Recessive oncogenes: current status (Q34138129)

31 July 2017

Recessive oncogenes: current status (English)

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31 July 2017

Xiang Gao

1

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PubMed ID

11173562

31 July 2017

Kenneth V Honn

series ordinal

2

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31 July 2017

1 January 1995

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Pathology Oncology Research

31 July 2017

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31 July 2017

1

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31 July 2017

1

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31 July 2017

7-22

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https://scigraph.springernature.com/pub.10.1007/bf02893578

31 July 2017

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cites work

Cell cycle analysis of p53-induced cell death in murine erythroleukemia cells

1 reference

https://api.crossref.org/works/10.1007%2FBF02893578

The p53 activation domain binds the TATA box-binding polypeptide in Holo-TFIID, and a neighboring p53 domain inhibits transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02893578

State of adenomatous polyposis coli gene and ras oncogenes in Japanese prostate cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02893578

Analysis of mutations at the neurofibromatosis 1 (NF1) locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02893578

Common origins of BRCA1 mutations in Canadian breast and ovarian cancer families

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02893578

Mutation and cancer: statistical study of retinoblastoma

21 January 2018

1 reference

12 December 2020

Three discrete regions of deletion at 3p in head and neck cancers

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12 December 2020

Localization of the 9p Melanoma Susceptibility Locus (MLM) to a 2-cM Region between D9S736 and D9S171

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12 December 2020

The hunt for Ras targets

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12 December 2020

p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21

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12 December 2020

Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis

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12 December 2020

p53 binds to the TATA-binding protein-TATA complex.

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12 December 2020

A Large Kindred With 17q-Linked Breast and Ovarian Cancer: Genetic, Phenotypic, and Genealogical Analysis

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12 December 2020

Wild-type p53 is a cell cycle checkpoint determinant following irradiation

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12 December 2020

A region of homozygous deletion on chromosome 9p21-22 in primary nasopharyngeal carcinoma

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12 December 2020

p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest

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12 December 2020

Homozygous inactivation of WT1 in a Wilms' tumor associated with the WAGR syndrome.

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12 December 2020

Familial male breast cancer is not linked to the BRCA1 locus on chromosome 17q.

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12 December 2020

Identification of a chromosome 18q gene that is altered in colorectal cancers

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12 December 2020

Frequent somatic mutation of the MTS1/CDK4I (multiple tumor suppressor/cyclin-dependent kinase 4 inhibitor) gene in esophageal squamous cell carcinoma.

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12 December 2020

Association of the APC tumor suppressor protein with catenins

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12 December 2020

WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis

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12 December 2020

Fine structure analysis of the WT1 gene in sporadic Wilms tumors

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12 December 2020

Dimer formation by an N-terminal coiled coil in the APC protein

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12 December 2020

Homozygous deletion mapping at 9p21 in bladder carcinoma defines a critical region within 2cM of IFNA

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12 December 2020

CDKN2 (p16/MTS1) gene deletion or CDK4 amplification occurs in the majority of glioblastomas.

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12 December 2020

Homozygous deletions of the multiple tumor suppressor gene 1 in the progression of human astrocytomas.

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12 December 2020

Loss of heterozygosity in cervical carcinoma: subchromosomal localization of a putative tumor-suppressor gene to chromosome 11q22-q24

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12 December 2020

Localization of tumor suppressor loci on chromosome 9 in primary human renal cell carcinomas

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12 December 2020

A tumor suppressor locus within 3p14-p12 mediates rapid cell death of renal cell carcinoma in vivo

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12 December 2020

Transcriptional repression of the insulin-like growth factor I receptor (IGF-I-R) gene by the tumor suppressor WT1 involves binding to sequences both upstream and downstream of the IGF-I-R gene transcription start site

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12 December 2020

NIH3T3 cells expressing the deleted in colorectal cancer tumor suppressor gene product stimulate neurite outgrowth in rat PC12 pheochromocytoma cells

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12 December 2020

Loss of chromosome arm 8p loci in prostate cancer: Mapping by quantitative allelic imbalance

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12 December 2020

Tumor suppressor genes

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12 December 2020

Mitotic recombination of chromosome 17 in astrocytomas

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12 December 2020

p53 Mutation and MDM2 amplification in human soft tissue sarcomas

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12 December 2020

Correlation of loss of heterozygosity at 11 p with tumour progression and survival in non‐small cell lung cancer

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12 December 2020

Differential suppression of mammary and prostate cancer metastasis by human chromosomes 17 and 11

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12 December 2020

Suppression of tumorigenicity of human prostate carcinoma cells by replacing a mutated RB gene.

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12 December 2020

Distinct deletions of chromosome 9p associated with melanoma versus glioma, lung cancer, and leukemia.

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12 December 2020

Absence of p16INK4 protein is restricted to the subset of lung cancer lines that retains wildtype RB

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12 December 2020

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12 December 2020

Cell cycle regulation of the human cdc2 gene

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12 December 2020

The APC gene product in normal and tumor cells

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12 December 2020

Somatic allelic loss at the DCC, APC, nm23-H1 and p53 tumor suppressor gene loci in human prostatic carcinoma.

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12 December 2020

Identification and characterization of the familial adenomatous polyposis coli gene

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12 December 2020

Direct interaction between the transcriptional activation domain of human p53 and the TATA box-binding protein

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12 December 2020

Repression of the transforming growth factor-beta 1 gene by the Wilms' tumor suppressor WT1 gene product

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12 December 2020

Allelotyping of human prostatic adenocarcinoma

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12 December 2020

p53-dependent G1 arrest involves pRB-related proteins and is disrupted by the human papillomavirus 16 E7 oncoprotein

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12 December 2020

p53 mutations in benign prostatic hyperplasia.

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12 December 2020

The DCC gene: structural analysis and mutations in colorectal carcinomas

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12 December 2020

Transcriptional regulation. A closer look at E2F.

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12 December 2020

WAF1, a potential mediator of p53 tumor suppression

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12 December 2020

Transcriptional repression mediated by the WT1 Wilms tumor gene product

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12 December 2020

Loss of heterozygosity on the short arm of chromosome 3 in mesothelioma cell lines and solid tumors

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12 December 2020

Loss of heterozygosity in familial tumors from three BRCA1-linked kindreds

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12 December 2020

State of p53, Rb and DCC tumor suppressor genes in human oral cancer cell lines

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12 December 2020

Analysis of the 11p13 Wilms' tumor suppressor gene (WT1) in ovarian tumors

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12 December 2020

p53 abnormalities and genomic instability in primary human breast carcinomas

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12 December 2020

p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest

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12 December 2020

Domains of the adenovirus E1A protein required for oncogenic activity are also required for dissociation of E2F transcription factor complexes

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12 December 2020

Growth suppression by p18, a p16INK4/MTS1- and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function

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12 December 2020

WT1 mutations in patients with Denys-Drash syndrome: a novel mutation in exon 8 and paternal allele origin

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12 December 2020

Homozygous deletion and frequent allelic loss of chromosome 8p22 loci in human prostate cancer

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12 December 2020

Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms

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12 December 2020

Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers

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12 December 2020

p16 alterations and deletion mapping of 9p21-p22 in malignant mesothelioma

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12 December 2020

Tumor-suppressor p53 and the cell cycle

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12 December 2020

Cooperation between oncogenes

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12 December 2020

p53 mutations in human cancers

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12 December 2020

Loss of the normal NF1 allele from the bone marrow of children with type 1 neurofibromatosis and malignant myeloid disorders

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12 December 2020

Molecular themes in oncogenesis

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12 December 2020

Allelic loss at chromosomes 3p, 8p, 13q, and 17p associated with poor prognosis in head and neck cancer

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12 December 2020

Deletion mapping of chromosomes 8, 10, and 16 in human prostatic carcinoma.

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12 December 2020

p53 gene mutations in Chinese human testicular seminoma

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12 December 2020

Analysis of the p16 gene (CDKN2) as a candidate for the chromosome 9p melanoma susceptibility locus

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12 December 2020

Interleukin-2-mediated elimination of the p27Kip1 cyclin-dependent kinase inhibitor prevented by rapamycin

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12 December 2020

Cloning and characterization of a mouse gene with homology to the human von Hippel-Lindau disease tumor suppressor gene: implications for the potential organization of the human von Hippel-Lindau disease gene

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12 December 2020

Alteration in a new gene encoding a putative membrane-organizing protein causes neuro-fibromatosis type 2

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12 December 2020

Base transitions are the most frequent genetic changes at P53 in gastric cancer

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12 December 2020

Mutations of the VHL tumour suppressor gene in renal carcinoma

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12 December 2020

Loss of heterozygosity in human primary prostate carcinomas: a possible tumor suppressor gene at 7q31.1

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12 December 2020

The Wilms' tumor gene product WT1 activates or suppresses transcription through separate functional domains

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12 December 2020

The p53-mdm-2 autoregulatory feedback loop

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12 December 2020

Sequence-specific DNA binding by p53: identification of target sites and lack of binding to p53 - MDM2 complexes

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12 December 2020

Mediation of c-Myc-induced apoptosis by p53.

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12 December 2020

Specific repression of TATA-mediated but not initiator-mediated transcription by wild-type p53.

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12 December 2020

A P1-based physical map of the region from D17S776 to D17S78 containing the breast cancer susceptibility gene BRCA1

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12 December 2020

The DCC gene product in cellular differentiation and colorectal tumorigenesis

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12 December 2020

Incidence of cancer in 161 families affected by ataxia-telangiectasia

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12 December 2020

The APC gene product associates with microtubules in vivo and promotes their assembly in vitro.

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12 December 2020

Infrequent inactivation of the retinoblastoma gene despite frequent loss of chromosome 13q in head and neck squamous cell carcinoma

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12 December 2020

Loss of heterozygosity of the BRCA1 and other loci on chromosome 17q in human prostate cancer

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12 December 2020

Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus

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12 December 2020

Rates of p16 (MTS1) mutations in primary tumors with 9p loss

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12 December 2020

Definition of a consensus binding site for p53

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12 December 2020

Has the breast cancer gene been found?

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12 December 2020

Localization of a putative tumor suppressor gene by using homozygous deletions in melanomas

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12 December 2020

Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma

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12 December 2020

P16 gene in uncultured tumours

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12 December 2020

Confirmation of BRCA1 by analysis of germline mutations linked to breast and ovarian cancer in ten families

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12 December 2020

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12 December 2020

p53 in prostate cancer: frequent expressed transition mutations

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12 December 2020

Linkage analysis of chromosome 17q markers and breast-ovarian cancer in Icelandic families, and possible relationship to prostatic cancer.

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12 December 2020

Detailed mapping of germline deletions of the von Hippel-Lindau disease tumour suppressor gene.

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12 December 2020

Identification of a Gene Located at Chromosome 5q21 that Is Mutated in Colorectal Cancers

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12 December 2020

p21 is a universal inhibitor of cyclin kinases

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12 December 2020

Cloning of novel Wilms tumor gene (WT1) cDNAs; evidence for antisense transcription of WT1.

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12 December 2020

Identification of intragenic mutations in the von Hippel-Lindau disease tumour suppressor gene and correlation with disease phenotype

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12 December 2020

The catalytic domain of the neurofibromatosis type 1 gene product stimulates ras GTPase and complements ira mutants of S. cerevisiae

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12 December 2020

Tumor progression and loss of heterozygosity at 5q and 18q in non-small cell lung cancer

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12 December 2020

Allele loss on chromosome 16q24.2-qter occurs frequently in breast cancers irrespectively of differences in phenotype and extent of spread

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12 December 2020

Deletion mapping of chromosome 8p in prostate cancer by fluorescence in situ hybridization

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12 December 2020

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

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12 December 2020

WT1: a novel tumor suppressor gene inactivated in Wilms' tumor

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12 December 2020

Allelic loss of chromosomes 16q and 10q in human prostate cancer

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12 December 2020

The gene for hereditary breast-ovarian cancer, BRCA1, maps distal to EDH17B2 in chromosome region 17q12-q21

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12 December 2020

Analysis of the p53 gene and its expression in human glioblastoma cells

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12 December 2020

A novel moesin-, ezrin-, radixin-like gene is a candidate for the neurofibromatosis 2 tumor suppressor.

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12 December 2020

A tumor suppressor gene on chromosome 1p32-pter controls the amplification of MYC family genes in breast cancer

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12 December 2020

Promoter deletion and loss of retinoblastoma gene expression in human prostate carcinoma

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12 December 2020

Germline p16 mutations in familial melanoma

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12 December 2020

In vivo occurrence of p16 (MTS1) and p15 (MTS2) alterations preferentially in non-small cell lung cancers

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12 December 2020

Wild-type p53 suppresses growth of human prostate cancer cells containing mutant p53 alleles

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12 December 2020

Fine deletion mapping on the long arm of chromosome 9 in sporadic and familial basal cell carcinomas

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12 December 2020

Identical allelic loss on chromosome 11q13 in microdissected in situ and invasive human breast cancer

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12 December 2020

When the products of oncogenes and anti-oncogenes meet

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12 December 2020

p53 and K-RAS alterations in pancreatic epithelial cell lesions

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12 December 2020

p53 function and dysfunction

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12 December 2020

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12 December 2020

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

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12 December 2020

Loss of heterozygosity of the retinoblastoma and adenomatous polyposis susceptibility gene loci and in chromosomes 10p, 10q and 16q in human prostate cancer

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12 December 2020

Evidence for involvement of BRCA1 in sporadic breast carcinomas

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12 December 2020

Loss of heterozygosity of chromosome 8 microsatellite loci implicates a candidate tumor suppressor gene between the loci D8S87 and D8S133 in human prostate cancer

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12 December 2020

The MTS1 gene is frequently mutated in primary human esophageal tumors

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12 December 2020

High frequency of nonsense mutations in the NF2 gene caused by C to T transitions in five CGA codons

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12 December 2020

Wild-type p53 activates transcription in vitro

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12 December 2020

Molecular abnormalities of mdm2 and p53 genes in adult soft tissue sarcomas

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12 December 2020

Point mutations and allelic deletion of tumor suppressor gene DCC in human esophageal squamous cell carcinomas and their relation to metastasis

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12 December 2020

The tumor suppressor genes

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12 December 2020

p53-independent expression of p21Cip1 in muscle and other terminally differentiating cells

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12 December 2020

p53: at the crossroads of molecular carcinogenesis and risk assessment

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12 December 2020

Antisense RNA to the putative tumor-suppressor gene DCC transforms Rat-1 fibroblasts

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12 December 2020

Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

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12 December 2020

Reciprocal Rb inactivation and p16INK4 expression in primary lung cancers and cell lines.

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12 December 2020

Two molecular pathways to transitional cell carcinoma of the bladder.

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12 December 2020

Evidence for a tumor suppressor gene on chromosome 19q associated with human astrocytomas, oligodendrogliomas, and mixed gliomas

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12 December 2020

Allelotype of human bladder cancer

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12 December 2020

Wild-type but not mutant p53 can repress transcription initiation in vitro by interfering with the binding of basal transcription factors to the TATA motif

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12 December 2020

KAI1, a metastasis suppressor gene for prostate cancer on human chromosome 11p11.2

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12 December 2020

Loss of heterozygosity studies in tumors from families with breast-ovarian cancer syndrome

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12 December 2020

DNA damage induced p53 mediated transcription is inhibited by human papillomavirus type 18 E6

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12 December 2020

High-frequency of loss of expression and allelic deletion of the apc and mcc genes in human prostate-cancer

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12 December 2020

Analysis of retinoblastoma (RB) gene deletion in human prostatic carcinomas

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12 December 2020

Frequent loss of heterozygosity on chromosome 9 in adenocarcinoma and squamous cell carcinoma of the esophagus.

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12 December 2020

Binding of the Wilms' tumor locus zinc finger protein to the EGR-1 consensus sequence

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12 December 2020

Loss of heterozygosity in sporadic human breast carcinoma: a common region between 11q22 and 11q23.3.

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12 December 2020

A major segment of the neurofibromatosis type 1 gene: cDNA sequence, genomic structure, and point mutations

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12 December 2020

Expression of transcription factor E2F1 induces quiescent cells to enter S phase

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12 December 2020

Frequent allelic deletions and loss of expression characterize the DCC gene in male germ cell tumors

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12 December 2020

Loss of heterozygosity on chromosome 11p13 in primary bladder carcinoma

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12 December 2020

Frequent loss of expression and loss of heterozygosity of the putative tumor suppressor gene DCC in prostatic carcinomas

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12 December 2020

Linkage of early-onset familial breast cancer to chromosome 17q21

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12 December 2020

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

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12 December 2020

Identification of FAP locus genes from chromosome 5q21

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12 December 2020

Aflatoxin B1 induces the transversion of G-->T in codon 249 of the p53 tumor suppressor gene in human hepatocytes

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12 December 2020

Association between wild type and mutant APC gene products.

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12 December 2020

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

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12 December 2020

Growth arrest by induction of p53 in DNA damaged keratinocytes is bypassed by human papillomavirus 16 E7.

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12 December 2020

Frequent somatic mutations and loss of heterozygosity of the von Hippel-Lindau tumor suppressor gene in primary human renal cell carcinomas.

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12 December 2020

Mutations in the BRCA1 gene in families with early-onset breast and ovarian cancer

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12 December 2020

DCC gene alteration in human endometrial carcinomas

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12 December 2020

Molecular analysis of the von Hippel-Lindau disease tumor suppressor gene in human lung cancer cell lines.

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12 December 2020

Molecular characterization of the retinoblastoma susceptibility gene

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12 December 2020

Frequent loss of chromosome 9 in human primary non-small cell lung cancer

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12 December 2020

The role of WT1 in Wilms tumorigenesis

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12 December 2020

Modulation of DNA binding specificity by alternative splicing of the Wilms tumor wt1 gene transcript

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12 December 2020

Differential induction of transcriptionally active p53 following UV or ionizing radiation: defects in chromosome instability syndromes?

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12 December 2020

Involvement of CDKN2 (p16INK4A/MTS1) and p15INK4B/MTS2 in human leukemias and lymphomas.

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12 December 2020

Loss of heterozygosity involving the APC gene in oral squamous cell carcinomas.

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12 December 2020

Wild-type but not mutant APC associates with the microtubule cytoskeleton.

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12 December 2020

A cell cycle-regulated inhibitor of cyclin-dependent kinases

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12 December 2020

Mutation rate of the CDKN2 gene in malignant gliomas.

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12 December 2020

Correlation of terminal cell cycle arrest of skeletal muscle with induction of p21 by MyoD.

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12 December 2020

Mutations in the p53 gene at codon 249 are rare in squamous-cell carcinoma of the head and neck.

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12 December 2020

The tumor suppressor protein p53 strongly alters human immunodeficiency virus type 1 replication

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12 December 2020

Type 1 neurofibromatosis gene: identification of a large transcript disrupted in three NF1 patients

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12 December 2020

Joining the complex: cyclin-dependent kinase inhibitory proteins and the cell cycle

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12 December 2020

Expression of the DCC gene in myelodysplastic syndromes and overt leukemia

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12 December 2020

Tumor suppressor genes

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12 December 2020

Expression and alternative splicing of the deleted in colorectal cancer (DCC) gene in normal and malignant tissues

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12 December 2020

The Wilms tumour gene WT1 is expressed in murine mesoderm-derived tissues and mutated in a human mesothelioma

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12 December 2020

Retinoblastoma protein switches the E2F site from positive to negative element

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12 December 2020

Deletion of p16 and p15 genes in brain tumors

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12 December 2020

A cell cycle regulator potentially involved in genesis of many tumor types

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12 December 2020

Mutations of the p53 gene in carcinomas of the urinary system.

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12 December 2020

Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma

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12 December 2020

Somatic mutations of the von Hippel-Lindau tumor suppressor gene in sporadic central nervous system hemangioblastomas.

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12 December 2020

p53-independent induction of WAF1/CIP1 in human leukemia cells is correlated with growth arrest accompanying monocyte/macrophage differentiation.

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12 December 2020

Identifiers

DOI

10.1007/BF02893578

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31 July 2017

1 reference

PubMed ID

11173562