Down-regulation of tumor suppressor A kinase anchor protein 12 in human hepatocarcinogenesis by epigenetic mechanisms (Q34146004)

31 July 2017

Down-regulation of tumor suppressor A kinase anchor protein 12 in human hepatocarcinogenesis by epigenetic mechanisms (English)

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31 July 2017

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Arne Warth

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Kai Breuhahn

object named as

Kai Breuhahn

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Michel Mittelbronn

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object named as

Michel Mittelbronn

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31 July 2017

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Arianeb Mehrabi

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Benjamin Goeppert

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Peter Schmezer

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Céline Dutruel

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Christopher Oakes

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Marcus Renner

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Marco Breinig

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Monika Nadja Vogel

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Georg Gdynia

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Roland Penzel

12

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Thomas Longerich

13

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Odilia Popanda

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Christoph Plass

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Peter Schirmacher

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Michael André Kern

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language of work or name

English

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publication date

26 October 2010

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31 July 2017

2023-2033

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Interplay between microRNAs and the epigenetic machinery: an intricate network

31 July 2017

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A-kinase anchoring proteins take shape

21 January 2018

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7 January 2021

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7 January 2021

SSeCKS/Gravin/AKAP12 inhibits cancer cell invasiveness and chemotaxis by suppressing a protein kinase C- Raf/MEK/ERK pathway

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7 January 2021

Disruption of transforming growth factor-beta signaling through beta-spectrin ELF leads to hepatocellular cancer through cyclin D1 activation

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7 January 2021

Neoplastic hepatocyte growth associated with cyclin D1 redistribution from the cytoplasm to the nucleus in mouse hepatocarcinogenesis

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7 January 2021

Loss of the SSeCKS/Gravin/AKAP12 gene results in prostatic hyperplasia

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7 January 2021

SSeCKS metastasis-suppressing activity in MatLyLu prostate cancer cells correlates with vascular endothelial growth factor inhibition

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7 January 2021

AKAP12/Gravin is inactivated by epigenetic mechanism in human gastric carcinoma and shows growth suppressor activity

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7 January 2021

Multiple promoters direct expression of three AKAP12 isoforms with distinct subcellular and tissue distribution profiles

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7 January 2021

Etiology-dependent molecular mechanisms in human hepatocarcinogenesis

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7 January 2021

Protumorigenic overexpression of stathmin/Op18 by gain-of-function mutation in p53 in human hepatocarcinogenesis.

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7 January 2021

Abnormal structure and expression of p53 gene in human hepatocellular carcinoma

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7 January 2021

Cyclin E overexpression responsible for growth of human hepatic tumors with p21WAF1/CIP1/SDI1

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7 January 2021

Isolation and characterization of a human hepatic epithelial-like cell line (AKN-1) from a normal liver

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7 January 2021

miRNA deregulation by epigenetic silencing disrupts suppression of the oncogene PLAG1 in chronic lymphocytic leukemia

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7 January 2021

Functional characterisation of decoy receptor 3 in Crohn's disease

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7 January 2021

In vitro radiation-induced expression of XPC mRNA as a possible biomarker for developing adverse reactions during radiotherapy

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7 January 2021

Profiling microRNA expression in hepatocellular carcinoma reveals microRNA-224 up-regulation and apoptosis inhibitor-5 as a microRNA-224-specific target.

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7 January 2021

Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets

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7 January 2021

AKAP12, a gene with tumour suppressor properties, is a target of promoter DNA methylation in childhood myeloid malignancies.

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7 January 2021

SSeCKS, a major protein kinase C substrate with tumor suppressor activity, regulates G(1)-->S progression by controlling the expression and cellular compartmentalization of cyclin D.

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7 January 2021

Mechanistic and prognostic significance of aberrant methylation in the molecular pathogenesis of human hepatocellular carcinoma

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7 January 2021

Promoter methylation of genes in and around the candidate lung cancer susceptibility locus 6q23-25.

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7 January 2021

Actin filament formation, reorganization and migration are impaired in hepatic stellate cells under influence of trichostatin A, a histone deacetylase inhibitor

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7 January 2021

v-Src-mediated down-regulation of SSeCKS metastasis suppressor gene promoter by the recruitment of HDAC1 into a USF1-Sp1-Sp3 complex

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7 January 2021

Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals

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7 January 2021

Identifiers

DOI

10.1002/HEP.23939

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31 July 2017

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