Recent advances in the TR2 and TR4 orphan receptors of the nuclear receptor superfamily (Q34152879)

31 July 2017

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title

Recent advances in the TR2 and TR4 orphan receptors of the nuclear receptor superfamily (English)

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31 July 2017

Yi-Fen Lee

1

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PubMed ID

12361719

31 July 2017

Han-Jung Lee

series ordinal

2

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PubMed ID

12361719

31 July 2017

Chawnshang Chang

series ordinal

3

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31 July 2017

1 August 2002

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The Journal of Steroid Biochemistry and Molecular Biology

31 July 2017

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31 July 2017

81

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31 July 2017

4-5

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31 July 2017

291-308

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Steroid receptor family: structure and functions

31 July 2017

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

The steroid and thyroid hormone receptor superfamily

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

The RXR heterodimers and orphan receptors

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

The nuclear receptor superfamily: the second decade

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Molecular mechanisms of action of steroid/thyroid receptor superfamily members

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Molecular pathways of steroid receptor action

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Identification of a new class of steroid hormone receptors

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Evolution of the nuclear receptor superfamily: early diversification from an ancestral orphan receptor

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Determinants of target gene specificity for steroid/thyroid hormone receptors

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Two amino acids within the knuckle of the first zinc finger specify DNA response element activation by the glucocorticoid receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Three amino acids of the oestrogen receptor are essential to its ability to distinguish an oestrogen from a glucocorticoid-responsive element

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Differential orientations of the DNA-binding domain and carboxy-terminal dimerization interface regulate binding site selection by nuclear receptor heterodimers.

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Identification of the DNA binding site for NGFI-B by genetic selection in yeast

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Participation of non-zinc finger residues in DNA binding by two nuclear orphan receptors

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

The orientation and spacing of core DNA-binding motifs dictate selective transcriptional responses to three nuclear receptors

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Structural determinants of nuclear receptor assembly on DNA direct repeats

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

The dimerization interfaces formed between the DNA binding domains of RXR, RAR and TR determine the binding specificity and polarity of the full-length receptors to direct repeats.

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

The conserved ninth C-terminal heptad in thyroid hormone and retinoic acid receptors mediates diverse responses by affecting heterodimer but not homodimer formation

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

A domain containing leucine-zipper-like motifs mediate novel in vivo interactions between the thyroid hormone and retinoic acid receptors

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Two distinct dimerization interfaces differentially modulate target gene specificity of nuclear hormone receptors

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

The ligand-binding domains of the thyroid hormone/retinoid receptor gene subfamily function in vivo to mediate heterodimerization, gene silencing, and transactivation

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Unique response pathways are established by allosteric interactions among nuclear hormone receptors

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Synergistic activation of retinoic acid (RA)-responsive genes and induction of embryonal carcinoma cell differentiation by an RA receptor alpha (RAR alpha)-, RAR beta-, or RAR gamma-selective ligand in combination with a retinoid X receptor-specific

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Homodimer formation of retinoid X receptor induced by 9-cis retinoic acid

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Nuclear receptor coactivators and corepressors

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Nuclear receptors: coactivators, corepressors and chromatin remodeling in the control of transcription

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Nuclear matrix and the regulation of gene expression: tissue specificity

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Review: chromatin structural features and targets that regulate transcription

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Identification of a new member of the steroid receptor super-family by cloning and sequence analysis

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Molecular cloning of new human TR2 receptors: a class of steroid receptor with multiple ligand-binding domains

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Gene expression of the androgen repressed rat TR2 orphan receptor: a member of steroid receptor superfamily

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

A unified nomenclature system for the nuclear receptor superfamily

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

A bidirectional regulation between the TR2/TR4 orphan receptors (TR2/TR4) and the ciliary neurotrophic factor (CNTF) signaling pathway

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Distinct expression patterns and biological activities of two isoforms of the mouse orphan receptor TR2

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Isolation, regulation, and DNA-binding properties of three Drosophila nuclear hormone receptor superfamily members

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Cloning and characterization of new orphan nuclear receptors and their developmental profiles during Tenebrio metamorphosis

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Identification and characterization of a Drosophila nuclear receptor with the ability to inhibit the ecdysone response

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

A novel sea urchin nuclear receptor encoded by alternatively spliced maternal RNAs

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Molecular cloning from neurulating Ambystoma mexicanum embryos of the cDNA encoding an orphan nuclear receptor (aDOR1) closely related to TR2-11.

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Cloning of a cDNA for xDOR2, a novel TR2-related nuclear orphan receptor, expressed during neurulation in Xenopus laevis embryos.

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Cloning and characterization of two nuclear receptors from the filarial nematode Brugia pahangi

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Human and rat TR4 orphan receptors specify a subclass of the steroid receptor superfamily

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

TAK1: molecular cloning and characterization of a new member of the nuclear receptor superfamily

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

New variants of the human and rat nuclear hormone receptor, TR4: expression and chromosomal localization of the human gene

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Induction of the intronic enhancer of the human ciliary neurotrophic factor receptor (CNTFRalpha) gene by the TR4 orphan receptor. A member of steroid receptor superfamily

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Cloning of the gene encoding the murine orphan receptor TAK1 and cell-type-specific expression in testis.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Cloning of rabbit TR4 and its bone cell-specific activity to suppress estrogen receptor-mediated transactivation

1 reference

https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

The DHR78 nuclear receptor is required for ecdysteroid signaling during the onset of Drosophila metamorphosis

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Identification of human TR2 orphan receptor response element in the transcriptional initiation site of the simian virus 40 major late promoter

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Constitutive activation of retinoic acid receptor beta2 promoter by orphan nuclear receptor TR2.

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Suppression of the human erythropoietin gene expression by the TR2 orphan receptor, a member of the steroid receptor superfamily

1 reference

https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Expression of the orphan receptor TR4 during brain development of the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

The genomic structure and chromosomal location of the human TR2 orphan receptor, a member of the steroid receptor superfamily

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Identification of an essential cis-acting element (TR2-PACE) in the 5' promoter of human TR2 orphan receptor gene

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Striking evolutionary conservation of a cis-element related to nuclear receptor target sites and present in TR2 orphan receptor genes.

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

A constitutive nuclear localization signal from the second zinc-finger of orphan nuclear receptor TR2

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Allelic deletions in the long arm of chromosome 12 identify sites of candidate tumor suppressor genes in male germ cell tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Genomic structure, promoter identification, and chromosomal mapping of a mouse nuclear orphan receptor expressed in embryos and adult testes.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Cytogenetic findings indicate heterogeneity in patients with blepharophimosis, epicanthus inversus, and developmental delay

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Overexpression of hexokinase II in transgenic mice. Evidence that increased phosphorylation augments muscle glucose uptake

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

The p53/retinoblastoma-mediated repression of testicular orphan receptor-2 in the rhesus monkey with cryptorchidism

1 reference

https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Negative feedback control of the retinoid-retinoic acid/retinoid X receptor pathway by the human TR4 orphan receptor, a member of the steroid receptor superfamily

1 reference

https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Characterization of an inverted repeat with a zero spacer (IR0)-type retinoic acid response element from the mouse nuclear orphan receptor TR2-11 gene

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Induction of TR4 orphan receptor by retinoic acid in human HaCaT keratinocytes

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Identification of nuclear receptor mRNAs by RT-PCR amplification of conserved zinc-finger motif sequences

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Expression of nuclear hormone receptors in the rat supraoptic nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Suppression of gene expression on the simian virus 40 major late promoter by human TR4 orphan receptor. A member of the steroid receptor superfamily

1 reference

https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

TR4 orphan receptor crosstalks to chicken ovalbumin upstream protein-transcription factor and thyroid hormone receptor to induce the transcriptional activity of the human immunodeficiency virus type 1 long-terminal repeat

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Feedback regulation between orphan nuclear receptor TR2 and human papilloma virus type 16.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

The orphan nuclear receptor TR2 suppresses a DR4 hormone response element of the mouse CRABP-I gene promoter

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Mechanisms of the mouse orphan nuclear receptor TR2-11-mediated gene suppression.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

The orphan receptor TAK1 acts as a repressor of RAR-, RXR- and T3R-mediated signaling pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Thyroid hormone direct repeat 4 response element is a positive regulatory element for the human TR2 orphan receptor, a member of steroid receptor superfamily

1 reference

https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Identification of direct repeat 4 as a positive regulatory element for the human TR4 orphan receptor. A modulator for the thyroid hormone target genes

1 reference

https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Differential regulation of direct repeat 3 vitamin D3 and direct repeat 4 thyroid hormone signaling pathways by the human TR4 orphan receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Regulation of peroxisome proliferator-activated receptor alpha-induced transactivation by the nuclear orphan receptor TAK1/TR4

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Nuclear orphan receptors regulate transcription of the gene for the human luteinizing hormone receptor

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

TR4 orphan receptor represses the human steroid 21-hydroxylase gene expression through the monomeric AGGTCA motif

1 reference

https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Identification of the histamine H1 receptor gene as a differentially repressed target of the human TR2 orphan receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Identification of the human aldolase A gene as the first induced target for the TR2 orphan receptor, a member of the steroid hormone receptor superfamily

1 reference

https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Distal cis-acting elements restrict expression of the CyIIIb actin gene in the aboral ectoderm of the sea urchin embryo.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Characterization of the mouse nuclear orphan receptor TR2-11 gene promoter and its potential role in retinoic acid-induced P19 apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Interaction of steroid hormone receptors with the transcription initiation complex

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Cloning and characterization of mouse RIP140, a corepressor for nuclear orphan receptor TR2.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

A novel nuclear receptor heterodimerization pathway mediated by orphan receptors TR2 and TR4

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Convergence of two repressors through heterodimer formation of androgen receptor and testicular orphan receptor-4: a unique signaling pathway in the steroid receptor superfamily

1 reference

https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Modulation of estrogen receptor-mediated transactivation by orphan receptor TR4 in MCF-7 cells

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Molecular mechanisms of COUP-TF-mediated transcriptional repression: evidence for transrepression and active repression

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Transcriptional repression of eukaryotic promoters

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Orphan nuclear receptors--the first eight years

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

The use of a DNA-binding domain replacement method for the detection of a potential TR3 orphan receptor response element in the mouse mammary tumor virus long terminal repeat

1 reference

https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Identification of natural monomeric response elements of the nuclear receptor RZR/ROR. They also bind COUP-TF homodimers

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

Spermatogenesis and testis development are normal in mice lacking testicular orphan nuclear receptor 2

1 reference

https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900118-8

7 January 2021

10.1016/S0960-0760(02)00118-8

Identifiers

DOI

1 reference

31 July 2017

1 reference

PubMed ID

12361719