Synthetic small inhibiting RNAs: efficient tools to inactivate oncogenic mutations and restore p53 pathways. (Q34156507)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12403821%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

title

Synthetic small inhibiting RNAs: efficient tools to inactivate oncogenic mutations and restore p53 pathways (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12403821%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

5

1 reference

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14 December 2019

Annick Harel-Bellan

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12403821%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

author name string

Luis Alfonso Martinez

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12403821%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

Irina Naguibneva

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12403821%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

Heike Lehrmann

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12403821%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

Arlette Vervisch

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12403821%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

Guillermina Lozano

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12403821%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

language of work or name

English

0 references

publication date

28 October 2002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12403821%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

number of pages

6

1 reference

Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12403821%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

volume

99

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12403821%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

page(s)

14849-14854

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12403821%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

issue

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12403821%20AND%20SRC:MED&resulttype=core&format=json

siRNA-directed inhibition of HIV-1 infection

14 December 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137507

Activation of the p53 tumor suppressor protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137507

Therapeutic exploitation of the p53 pathway

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137507

A system for stable expression of short interfering RNAs in mammalian cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137507

Isoform-specific knockdown and expression of adaptor protein ShcA using small interfering RNA.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137507

Rescuing the function of mutant p53.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137507

Identification of essential genes in cultured mammalian cells using small interfering RNAs.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137507

Multiple roles of the tumor suppressor p53.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137507

The human papillomavirus E6 protein and its contribution to malignant progression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137507

Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137507

On the role of RNA amplification in dsRNA-triggered gene silencing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137507

A short primer on RNAi: RNA-directed RNA polymerase acts as a key catalyst

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137507

Tsg101 and the vacuolar protein sorting pathway are essential for HIV-1 budding

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137507

Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137507

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137507

5 July 2018

RNA interference--2001.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137507

Role for a bidentate ribonuclease in the initiation step of RNA interference

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137507

Transcriptional gene silencing in plants: targets, inducers and regulators

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137507

RNA interference is mediated by 21- and 22-nucleotide RNAs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137507

Oncogenic mutations of the p53 tumor suppressor: the demons of the guardian of the genome.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137507

5 July 2018

Surfing the p53 network

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137507

A common polymorphism acts as an intragenic modifier of mutant p53 behaviour

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137507

p73 and p63 are homotetramers capable of weak heterotypic interactions with each other but not with p53

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137507

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137507

p73 function is inhibited by tumor-derived p53 mutants in mammalian cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137507

p53, the cellular gatekeeper for growth and division

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137507

WAF1, a potential mediator of p53 tumor suppression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137507

Gain of function mutations in p53.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137507

Cyclin E restores p53 activity in contact-inhibited cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137507

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137507

p21 is necessary for the p53-mediated G1 arrest in human cancer cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137507

Spontaneous abnormalities in normal fibroblasts from patients with Li-Fraumeni cancer syndrome: aneuploidy and immortalization

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137507

Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137507

Oncogenic forms of p53 inhibit p53-regulated gene expression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137507

RNAi as random degradative PCR: siRNA primers convert mRNA into dsRNAs that are degraded to generate new siRNAs.

5 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.222406899

Erratum: Biochemical networking contributes more to genetic buffering in human and mouse metabolic pathways than does gene duplication

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.222406899

Physical and Functional Interaction between p53 Mutants and Different Isoforms of p73

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.222406899

A mutant p53 transgene accelerates tumour development in heterozygous but not nullizygous p53-deficient mice

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12403821

12 December 2020

inferred from PubMed ID database lookup

Specific P53 mutations are associated with de novo resistance to doxorubicin in breast cancer patients

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12403821

12 December 2020

inferred from PubMed ID database lookup

Tumour associated mutants of p53 can inhibit transcriptional activity of p53 without heterooligomerization

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12403821

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1073/PNAS.222406899

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12403821%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12403821%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

1 reference