Regulation of p70 S6 kinase by complex formation between the Rac guanine nucleotide exchange factor (Rac-GEF) Tiam1 and the scaffold spinophilin (Q34171088)

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English	Regulation of p70 S6 kinase by complex formation between the Rac guanine nucleotide exchange factor (Rac-GEF) Tiam1 and the scaffold spinophilin	scientific article

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scholarly article

1 reference

Europe PubMed Central

31 July 2017

Regulation of p70 S6 kinase by complex formation between the Rac guanine nucleotide exchange factor (Rac-GEF) Tiam1 and the scaffold spinophilin (English)

1 reference

Europe PubMed Central

31 July 2017

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author name string

Rachel J Buchsbaum

1

1 reference

Europe PubMed Central

31 July 2017

Beth A Connolly

2

1 reference

Europe PubMed Central

31 July 2017

Larry A Feig

3

1 reference

Europe PubMed Central

31 July 2017

language of work or name

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publication date

16 January 2003

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Europe PubMed Central

31 July 2017

Journal of Biological Chemistry

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Europe PubMed Central

31 July 2017

278

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Europe PubMed Central

31 July 2017

21

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Europe PubMed Central

31 July 2017

18833-18841

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Europe PubMed Central

31 July 2017

Rho, rac and cdc42 GTPases: regulators of actin structures, cell adhesion and motility

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207876200

21 January 2018

The Dbl family of oncogenes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207876200

21 January 2018

Identification of an invasion-inducing gene, Tiam-1, that encodes a protein with homology to GDP-GTP exchangers for Rho-like proteins.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207876200

21 January 2018

A role for Rac in Tiam1-induced membrane ruffling and invasion

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207876200

21 January 2018

Inhibition of invasion of epithelial cells by Tiam1-Rac signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207876200

21 January 2018

Tiam1 overexpression potentiates heregulin-induced lymphoid enhancer factor-1/beta -catenin nuclear signaling in breast cancer cells by modulating the intercellular stability

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207876200

21 January 2018

Rac affects invasion of human renal cell carcinomas by up-regulating tissue inhibitor of metalloproteinases (TIMP)-1 and TIMP-2 expression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207876200

21 January 2018

Mice deficient in the Rac activator Tiam1 are resistant to Ras-induced skin tumours.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207876200

21 January 2018

Ca2+/calmodulin-dependent protein kinase II regulates Tiam1 by reversible protein phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207876200

21 January 2018

Regulation of the Rac1-specific exchange factor Tiam1 involves both phosphoinositide 3-kinase-dependent and -independent components

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207876200

21 January 2018

Guanine nucleotide exchange factors regulate specificity of downstream signaling from Rac and Cdc42.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207876200

21 January 2018

PAK kinases are directly coupled to the PIX family of nucleotide exchange factors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207876200

21 January 2018

A novel regulator of p21-activated kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207876200

21 January 2018

Molecular cloning of neuronally expressed mouse betaPix isoforms

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207876200

21 January 2018

Targeting of Tiam1 to the plasma membrane requires the cooperative function of the N-terminal pleckstrin homology domain and an adjacent protein interaction domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207876200

21 January 2018

Regulated membrane localization of Tiam1, mediated by the NH2-terminal pleckstrin homology domain, is required for Rac-dependent membrane ruffling and C-Jun NH2-terminal kinase activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207876200

21 January 2018

The N-terminal pleckstrin, coiled-coil, and IQ domains of the exchange factor Ras-GRF act cooperatively to facilitate activation by calcium

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207876200

21 January 2018

Interaction of Rac exchange factors Tiam1 and Ras-GRF1 with a scaffold for the p38 mitogen-activated protein kinase cascade

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207876200

21 January 2018

Spinophilin, a novel protein phosphatase 1 binding protein localized to dendritic spines

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207876200

21 January 2018

Neurabin-II/spinophilin. An actin filament-binding protein with one pdz domain localized at cadherin-based cell-cell adhesion sites.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207876200

21 January 2018

Neurabin is a synaptic protein linking p70 S6 kinase and the neuronal cytoskeleton

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207876200

21 January 2018

Identification of a mouse p21Cdc42/Rac activated kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207876200

21 January 2018

The 70 kDa S6 kinase complexes with and is activated by the Rho family G proteins Cdc42 and Rac1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207876200

21 January 2018

Translocation of the Rac1 guanine nucleotide exchange factor Tiam1 induced by platelet-derived growth factor and lysophosphatidic acid

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207876200

21 January 2018

Signal transduction: hanging on a scaffold.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207876200

21 January 2018

Neurabin: a novel neural tissue-specific actin filament-binding protein involved in neurite formation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207876200

21 January 2018

Targeting protein phosphatase 1 (PP1) to the actin cytoskeleton: the neurabin I/PP1 complex regulates cell morphology

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207876200

21 January 2018

Association of the D2 dopamine receptor third cytoplasmic loop with spinophilin, a protein phosphatase-1-interacting protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207876200

21 January 2018

Agonist-regulated Interaction between alpha2-adrenergic receptors and spinophilin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207876200

21 January 2018

The human tumor suppressor arf interacts with spinophilin/neurabin II, a type 1 protein-phosphatase-binding protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207876200

21 January 2018

Direct interaction of the trans-Golgi network membrane protein, TGN38, with the F-actin binding protein, neurabin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207876200

21 January 2018

G protein beta gamma subunit-dependent Rac-guanine nucleotide exchange activity of Ras-GRF1/CDC25(Mm)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207876200

21 January 2018

Stimulation of Ras guanine nucleotide exchange activity of Ras-GRF1/CDC25(Mm) upon tyrosine phosphorylation by the Cdc42-regulated kinase ACK1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207876200

21 January 2018

Rho GTPases and their effector proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207876200

21 January 2018

Tiam1 is involved in the regulation of bufalin-induced apoptosis in human leukemia cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207876200

21 January 2018

In vivo dynamics of the F-actin-binding protein neurabin-II

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207876200

21 January 2018

The p70 S6 kinase integrates nutrient and growth signals to control translational capacity.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207876200

21 January 2018

Identifiers

10.1074/JBC.M207876200

1 reference

Europe PubMed Central

31 July 2017

1 reference

Europe PubMed Central

31 July 2017

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