Intraperitoneal injection of the pancreatic peptide amylin potently reduces behavioral impairment and brain amyloid pathology in murine models of Alzheimer's disease. (Q34167833)

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English	Intraperitoneal injection of the pancreatic peptide amylin potently reduces behavioral impairment and brain amyloid pathology in murine models of Alzheimer's disease.	scientific article

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10 March 2020

Intraperitoneal injection of the pancreatic peptide amylin potently reduces behavioral impairment and brain amyloid pathology in murine models of Alzheimer's disease (English)

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10 March 2020

Alzheimer's disease

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Robert A. Stern

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H Zhu

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X Wang

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M Wallack

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I Carreras

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A Dedeoglu

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J-Y Hur

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H Zheng

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H Li

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R Fine

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M Mwamburi

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X Sun

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N Kowall

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W Q Qiu

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11 March 2014

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10 March 2020

Molecular Psychiatry

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10 March 2020

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11 March 2014

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https://scigraph.springernature.com/pub.10.1038/mp.2014.17

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Amylin deposition in the brain: A second amyloid in Alzheimer disease?

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Amyloid β (Aβ) peptide directly activates amylin-3 receptor subtype by triggering multiple intracellular signaling pathways

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Enhanced amylin-mediated body weight loss in estradiol-deficient diet-induced obese rats

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The beta-secretase enzyme BACE in health and Alzheimer's disease: regulation, cell biology, function, and therapeutic potential

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Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

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Pramlintide, the synthetic analogue of amylin: physiology, pathophysiology, and effects on glycemic control, body weight, and selected biomarkers of vascular risk

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Human but not rat amylin shares neurotoxic properties with Abeta42 in long-term hippocampal and cortical cultures

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Amyloid-associated depression: a prodromal depression of Alzheimer disease?

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Oral administration of a potent and selective non-peptidic BACE-1 inhibitor decreases beta-cleavage of amyloid precursor protein and amyloid-beta production in vivo

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Amylin: localization, effects on cerebral arteries and on local cerebral blood flow in the cat.

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12 December 2020

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Amylin-induced relaxation of the perfused mesenteric arterial bed: meditation by calcitonin gene-related peptide receptors

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12 December 2020

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10.1038/MP.2014.17

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10 March 2020

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10 March 2020

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10 March 2020

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