Diversification of specificity after maturation of the antibody response to the HIV gp41 epitope ELDKWA. (Q34163633)

31 July 2017

Diversification of specificity after maturation of the antibody response to the HIV gp41 epitope ELDKWA. (English)

1 reference

31 July 2017

Henry N White

1

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author name string

Qing-Hai Meng

series ordinal

2

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PubMed ID

22348106

31 July 2017

language of work or name

English

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publication date

14 February 2012

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31 July 2017

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31 July 2017

7

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31 July 2017

2

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31 July 2017

e31555

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Creative Commons Attribution 4.0 International

31 July 2017

start time

14 February 2012

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Memory B cells, but not long-lived plasma cells, possess antigen specificities for viral escape mutants

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Very low affinity B cells form germinal centers, become memory B cells, and participate in secondary immune responses when higher affinity competition is reduced

5 July 2018

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The extent of affinity maturation differs between the memory and antibody-forming cell compartments in the primary immune response

5 July 2018

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In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. III. The kinetics of V region mutation and selection in germinal center B cells

5 July 2018

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Tracing B cell development in human germinal centres by molecular analysis of single cells picked from histological sections

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A conserved neutralizing epitope on gp41 of human immunodeficiency virus type 1

5 July 2018

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Cross-neutralizing activity against divergent human immunodeficiency virus type 1 isolates induced by the gp41 sequence ELDKWAS.

5 July 2018

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Neutralization of divergent human immunodeficiency virus type 1 variants and primary isolates by IAM-41-2F5, an anti-gp41 human monoclonal antibody

5 July 2018

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Single amino acid substitution altering antigen-binding specificity

5 July 2018

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5 July 2018

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Altered hapten recognition by two anti-digoxin hybridoma variants due to variable region point mutations.

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Different epitope structures select distinct mutant forms of an antibody variable region for expression during the immune response

5 July 2018

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Accumulation of somatic mutants in the B cell compartment after primary immunization with a T cell-dependent antigen

5 July 2018

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The role of somatic mutation in the generation of the protective humoral immune response against vesicular stomatitis virus.

5 July 2018

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CD95 (Fas)-dependent elimination of self-reactive B cells upon interaction with CD4+ T cells.

21 January 2018

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Soluble antigen can cause enhanced apoptosis of germinal-centre B cells.

21 January 2018

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In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. IV. Affinity-dependent, antigen-driven B cell apoptosis in germinal centers as a mechanism for maintaining self-tolerance

21 January 2018

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Structure-affinity relationships in the gp41 ELDKWA epitope for the HIV-1 neutralizing monoclonal antibody 2F5: effects of side-chain and backbone modifications and conformational constraints

21 January 2018

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In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. V. Affinity maturation develops in two stages of clonal selection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0031555

Degeneracy of antibody specificity

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22348106

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Role of BCR affinity in T cell dependent antibody responses in vivo

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22348106

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Guidelines for the production of polypeptide specific antisera using small synthetic oligopeptides as immunogens

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22348106

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0031555

1 reference

31 July 2017

0 references

1 reference

31 July 2017

1 reference

PubMed ID

22348106