Discovery of a novel and potent class of FabI-directed antibacterial agents (Q34143489)

31 July 2017

Discovery of a novel and potent class of FabI-directed antibacterial agents (English)

1 reference

31 July 2017

David J Payne

1

1 reference

31 July 2017

William H Miller

2

1 reference

31 July 2017

Valerie Berry

3

1 reference

31 July 2017

John Brosky

4

1 reference

31 July 2017

Walter J Burgess

5

1 reference

31 July 2017

Emile Chen

6

1 reference

31 July 2017

Walter E DeWolf Jr

7

1 reference

31 July 2017

Andrew P Fosberry

8

1 reference

31 July 2017

Rebecca Greenwood

9

1 reference

31 July 2017

Martha S Head

10

1 reference

31 July 2017

Dirk A Heerding

11

1 reference

31 July 2017

Cheryl A Janson

12

1 reference

31 July 2017

Deborah D Jaworski

13

1 reference

31 July 2017

Paul M Keller

14

1 reference

31 July 2017

Peter J Manley

15

1 reference

31 July 2017

Terrance D Moore

16

1 reference

31 July 2017

Kenneth A Newlander

17

1 reference

31 July 2017

Stewart Pearson

18

1 reference

31 July 2017

Brian J Polizzi

19

1 reference

31 July 2017

Xiayang Qiu

20

1 reference

31 July 2017

Stephen F Rittenhouse

21

1 reference

31 July 2017

Courtney Slater-Radosti

22

1 reference

31 July 2017

Kevin L Salyers

23

1 reference

31 July 2017

Mark A Seefeld

24

1 reference

31 July 2017

Martin G Smyth

25

1 reference

31 July 2017

Dennis T Takata

26

1 reference

31 July 2017

Irene N Uzinskas

27

1 reference

31 July 2017

Kalindi Vaidya

28

1 reference

31 July 2017

Nicola G Wallis

29

1 reference

31 July 2017

Scott B Winram

30

1 reference

31 July 2017

Catherine C K Yuan

31

1 reference

31 July 2017

William F Huffman

32

1 reference

31 July 2017

language of work or name

English

0 references

publication date

1 October 2002

1 reference

Antimicrobial Agents and Chemotherapy

31 July 2017

1 reference

31 July 2017

46

1 reference

31 July 2017

3118-3124

1 reference

31 July 2017

10

1 reference

Discovery of aminopyridine-based inhibitors of bacterial enoyl-ACP reductase (FabI)

31 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128775

Bacterial fatty-acid biosynthesis: a genomics-driven target for antibacterial drug discovery

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128775

The millennium bugs--the need for and development of new antibacterials

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128775

Identification and characterization of inhibitors of multidrug resistance efflux pumps in Pseudomonas aeruginosa: novel agents for combination therapy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128775

Characterization of Pseudomonas aeruginosa enoyl-acyl carrier protein reductase (FabI): a target for the antimicrobial triclosan and its role in acylated homoserine lactone synthesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128775

Efficacy of high-dose amoxicillin-clavulanate against experimental respiratory tract infections caused by strains of Streptococcus pneumoniae

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128775

Broad spectrum antimicrobial biocides target the FabI component of fatty acid synthesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128775

Triclosan targets lipid synthesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128775

The acrAB homolog of Haemophilus influenzae codes for a functional multidrug efflux pump

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128775

A mechanism of drug action revealed by structural studies of enoyl reductase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128775

Biochemical and genetic characterization of the action of triclosan on Staphylococcus aureus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128775

The enoyl-[acyl-carrier-protein] reductase (FabI) of Escherichia coli, which catalyzes a key regulatory step in fatty acid biosynthesis, accepts NADH and NADPH as cofactors and is inhibited by palmitoyl-CoA.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128775

Erratum: A triclosan-resistant bacterial enzyme

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12234833

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Enoyl-acyl carrier protein reductase (fabI) plays a determinant role in completing cycles of fatty acid elongation in Escherichia coli

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12234833

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/AAC.46.10.3118-3124.2002

1 reference

31 July 2017

1 reference

31 July 2017

1 reference