Arachidonate 12-lipoxygenases (Q34159100)

31 July 2017

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title

Arachidonate 12-lipoxygenases. (English)

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31 July 2017

Tanihiro Yoshimoto

1

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PubMed ID

12432922

31 July 2017

Yoshitaka Takahashi

series ordinal

2

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31 July 2017

1 August 2002

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31 July 2017

18

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Prostaglandins and Other Lipid Mediators

inferred from page(s)

published in

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31 July 2017

68-69

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31 July 2017

245-262

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Prostaglandin endoperoxides. Novel transformations of arachidonic acid in human platelets

31 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Arachidonate lipoxygenase in blood platelets

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Lipoxygenases: occurrence, functions, catalysis, and acquisition of substrate

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Arachidonate 12-lipoxygenase

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Arachidonate 12-lipoxygenases

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

The molecular biology of mammalian lipoxygenases and the quest for eicosanoid functions using lipoxygenase-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

The diversity of the lipoxygenase family. Many sequence data but little information on biological significance

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

The arachidonate 12/15 lipoxygenases. A review of tissue expression and biologic function

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Cloning and sequence analysis of the cDNA for arachidonate 12-lipoxygenase of porcine leukocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Cloning and characterization of a murine macrophage lipoxygenase.

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Arachidonate 12-lipoxygenase of rat pineal glands: catalytic properties and primary structure deduced from its cDNA

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Molecular cloning of a 12-lipoxygenase cDNA from rat brain

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Simultaneous expression of leukocyte-type 12-lipoxygenase and reticulocyte-type 15-lipoxygenase in rabbits

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Molecular cloning, primary structure, and expression of the human platelet/erythroleukemia cell 12-lipoxygenase

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Cloning of the cDNA for human 12-lipoxygenase

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Molecular cloning and expression of human arachidonate 12-lipoxygenase

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Genomic and cDNA cloning of a novel mouse lipoxygenase gene

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Functional expression and cellular localization of a mouse epidermal lipoxygenase

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Murine epidermal lipoxygenase (Aloxe) encodes a 12-lipoxygenase isoform

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Disruption of 12/15-lipoxygenase expression in peritoneal macrophages. Enhanced utilization of the 5-lipoxygenase pathway and diminished oxidation of low density lipoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Cloning of a human "epidermal-type" 12-lipoxygenase-related gene and chromosomal localization to 17p13.

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

cDNA cloning, genomic structure, and chromosomal localization of a novel murine epidermis-type lipoxygenase

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

A gene cluster encoding human epidermis-type lipoxygenases at chromosome 17p13.1: cloning, physical mapping, and expression

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Expression of arachidonate 12-lipoxygenase in rat tissues: a possible role in glucagon secretion

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

cDNA cloning of 15-lipoxygenase type 2 and 12-lipoxygenases of bovine corneal epithelium.

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Trout thrombocytes contain 12- but not 5-lipoxygenase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Arachidonate 12-lipoxygenase in porcine anterior pituitary cells: its localization and possible function in gonadotrophs

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Diurnal change of arachidonate 12-lipoxygenase in rat pineal gland.

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Epidermis contains platelet-type 12-lipoxygenase that is overexpressed in germinal layer keratinocytes in psoriasis

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

An anti-platelet agent, OPC-29030, inhibits translocation of 12-lipoxygenase and 12-hydroxyeicosatetraenoic acid production in human platelets

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

The structure of mammalian 15-lipoxygenase reveals similarity to the lipases and the determinants of substrate specificity

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Site-directed mutagenesis studies on the iron-binding domain and the determinant for the substrate oxygenation site of porcine leukocyte arachidonate 12-lipoxygenase.

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Shape and specificity in mammalian 15-lipoxygenase active site. The functional interplay of sequence determinants for the reaction specificity.

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

A primary determinant for lipoxygenase positional specificity

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Rat 12-lipoxygenase: mutations of amino acids implicated in the positional specificity of 15- and 12-lipoxygenases

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Investigation of the oxygenation of phospholipids by the porcine leukocyte and human platelet arachidonate 12-lipoxygenases

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Selective oxygenation of the endocannabinoid 2-arachidonylglycerol by leukocyte-type 12-lipoxygenase

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Suicide inactivation of porcine leukocyte 12-lipoxygenase associated with its incorporation of 15-hydroperoxy-5,8,11,13-eicosatetraenoic acid derivative

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Inactivation of mouse epidermal 12-lipoxygenase by anthralin--implications for the role of oxygen radicals

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Identification of 12-lipoxygenase interaction with cellular proteins by yeast two-hybrid screening

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

12-hydroxyeicosatetraenoic acid is a long-lived substance in the rabbit circulation

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Langerhans cells of the human skin possess high-affinity 12(S)-hydroxyeicosa tetraenoic acid receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

A 12(S)-hydroxyeicosatetraenoic acid receptor interacts with steroid receptor coactivator-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Regulation of cyclooxygenase and 12-lipoxygenase catalysis by phospholipid hydroperoxide glutathione peroxidase in A431 cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Characterization of human 12-lipoxygenase genes

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

The transcriptional regulation of human arachidonate 12-lipoxygenase gene by NF kappa B/Rel

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Specific inflammatory cytokines regulate the expression of human monocyte 15-lipoxygenase

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Regulation of 12-lipoxygenase by cytokines in vascular smooth muscle cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Regulation of human 12/15-lipoxygenase by Stat6-dependent transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Interleukin-4-dependent production of PPAR-gamma ligands in macrophages by 12/15-lipoxygenase

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Interleukin-1 enhances pancreatic islet arachidonic acid 12-lipoxygenase product generation by increasing substrate availability through a nitric oxide-dependent mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

12-Lipoxygenase in A431 cells: genetic identity, modulation of expression, and intracellular localization

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Requirement for epidermal growth factor receptor tyrosine kinase and for 12-lipoxygenase activity in the expression of 12-lipoxygenase in human epidermoid carcinoma cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Epidermal growth factor enhances transcription of human arachidonate 12-lipoxygenase in A431 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Transcriptional activation of human 12-lipoxygenase gene promoter is mediated through Sp1 consensus sites in A431 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Overexpression of c-Fos enhances the transcription of human arachidonate 12-lipoxygenase in A431 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Overexpression of Ha-ras enhances the transcription of human arachidonate 12-lipoxygenase promoter in A431 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Functional interaction between c-Jun and promoter factor Sp1 in epidermal growth factor-induced gene expression of human 12(S)-lipoxygenase

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Induction of 12-lipoxygenase expression by transforming growth factor-alpha in human epidermoid carcinoma A431 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Induction of 12-lipoxygenase expression by phorbol 12-myristate 13-acetate in human epidermoid carcinoma A431 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

In vivo stimulation of 12(S)-lipoxygenase in the rat skin by bradykinin and platelet activating factor: formation of 12(S)-HETE and hepoxilins, and actions on vascular permeability

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Mechanisms of ANG II-induced mitogenic responses: role of 12-lipoxygenase and biphasic MAP kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Lipoxygenase metabolites of arachidonic acid as second messengers for presynaptic inhibition of Aplysia sensory cells

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Formation and action of 8-hydroxy-11,12-epoxy-5,9,14-icosatrienoic acid in Aplysia: a possible second messenger in neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Direct modulation of Aplysia S-K+ channels by a 12-lipoxygenase metabolite of arachidonic acid.

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Roles of arachidonic acid, lipoxygenases and phosphatases in calcium-dependent modulation of M-current in bullfrog sympathetic neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

How opioids inhibit GABA-mediated neurotransmission.

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Angiotensin II increases neuronal delayed rectifier K(+) current: role of 12-lipoxygenase metabolites of arachidonic acid

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Modulation of Synapse Formation by Cyclic Adenosine Monophosphate

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Two polyphosphatidylinositide metabolites control two K+ currents in a neuronal cell

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

12-Lipoxygenase overexpression in rodent NG108-15 cells enhances membrane excitability by inhibiting M-type K+ channels

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

M-currents: an update

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Localization of arachidonate 12-lipoxygenase in canine brain tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

KCNQ2 and KCNQ3 potassium channel subunits: molecular correlates of the M-channel

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Moderate loss of function of cyclic-AMP-modulated KCNQ2/KCNQ3 K+ channels causes epilepsy

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Phenidone blocks the increases of proenkephalin and prodynorphin gene expression induced by kainic acid in rat hippocampus: involvement of Fos-related antigene protein.

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

The cyclooxygenase and lipoxygenase inhibitor BW755C protects rats against kainic acid-induced seizures and neurotoxicity.

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Involvement of the 12-lipoxygenase pathway of arachidonic acid metabolism in homosynaptic long-term depression of the rat hippocampus.

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

12-Lipoxygenase Products Attenuate the Glutamate Release and Ca2+Accumulation Evoked by Depolarization of Hippocampal Mossy Fiber Nerve Endings

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Modulation of glutamate release from hippocampal mossy fiber nerve endings by arachidonic acid and eicosanoids

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Deficiency of platelet lipoxygenase activity in myeloproliferative disorders

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Decreased messenger RNA of arachidonate 12-lipoxygenase in platelets of patients with myeloproliferative disorders

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Increased platelet sensitivity to ADP in mice lacking platelet-type 12-lipoxygenase

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Disruption of the 12/15-lipoxygenase gene diminishes atherosclerosis in apo E-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Macrophage-mediated 15-lipoxygenase expression protects against atherosclerosis development

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Essential involvement of 12-lipoxygenase in regiospecific andstereospecific oxidation of low density lipoprotein by macrophages

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Structures and functions of multiligand lipoprotein receptors: macrophage scavenger receptors and LDL receptor-related protein (LRP).

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Expression of LDL receptor, VLDL receptor, LDL receptor-related protein, and scavenger receptor in rabbit atherosclerotic lesions: marked induction of scavenger receptor and VLDL receptor expression during lesion development

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Overexpression of 15-lipoxygenase in vascular endothelium accelerates early atherosclerosis in LDL receptor-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Low density lipoprotein receptor-related protein is required for macrophage-mediated oxidation of low density lipoprotein by 12/15-lipoxygenase

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Hepoxilins raise circulating insulin levels in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Resistance to type 1 diabetes induction in 12-lipoxygenase knockout mice

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Decreased activity of arachidonate 12-lipoxygenase in platelets of Japanese patients with non-insulin-dependent diabetes mellitus.

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Epoxyeicosatrienoic acids stimulate glucagon and insulin release from isolated rat pancreatic islets

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Elevated 12-lipoxygenase mRNA expression correlates with advanced stage and poor differentiation of human prostate cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Expression, subcellular localization and putative function of platelet-type 12-lipoxygenase in human prostate cancer cell lines of different metastatic potential

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

The 12-lipoxygenase gene-transfected MCF-7 human breast cancer cell line exhibits estrogen-independent, but estrogen and omega-6 fatty acid-stimulated proliferation in vitro, and enhanced growth in athymic nude mice

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Enhanced angiogenesis and growth of 12-lipoxygenase gene-transfected MCF-7 human breast cancer cells in athymic nude mice

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Metabolic suppression of platelet-type 12-lipoxygenase in human uterine cervix with invasive carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Arachidonate lipoxygenases as essential regulators of cell survival and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Apoptosis of W256 carcinosarcoma cells of the monocytoid origin induced by NDGA involves lipid peroxidation and depletion of GSH: role of 12-lipoxygenase in regulating tumor cell survival

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

12-Lipoxygenase inhibition induced apoptosis in human gastric cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Regulation of 12-lipoxygenase in rat intestinal epithelial cells during differentiation and apoptosis induced by sodium butyrate

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

A role for 12-lipoxygenase in nerve cell death caused by glutathione depletion.

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Platelet lipoxygenase in spontaneously hypertensive rats

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Increased levels of 12(S)-HETE in patients with essential hypertension

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Eicosanoids in sickle cell disease: potential relevance of 12(S)-hydroxy-5,8,10,14-eicosatetraenoic acid to the pathophysiology of vaso-occlusion

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Evidence for 12-lipoxygenase induction in the vessel wall following balloon injury.

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Expression of arachidonate platelet-type 12-lipoxygenase in human rheumatoid arthritis type B synoviocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

Collagenase-3 induction in rat lung fibroblasts requires the combined effects of tumor necrosis factor-alpha and 12-lipoxygenase metabolites: a model of macrophage-induced, fibroblast-driven extracellular matrix remodeling during inflammatory lung i

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2802%2900034-5

7 January 2021

10.1016/S0090-6980(02)00034-5

Identifiers

DOI

1 reference

31 July 2017

1 reference

PubMed ID

12432922