amyloid protein precursor of Alzheimer's disease is a mediator of the effects of nerve growth factor on neurite outgrowth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Amyloid β protein substituent peptides do not interact with the substance P receptor expressed in cultured cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

A metalloproteinase inhibitor domain in Alzheimer amyloid protein precursor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Transgenic mice expressing an alpha-secretion mutant of the amyloid precursor protein in the brain develop a progressive CNS disorder.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Relative increase in Alzheimer's disease of soluble forms of cerebral Abeta amyloid protein precursor containing the Kunitz protease inhibitory domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Inhibition of Protease Activity Can Lead to Neurite Extension in Neuroblastoma Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Extracellular matrix influences the biogenesis of amyloid precursor protein in microglial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Nicotine effects on the regulation of amyloid precursor protein splicing, neurotrophin and glucose transporter RNA levels in aged rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Neurotrophic and neuroprotective effects of hAPP in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of beta-amyloid

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Behavioral and anatomical deficits in mice homozygous for a modified beta-amyloid precursor protein gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Mice homozygous for a modified beta-amyloid precursor protein (beta APP) gene show impaired behavior and high incidence of agenesis of the corpus callosum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Lu 25-109, a combined m1 agonist and m2 antagonist, modulates regulated processing of the amyloid precursor protein of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Experimental brain injury induces expression of amyloid precursor protein, which may be related to neuronal loss in the hippocampus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

A mutation in the amyloid precursor protein associated with hereditary Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Kainic acid: Neurophysiological and neurotoxic actions

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Amyloid beta-protein precursor deposition in rat hippocampus lesioned by ibotenic acid injection

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Accumulation of amyloid beta-protein precursor (APP) in Purkinje cells and increase of amino-terminal fragments of APP in cerebrum and cerebellum of aged rat brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Effect of aluminium on expression and processing of amyloid precursor protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Expression of the Alzheimer amyloid precursor gene transcripts in the human brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

The Alzheimer amyloid precursor-related transcript lacking the beta/A4 sequence is specifically increased in Alzheimer's disease brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Brain transplants of cells expressing the carboxyl-terminal fragment of the Alzheimer amyloid protein precursor cause specific neuropathology in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Apolipoprotein E epsilon 4 allele is associated with deposition of amyloid beta-protein following head injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Alzheimer amyloid protein precursor complexes with brain GTP-binding protein G(o)

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Release of amyloid beta-protein precursor derivatives by electrical depolarization of rat hippocampal slices

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Serotonin 5-HT2a and 5-HT2c receptors stimulate amyloid precursor protein ectodomain secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

The rat central nervous system expresses Alzheimer's amyloid precursor protein APP695, but not APP677 (L-APP form).

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Developmental and differential expression of beta amyloid protein precursor mRNAs in mouse brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

The secreted form of the Alzheimer's amyloid precursor protein with the Kunitz domain is protease nexin-II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Rapid appearance of beta-amyloid precursor protein immunoreactivity in damaged axons and reactive glial cells in rat brain following needle stab injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Human and rodent Alzheimer beta-amyloid peptides acquire distinct conformations in membrane-mimicking solvents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Self-oligomerization of NACP, the precursor protein of the non-amyloid beta/A4 protein (A beta) component of Alzheimer's disease amyloid, observed in the presence of a C-terminal A beta fragment (residues 25-35).

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Lymphocyte content of amyloid precursor protein is increased in Down's syndrome and aging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

The beta-amyloid protein precursor of Alzheimer disease has soluble derivatives found in human brain and cerebrospinal fluid

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Altered levels and splicing of the amyloid precursor protein in the adult rat hippocampus after treatment with DMSO or retinoic acid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

The amyloid precursor protein gene: a neuropeptide gene with diverse functions in the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

The effects of excitotoxicity on the expression of the amyloid precursor protein gene in the brain and its modulation by neuroprotective agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Amyloid precursor protein gene isoforms in Alzheimer's disease and other neurodegenerative disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

The chondroitin sulfate attachment site of appican is formed by splicing out exon 15 of the amyloid precursor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Characterization of appican, the chondroitin sulfate proteoglycan form of the Alzheimer amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Beta-amyloid-induced changes in cultured astrocytes parallel reactive astrocytosis associated with senile plaques in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Calretinin-immunoreactive neurons are resistant to beta-amyloid toxicity in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Effect of propentofylline on hippocampal brain energy state and amyloid precursor protein concentration in a rat model of cerebral hypoperfusion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

The expression of the amyloid precursor protein (APP) is regulated by two GC-elements in the promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Effects of the amyloid protein precursor of Alzheimer's disease and other ligands of the LDL receptor-related protein on neurite outgrowth from sympathetic neurons in culture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Beta APP mRNA transcription is increased in cultured fibroblasts from the familial Alzheimer's disease-1 family.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Formation of beta-amyloid protein deposits in brains of transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Amyloid precursor protein metabolism in fibroblasts from individuals with one, two or three copies of the amyloid precursor protein (APP) gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Somatic mutation analysis of the APP and Presenilin 1 and 2 genes in Alzheimer's disease brains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Strategies for the design of minor groove binders: a re-evaluation based on the emergence of site-selective carbohydrate binders

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Cyclic nucleotide crosstalk and the regulation of cerebral vasodilation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Characterization of proteases with the specificity to cleave at the secretase-site of beta-APP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

The regulation of amyloid beta protein precursor secretion and its modulatory role in cell adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

The expression of amyloid beta protein precursor protects nerve cells from beta-amyloid and glutamate toxicity and alters their interaction with the extracellular matrix

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Amyloid peptides are toxic via a common oxidative mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Localization of Alzheimer beta A4 amyloid precursor protein at central and peripheral synaptic sites.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Rat brain glyceraldehyde-3-phosphate dehydrogenase interacts with the recombinant cytoplasmic domain of Alzheimer's beta-amyloid precursor protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Transthyretin sequesters amyloid beta protein and prevents amyloid formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

β-Amyloid precursor protein gene is differentially expressed in axotomized sensory and motor systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Beta-amyloid precursor protein of Alzheimer disease occurs as 110- to 135-kilodalton membrane-associated proteins in neural and nonneural tissues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Isolation and quantification of soluble Alzheimer's beta-peptide from biological fluids

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Secretion of beta-amyloid precursor protein cleaved at the amino terminus of the beta-amyloid peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Expressing mRNAs for presenilin-1 and amyloid precursor protein (APP-695) from same neuronal populations in rat hippocampus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Regulated splicing of the amyloid precursor protein gene during postnatal development of the rat basal forebrain

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Estrogen attenuates over-expression of beta-amyloid precursor protein messager RNA in an animal model of focal ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Reactive microglia/macrophages phagocytose amyloid precursor protein produced by neurons following neural damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Receptor-mediated specific biological activity of a beta-amyloid protein fragment for NK-1 substance P receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Activation of microglial cells by PrP and beta-amyloid fragments raises intracellular calcium through L-type voltage sensitive calcium channels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Two-dimensional gel mapping of the processing of the human amyloid precursor protein in rat hippocampal neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Activation of LA-N-2 cell phospholipase D by amyloid beta protein (25-35).

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Evidence that beta-amyloid protein in Alzheimer's disease is not derived by normal processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Beta-amyloid precursor protein cleavage by a membrane-bound protease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

A protease activity associated with acetylcholinesterase releases the membrane-bound form of the amyloid protein precursor of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Nerve growth factor-induced neuronal differentiation is accompanied by differential splicing of beta-amyloid precursor mRNAs in the PC12 cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

NGF deprivation and neuronal degeneration trigger altered beta-amyloid precursor protein gene expression in the rat superior cervical ganglia in vivo and in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Increased levels of the Kunitz protease inhibitor-containing beta APP mRNAs in rat brain following neurotoxic damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Differential regional and cellular distribution of beta-amyloid precursor protein messenger RNAs containing and lacking the Kunitz protease inhibitor domain in the brain of human, rat and mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Intraneuronal beta-amyloid immunoreactivity in the CNS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Molecular cloning of the cDNA for a human amyloid precursor protein homolog: evidence for a multigene family

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Amyloid precursor protein accumulates in regions of neurodegeneration following focal cerebral ischemia in the rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Beta-amyloid peptide 25-35 regulates basal and hormone-stimulated Ca2+ levels in cultured rat astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

The low density lipoprotein receptor gene family. Differential expression of two alpha2-macroglobulin receptors in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Intravascular infusions of soluble beta-amyloid compromise the blood-brain barrier, activate CNS glial cells and induce peripheral hemorrhage

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Molecular physiology, biochemistry, and pharmacology of Alzheimer's amyloid precursor protein (APP).

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Intrahippocampal injections of exogenous beta-amyloid induce postdelay errors in an eight-arm radial maze.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Alzheimer's disease amyloid beta-clipping enzyme (APP secretase): identification, purification, and characterization of the enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Tau protein kinase I is essential for amyloid beta-protein-induced neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

X11L2, a new member of the X11 protein family, interacts with Alzheimer's beta-amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Reaction of astrocytes in the gerbil hippocampus following transient ischemia: immunohistochemical observations with antibodies against glial fibrillary acidic protein, glutamine synthetase, and S-100 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Amyloid beta protein gene: cDNA, mRNA distribution, and genetic linkage near the Alzheimer locus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Cellular specificity and regional distribution of amyloid beta protein precursor alternative transcripts are unaltered in Alzheimer hippocampal formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Disruption of circadian regulation by brain grafts that overexpress Alzheimer beta/A4 amyloid

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Metabolism of the "Swedish" amyloid precursor protein variant in neuro2a (N2a) cells. Evidence that cleavage at the "beta-secretase" site occurs in the golgi apparatus

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Temporal profiles of accumulation of amyloid beta/A4 protein precursor in the gerbil after graded ischemic stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Interaction of a neuron-specific protein containing PDZ domains with Alzheimer's amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Interaction of cytosolic adaptor proteins with neuronal apolipoprotein E receptors and the amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

The triplet of lysine residues (Lys724-Lys725-Lys726) of Alzheimer's amyloid precursor protein plays an important role in membrane anchorage and processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Frameshift mutants of beta amyloid precursor protein and ubiquitin-B in Alzheimer's and Down patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Protease nexin-II, a potent antichymotrypsin, shows identity to amyloid beta-protein precursor

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Characterization of beta-amyloid peptide from human cerebrospinal fluid

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Generation of APLP2 KO mice and early postnatal lethality in APLP2/APP double KO mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Regional accumulation of amyloid beta/A4 protein precursor in the gerbil brain following transient cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Amyloid precursor protein in the cerebral cortex is rapidly and persistently induced by loss of subcortical innervation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Do c-Jun, c-Fos, and amyloid precursor protein play a role in neuronal death or survival?

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Identification of a mouse brain cDNA that encodes a protein related to the Alzheimer disease-associated amyloid beta protein precursor

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Isolation and characterization of APLP2 encoding a homologue of the Alzheimer's associated amyloid beta protein precursor

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

A 127-kDa protein (UV-DDB) binds to the cytoplasmic domain of the Alzheimer's amyloid precursor protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Postmortem brains reveal similar but not identical amyloid precursor protein-like immunoreactivity in Alzheimer compared with other dementias.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Formation of stable complexes between two Alzheimer's disease gene products: presenilin-2 and beta-amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Proteolytic processing of the Alzheimer's disease amyloid precursor protein within its cytoplasmic domain by caspase-like proteases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Amyloid precursor protein mRNA encoding the Kunitz protease inhibitor domain is increased by kainic acid-induced seizures in rat hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Peptides homologous to the amyloid protein of Alzheimer's disease containing a glutamine for glutamic acid substitution have accelerated amyloid fibril formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Interaction between amyloid precursor protein and presenilins in mammalian cells: implications for the pathogenesis of Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Presenilin 1 regulates the processing of beta-amyloid precursor protein C-terminal fragments and the generation of amyloid beta-protein in endoplasmic reticulum and Golgi.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Regulated formation of Golgi secretory vesicles containing Alzheimer beta-amyloid precursor protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Generation of Alzheimer beta-amyloid protein in the trans-Golgi network in the apparent absence of vesicle formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Estrogen reduces neuronal generation of Alzheimer beta-amyloid peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Neuron-specific splicing of the Alzheimer amyloid precursor protein gene in a mini-gene system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

An intracellular protein that binds amyloid-beta peptide and mediates neurotoxicity in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

IL-1 beta decreases expression of amyloid precursor protein gene in human glioma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

The chaperone BiP/GRP78 binds to amyloid precursor protein and decreases Abeta40 and Abeta42 secretion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Degeneration in vitro of post-mitotic neurons overexpressing the Alzheimer amyloid protein precursor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

NACP, the precursor protein of the non-amyloid beta/A4 protein (A beta) component of Alzheimer disease amyloid, binds A beta and stimulates A beta aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

The biosynthesis of cyclopropanated mycolic acids in Mycobacterium tuberculosis. Identification and functional analysis of CMAS-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

beta-Amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Mice deficient for the amyloid precursor protein gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

PAT1, a microtubule-interacting protein, recognizes the basolateral sorting signal of amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Binding of vascular heparan sulfate proteoglycan to Alzheimer's amyloid precursor protein is mediated in part by the N-terminal region of A4 peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Amyloid beta protein precursor gene and hereditary cerebral hemorrhage with amyloidosis (Dutch)

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

Amyloid-associated proteins α1-antichymotrypsin and apolipoprotein E promote assembly of Alzheimer β-protein into filaments

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2001.12.1.1

10.1515/REVNEURO.2001.12.1.1

21 January 2018

Identifiers

DOI

1 reference

31 July 2017

1 reference

PubMed ID

11236063